{"hash":"353282977445285901","title":"Ribosome biogenesis and translation machinery","description":"The cluster is dominated by GO terms related to ribosome assembly and function\u2014translation, ribosome biogenesis, rRNA processing, and ribosomal large subunit biogenesis\u2014along with rRNA modification (pseudouridine synthesis) and tRNA aminoacylation, plus translational fidelity maintenance. This points to proteins involved in ribosome maturation, rRNA/tRNA processing, and translation accuracy. A few ancillary terms (transcription, heat response) are less central. Overall, the group reflects core ribosome/translation processes.","confidence":"High","size":7,"edges":21,"triangles":35,"max_degree":6,"top_function":"ribosome biogenesis","members":[{"accession":"XP_051388683.1","go_terms":["GO:0031564","GO:0045903","GO:0006353","GO:0006412","GO:1990145","GO:0046677","GO:0006351","GO:0045947","GO:0006437","GO:0034605","GO:0000455","GO:0042254"]},{"accession":"XP_051389319.1","go_terms":["GO:0000185","GO:2000623","GO:0031118","GO:0031120","GO:0046330","GO:0007338","GO:0000470","GO:0048025","GO:0042254","GO:0001682","GO:1900745","GO:1904571","GO:0000492","GO:0006412"]},{"accession":"XP_051390087.1","go_terms":["GO:0034724","GO:0030574","GO:0034396","GO:0035551"]},{"accession":"XP_051390368.1","go_terms":["GO:0042273","GO:0006364","GO:0016236","GO:0006412","GO:0051298","GO:0042256"]},{"accession":"XP_051390669.1","go_terms":["GO:0006468","GO:2000208","GO:0060252","GO:0000462","GO:0046830","GO:2000234"]},{"accession":"XP_051392193.1","go_terms":["GO:0006364"]},{"accession":"XP_051392805.1","go_terms":["GO:0042273","GO:0000055","GO:0042254","GO:0030036","GO:0007089","GO:0007049"]}],"graph":[["XP_051388683.1","XP_051389319.1",0.88],["XP_051388683.1","XP_051390087.1",0.918],["XP_051388683.1","XP_051390368.1",0.955],["XP_051388683.1","XP_051390669.1",0.876],["XP_051388683.1","XP_051392193.1",0.896],["XP_051388683.1","XP_051392805.1",0.846],["XP_051392193.1","XP_051389319.1",0.868],["XP_051392193.1","XP_051390087.1",0.965],["XP_051392193.1","XP_051390368.1",0.876],["XP_051392193.1","XP_051390669.1",0.883],["XP_051392193.1","XP_051392805.1",0.711],["XP_051390669.1","XP_051389319.1",0.907],["XP_051390669.1","XP_051390087.1",0.958],["XP_051390669.1","XP_051390368.1",0.909],["XP_051390669.1","XP_051392805.1",0.861],["XP_051390368.1","XP_051389319.1",0.883],["XP_051390368.1","XP_051390087.1",0.961],["XP_051390368.1","XP_051392805.1",0.813],["XP_051390087.1","XP_051389319.1",0.961],["XP_051390087.1","XP_051392805.1",0.963],["XP_051389319.1","XP_051392805.1",0.83]],"all_go_terms":{"GO:1990145":1,"GO:0000455":1,"GO:0034605":1,"GO:0045903":1,"GO:0006351":1,"GO:0006437":1,"GO:0006353":1,"GO:0006412":3,"GO:0042254":3,"GO:0046677":1,"GO:0031564":1,"GO:0045947":1,"GO:0048025":1,"GO:1900745":1,"GO:2000623":1,"GO:0031120":1,"GO:0001682":1,"GO:0000185":1,"GO:0007338":1,"GO:0000492":1,"GO:0046330":1,"GO:0031118":1,"GO:0000470":1,"GO:1904571":1,"GO:0035551":1,"GO:0034396":1,"GO:0030574":1,"GO:0034724":1,"GO:0051298":1,"GO:0016236":1,"GO:0042256":1,"GO:0006364":2,"GO:0042273":2,"GO:0006468":1,"GO:0000462":1,"GO:0060252":1,"GO:2000208":1,"GO:0046830":1,"GO:2000234":1,"GO:0007049":1,"GO:0000055":1,"GO:0030036":1,"GO:0007089":1},"recipe_readded":[]}