{"hash":"2040167601568851884","title":"Ubiquitin-Proteasome\u2013NF-\u03baB Immune Signaling","description":"The cluster combines deubiquitination, non-canonical NF-\u03baB and TNF signaling, MHC I antigen processing, and proteasome assembly, pointing to immune signaling tightly linked to protein degradation. While some terms (Wnt, cell cycle regulation) may reflect cross-talk via ubiquitination and stress responses, the core terms converge on ubiquitin-proteasome\u2013driven immune pathways. This supports a cohesive immune/degradation function cluster with high confidence.","confidence":"High","size":22,"edges":205,"triangles":1124,"max_degree":21,"top_function":null,"members":[{"accession":"XP_051451554.1","go_terms":["GO:0034389","GO:0007253","GO:0031134","GO:1904293","GO:0031468","GO:0002814","GO:2000157","GO:0030433","GO:0061060","GO:0008219","GO:1903094"]},{"accession":"XP_051451633.1","go_terms":["GO:0090263","GO:0038061","GO:0033209","GO:0010043","GO:0009651","GO:0051437","GO:0051436","GO:0061418","GO:0080129","GO:0043488","GO:0006521","GO:0002479","GO:0046686","GO:0002223","GO:0090090","GO:0050852","GO:0031146","GO:0031145","GO:0060071","GO:0010972","GO:0010950","GO:0002862","GO:0038095","GO:0010363","GO:0016579","GO:0010499","GO:0016032"]},{"accession":"XP_051452248.1","go_terms":["GO:0090263","GO:0038061","GO:0033209","GO:0051437","GO:0051436","GO:0061418","GO:0080129","GO:0006521","GO:0002223","GO:0090090","GO:0050852","GO:0031146","GO:0031145","GO:0002862","GO:0010972","GO:0060071","GO:0010499","GO:0016032","GO:0010043","GO:0009651","GO:0043488","GO:0002479","GO:0046686","GO:0010950","GO:0038095","GO:0010363","GO:0016579"]},{"accession":"XP_051454793.1","go_terms":["GO:0090263","GO:0038061","GO:0033209","GO:0051437","GO:0051436","GO:0061418","GO:0080129","GO:0006521","GO:0002223","GO:0090090","GO:0050852","GO:0031146","GO:0031145","GO:0002862","GO:0010972","GO:0060071","GO:0010499","GO:0016032","GO:0010043","GO:0009651","GO:0043488","GO:0002479","GO:0046686","GO:0010950","GO:0038095","GO:0010363","GO:0016579"]},{"accession":"XP_051458715.1","go_terms":["GO:0045190","GO:0009688","GO:0044810","GO:0090282","GO:0090419","GO:0009190","GO:0033624","GO:0021693","GO:1903468","GO:0034244","GO:1990705","GO:0032487","GO:0051237","GO:0070535","GO:0035196","GO:0072383","GO:0007249","GO:0090055","GO:0021685","GO:1905150"]},{"accession":"XP_051463340.1","go_terms":["GO:0035103","GO:1900039","GO:0000423","GO:1901097","GO:0033132","GO:1902236","GO:1901340","GO:1903265","GO:0021888","GO:0014070","GO:0010216","GO:0045648","GO:0002109","GO:0006357","GO:0035973","GO:1901799","GO:1902283","GO:0016579","GO:1904378","GO:0030474","GO:0017085","GO:1903071","GO:0006289","GO:0051865","GO:0034140","GO:0030433","GO:0016925","GO:1905366","GO:0000028","GO:0010636","GO:0010637","GO:0000753","GO:0071816","GO:0070842","GO:0097237","GO:1900186","GO:1904021","GO:0006517","GO:1904049","GO:0006412"]},{"accession":"XP_051463788.1","go_terms":["GO:0090263","GO:0038061","GO:0033209","GO:0051437","GO:0051436","GO:0061418","GO:0080129","GO:0006521","GO:0002223","GO:0090090","GO:0050852","GO:0031146","GO:0031145","GO:0002862","GO:0010972","GO:0060071","GO:0010499","GO:0016032","GO:0010043","GO:0009651","GO:0043488","GO:0002479","GO:0046686","GO:0010950","GO:0038095","GO:0010363","GO:0016579"]},{"accession":"XP_051454798.1","go_terms":["GO:0034727","GO:0000422","GO:0061723","GO:0006501","GO:0035096","GO:0044805","GO:0032258","GO:0000045","GO:0000226","GO:0034198","GO:0010940","GO:0010040","GO:0034629","GO:0040024","GO:0008625","GO:0006888","GO:0097352","GO:0071211","GO:0070301","GO:0010288","GO:0061709","GO:0006915","GO:0043278","GO:0071280","GO:0070257"]},{"accession":"XP_051453236.1","go_terms":["GO:0099641","GO:0071480","GO:0032387","GO:0050821","GO:0032355","GO:0009644","GO:0030308","GO:0032463","GO:2000378","GO:0070309","GO:0006936","GO:0070141","GO:0031109","GO:0009408","GO:0007568","GO:0042542","GO:1900034","GO:0051403","GO:1905907"]},{"accession":"XP_051454804.1","go_terms":["GO:0006284","GO:0097510"]},{"accession":"XP_051459613.1","go_terms":["GO:0045190","GO:0009688","GO:0044810","GO:0090282","GO:0090419","GO:0009190","GO:0033624","GO:0021693","GO:1903468","GO:0034244","GO:1990705","GO:0032487","GO:0051237","GO:0070535","GO:0035196","GO:0072383","GO:0007249","GO:0090055","GO:0021685","GO:1905150"]},{"accession":"XP_051456706.1","go_terms":["GO:0016330","GO:0031115","GO:1990108","GO:0010803","GO:0050862","GO:0018230","GO:0007023","GO:0000743","GO:0051081","GO:0043369","GO:0044091","GO:0034454","GO:0014889","GO:0031122","GO:0048491","GO:0044861","GO:0072321","GO:0042347","GO:0072383","GO:1901026","GO:0010457","GO:0048936","GO:0090063","GO:0045577","GO:0031117","GO:0034126"]},{"accession":"XP_051452108.1","go_terms":["GO:0032436","GO:0070911","GO:0034126","GO:0090204","GO:0010286","GO:1901896","GO:0071276","GO:0043392","GO:0060334","GO:0051572","GO:0016925","GO:0043433","GO:0035186","GO:0086004","GO:0030578","GO:1902260","GO:0045944","GO:0045759","GO:0000423","GO:1901097","GO:0033132","GO:1902236","GO:1901340","GO:1903265","GO:0021888","GO:0014070","GO:0010216","GO:0045648","GO:0002109","GO:0006357","GO:0035973","GO:1901799","GO:1902283","GO:0016579","GO:1904378","GO:0030474","GO:0017085","GO:1903071","GO:0006289","GO:0051865","GO:0034140","GO:0030433","GO:1905366","GO:0000028","GO:0010636","GO:0010637","GO:0000753","GO:0071816","GO:0070842","GO:0097237","GO:1900186","GO:1904021","GO:0006517","GO:1904049","GO:0006412"]},{"accession":"XP_051454235.1","go_terms":["GO:0006777","GO:0016236","GO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