{"hash":"1240736040403229548","title":"Ubiquitin-mediated proteolysis and chromatin modification","description":"The top GO terms cluster around ubiquitin pathways: SCF complex assembly, ubiquitin-dependent protein catabolic processes via multivesicular body sorting, and histone H2A K63-linked ubiquitination, plus a histone H4-K16 acetylation term. This points to a shared theme of ubiquitin signaling regulating protein turnover and chromatin state. Other terms (viral process, TNF signaling, V(D)J recombination) are less representative and appear as isolated annotations. Overall, the main signal is ubiquitin-dependent regulation. ","confidence":"Medium","size":3,"edges":2,"triangles":0,"max_degree":2,"top_function":null,"members":[{"accession":"XP_051390143.1","go_terms":["GO:0038018","GO:0016558","GO:0030433","GO:0060816","GO:0051865","GO:0042787","GO:0046621","GO:1900095","GO:0070936","GO:0006295","GO:0006294","GO:0006296","GO:0045116","GO:0010265","GO:0043162","GO:0000717","GO:0006293","GO:0000715","GO:0016567","GO:1902104","GO:0042769","GO:0016032","GO:0051759","GO:0031146","GO:0070911","GO:0039536","GO:0002250","GO:0033151","GO:0033209","GO:0009048","GO:0036205","GO:0046328","GO:2000620","GO:0042981","GO:0007250","GO:0070512","GO:0085020","GO:0070535","GO:1903265","GO:1903762","GO:1903721","GO:1901253","GO:0090073"]},{"accession":"XP_051388395.1","go_terms":["GO:1990758","GO:0031116","GO:0051987"]},{"accession":"XP_051393387.1","go_terms":[]}],"graph":[["XP_051393387.1","XP_051388395.1",0.815],["XP_051393387.1","XP_051390143.1",0.607]],"all_go_terms":{"GO:0010265":1,"GO:0043162":1,"GO:0070535":1,"GO:1903762":1,"GO:0016032":1,"GO:2000620":1,"GO:0033209":1,"GO:0033151":1,"GO:0060816":1,"GO:1901253":1,"GO:0036205":1,"GO:0090073":1,"GO:0000715":1,"GO:0070512":1,"GO:0030433":1,"GO:1902104":1,"GO:0031146":1,"GO:0000717":1,"GO:0016558":1,"GO:0009048":1,"GO:0045116":1,"GO:0038018":1,"GO:0042787":1,"GO:0006295":1,"GO:0006293":1,"GO:0042769":1,"GO:0070911":1,"GO:0085020":1,"GO:0051759":1,"GO:1903265":1,"GO:1900095":1,"GO:0070936":1,"GO:1903721":1,"GO:0007250":1,"GO:0046621":1,"GO:0006294":1,"GO:0051865":1,"GO:0046328":1,"GO:0002250":1,"GO:0006296":1,"GO:0016567":1,"GO:0042981":1,"GO:0039536":1,"GO:0031116":1,"GO:1990758":1,"GO:0051987":1},"recipe_readded":[]}