{"hash":"1618491739859199190","title":"Neuronal proteostasis and stress response","description":"GO terms center on translation, protein quality control (unfolded protein response, aggresome assembly, ubiquitination with K48 and K11 linkages), and neuron-specific maintenance (neuron maturation, neuron cellular homeostasis, oxidative stress regulation). Together these suggest a neuronal proteostasis network that preserves protein balance and cell viability under stress, including energy and redox considerations. Thus, a concise label is neuronal proteostasis and stress response.","confidence":"Medium","size":6,"edges":3,"triangles":1,"max_degree":2,"top_function":null,"members":[{"accession":"XP_065991964.1","go_terms":["GO:0035774","GO:0000423","GO:0032436","GO:0000266","GO:0099074","GO:0090201","GO:0033132","GO:0051865","GO:0043388","GO:0051583","GO:0036205","GO:0051412","GO:0023035","GO:0046329","GO:1903265","GO:0070936","GO:0090258","GO:0006986","GO:0070842","GO:0070979","GO:0048078","GO:0090141","GO:0010918","GO:0085020","GO:0042787","GO:1902283","GO:0071287","GO:1903427","GO:0070534","GO:0043123","GO:0060546","GO:0010636","GO:1903382","GO:2001171","GO:1902530","GO:0055069","GO:1905366","GO:0008344","GO:1903542","GO:0097039","GO:0010637","GO:0090394","GO:1904049","GO:0097237","GO:0042551","GO:0070050","GO:0006513","GO:1903378","GO:0051967","GO:0006351","GO:1903377","GO:0046676"]},{"accession":"XP_065988143.1","go_terms":["GO:0006450","GO:0006431","GO:0006438","GO:0006428","GO:0006429","GO:0006412"]},{"accession":"XP_065994987.1","go_terms":[]},{"accession":"XP_065997398.1","go_terms":["GO:0000447"]},{"accession":"XP_025183403.2","go_terms":["GO:0042273","GO:0032092","GO:2000059","GO:0006605","GO:0050821","GO:1904667","GO:2000435","GO:0006412","GO:0000027"]},{"accession":"XP_025180413.1","go_terms":["GO:0099132","GO:0042777"]}],"graph":[["XP_025183403.2","XP_025180413.1",0.98],["XP_025183403.2","XP_065988143.1",0.669],["XP_025180413.1","XP_065988143.1",0.587]],"all_go_terms":{"GO:0006986":1,"GO:0070936":1,"GO:0042551":1,"GO:0070842":1,"GO:0070050":1,"GO:2001171":1,"GO:0070979":1,"GO:1903427":1,"GO:1903377":1,"GO:0055069":1,"GO:0010918":1,"GO:0051865":1,"GO:0090201":1,"GO:0036205":1,"GO:0090258":1,"GO:0090394":1,"GO:0097237":1,"GO:0035774":1,"GO:0085020":1,"GO:1904049":1,"GO:0051583":1,"GO:0010636":1,"GO:0051412":1,"GO:0043388":1,"GO:0090141":1,"GO:0060546":1,"GO:1902530":1,"GO:1903382":1,"GO:1902283":1,"GO:0008344":1,"GO:0097039":1,"GO:0046676":1,"GO:0032436":1,"GO:0006351":1,"GO:0010637":1,"GO:0000423":1,"GO:0051967":1,"GO:1905366":1,"GO:0000266":1,"GO:1903542":1,"GO:0006513":1,"GO:0070534":1,"GO:1903378":1,"GO:1903265":1,"GO:0043123":1,"GO:0099074":1,"GO:0048078":1,"GO:0023035":1,"GO:0033132":1,"GO:0046329":1,"GO:0071287":1,"GO:0042787":1,"GO:0006429":1,"GO:0006431":1,"GO:0006428":1,"GO:0006412":2,"GO:0006450":1,"GO:0006438":1,"GO:0000447":1,"GO:2000059":1,"GO:0050821":1,"GO:0006605":1,"GO:2000435":1,"GO:0042273":1,"GO:1904667":1,"GO:0000027":1,"GO:0032092":1,"GO:0042777":1,"GO:0099132":1},"recipe_readded":["XP_065993013.1","XP_066003460.1","XP_065998850.1","XP_025166482.1","XP_025167842.1","XP_025182222.2","XP_025187542.2","XP_025167115.1","XP_066000094.1","XP_025188152.1","XP_065992409.1","XP_025177951.2","XP_025182356.1","XP_065995638.1","XP_065997304.1","XP_025188647.2","XP_025173037.2","XP_025166792.2","XP_066000093.1","XP_025164874.2"]}