{"hash":"730149825129004821","title":"Ribosome Biogenesis and SRP-Dependent Translation","description":"This cluster is anchored by ribosome-related terms: maturation of SSU-rRNA and SRP-dependent cotranslational targeting to the membrane, pointing to roles in ribosome assembly and nascent polypeptide targeting to the ER. Additional entries linking proliferation, apoptosis, and DNA damage response suggest a ribosomal-stress\u2013driven network that connects ribosome function to cell-cycle control and genome integrity. A few outliers (like seminiferous tubule development) exist, but the core theme remains translation/ ribosome biology.","confidence":"Medium","size":17,"edges":9,"triangles":0,"max_degree":5,"top_function":null,"members":[{"accession":"XP_051389271.1","go_terms":[]},{"accession":"XP_051389619.1","go_terms":[]},{"accession":"XP_051390103.1","go_terms":[]},{"accession":"XP_051390862.1","go_terms":[]},{"accession":"XP_051391276.1","go_terms":["GO:0006614","GO:0006616"]},{"accession":"XP_051391502.1","go_terms":["GO:2000873","GO:0072520","GO:0007141","GO:0043065","GO:0030511","GO:0016479","GO:0008285","GO:0061408","GO:0043966","GO:0043968","GO:2000219","GO:0031065","GO:0048133","GO:0006978","GO:1900404","GO:0043982","GO:0043983","GO:0043981","GO:0061188","GO:0061186","GO:2000772"]},{"accession":"XP_051391619.1","go_terms":[]},{"accession":"XP_051393063.1","go_terms":[]},{"accession":"XP_051393954.1","go_terms":["GO:0009553","GO:0042274","GO:0042254","GO:0000462","GO:0043248","GO:0000469"]},{"accession":"XP_051394534.1","go_terms":[]},{"accession":"XP_051395122.1","go_terms":["GO:0000462"]},{"accession":"XP_051395402.1","go_terms":["GO:0034477","GO:0008380","GO:0030223","GO:0006397"]},{"accession":"XP_051395615.1","go_terms":["GO:0051384","GO:0042136","GO:0046340","GO:0050783","GO:0007612","GO:0030245","GO:0050808","GO:0060041","GO:0001507","GO:0090122","GO:0019441","GO:0014016","GO:0048444","GO:0051262","GO:0051791","GO:0008285","GO:0045212","GO:0043279","GO:0032223","GO:0031623","GO:0009740","GO:0051593","GO:0019695","GO:0042493","GO:0010325","GO:0006695","GO:0009939","GO:0001919","GO:0002076"]},{"accession":"XP_051393784.1","go_terms":["GO:0051402","GO:0016255"]},{"accession":"XP_051393565.1","go_terms":["GO:0006855","GO:0015739","GO:0015707","GO:0015706","GO:0071805","GO:0098700","GO:0035435","GO:1900754","GO:0042128","GO:0035725","GO:0015751","GO:0006004","GO:0042891","GO:0035461","GO:0015757"]},{"accession":"XP_051395098.1","go_terms":[]},{"accession":"XP_051389310.1","go_terms":[]}],"graph":[["XP_051395098.1","XP_051390103.1",0.749],["XP_051389619.1","XP_051393784.1",0.599],["XP_051390103.1","XP_051389310.1",0.892],["XP_051390103.1","XP_051393784.1",0.979],["XP_051389271.1","XP_051393784.1",0.582],["XP_051389271.1","XP_051389310.1",0.506],["XP_051394534.1","XP_051389310.1",0.656],["XP_051394534.1","XP_051393784.1",0.547],["XP_051395402.1","XP_051393784.1",0.529]],"all_go_terms":{"GO:0006616":1,"GO:0006614":1,"GO:0008285":2,"GO:0043065":1,"GO:0072520":1,"GO:0006978":1,"GO:0043968":1,"GO:0043982":1,"GO:2000873":1,"GO:0043983":1,"GO:0048133":1,"GO:0061408":1,"GO:0061186":1,"GO:2000219":1,"GO:2000772":1,"GO:0016479":1,"GO:0030511":1,"GO:0043981":1,"GO:0007141":1,"GO:0061188":1,"GO:0043966":1,"GO:0031065":1,"GO:1900404":1,"GO:0000462":2,"GO:0042254":1,"GO:0043248":1,"GO:0042274":1,"GO:0000469":1,"GO:0009553":1,"GO:0006397":1,"GO:0030223":1,"GO:0008380":1,"GO:0034477":1,"GO:0042493":1,"GO:0031623":1,"GO:0019695":1,"GO:0010325":1,"GO:0046340":1,"GO:0060041":1,"GO:0048444":1,"GO:0009939":1,"GO:0030245":1,"GO:0002076":1,"GO:0090122":1,"GO:0051384":1,"GO:0051791":1,"GO:0051262":1,"GO:0045212":1,"GO:0043279":1,"GO:0019441":1,"GO:0014016":1,"GO:0001507":1,"GO:0009740":1,"GO:0006695":1,"GO:0050808":1,"GO:0032223":1,"GO:0050783":1,"GO:0007612":1,"GO:0042136":1,"GO:0001919":1,"GO:0051593":1,"GO:0051402":1,"GO:0016255":1,"GO:1900754":1,"GO:0035461":1,"GO:0042891":1,"GO:0015707":1,"GO:0071805":1,"GO:0015757":1,"GO:0015739":1,"GO:0006004":1,"GO:0035725":1,"GO:0015751":1,"GO:0015706":1,"GO:0035435":1,"GO:0098700":1,"GO:0042128":1,"GO:0006855":1},"recipe_readded":["XP_051391414.1","XP_051391335.1","XP_051388792.1","XP_051389215.1","XP_051394346.1","XP_051391882.1","XP_051391747.1","XP_051390890.1","XP_051388916.1","XP_051389995.1","XP_051391151.1","XP_051394875.1","XP_051391664.1","XP_051389827.1","XP_051395566.1","XP_051390482.1","XP_051395429.1","XP_051394491.1","XP_051389976.1","XP_051392657.1"]}