{"hash":"936305371604169719","title":"Cytoskeletal transport and proteostasis under stress","description":"The dominant terms point to microtubule dynamics (GO:0031109), anterograde axonal transport (GO:0099641), and regulation of intracellular transport (GO:0032387), plus protein stabilization (GO:0050821) and stress responses (GO:0042542, GO:0042542; GO:1900034). Lens fiber morphogenesis (GO:0070309) and negative regulation of amyloid fibril formation (GO:1905907) suggest proteostasis in specialized tissues like lens and neurons. Together, they indicate a module coordinating cytoskeleton, trafficking, and protein homeostasis under stress.","confidence":"Medium","size":8,"edges":22,"triangles":27,"max_degree":7,"top_function":null,"members":[{"accession":"XP_046442929.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0014823","GO:0042493","GO:0042413","GO:0046676","GO:0032868","GO:0006574","GO:0019521","GO:0006096","GO:0045454"]},{"accession":"XP_046449505.1","go_terms":["GO:0048575","GO:0030154","GO:0060409","GO:0042755","GO:0010229","GO:0010951","GO:0048240","GO:0007275","GO:0009911","GO:0009910","GO:0048510","GO:0009908"]},{"accession":"XP_046452580.1","go_terms":["GO:0099641","GO:0071480","GO:0032387","GO:0050821","GO:0032355","GO:0009644","GO:0030308","GO:0032463","GO:2000378","GO:0070309","GO:0006936","GO:0070141","GO:0031109","GO:0009408","GO:0007568","GO:0042542","GO:1900034","GO:0051403","GO:1905907"]},{"accession":"XP_046454283.1","go_terms":["GO:0034724","GO:0030574","GO:0034396","GO:0035551"]},{"accession":"XP_046454750.1","go_terms":["GO:0043547","GO:0019079","GO:0001172","GO:0046677","GO:0006414","GO:0006412"]},{"accession":"XP_046460699.1","go_terms":["GO:0099641","GO:0071480","GO:0032387","GO:0050821","GO:0032355","GO:0009644","GO:0030308","GO:0032463","GO:2000378","GO:0070309","GO:0006936","GO:0070141","GO:0031109","GO:0009408","GO:0007568","GO:0042542","GO:1900034","GO:0051403","GO:1905907"]},{"accession":"XP_046460702.1","go_terms":["GO:0099641","GO:0071480","GO:0032387","GO:0050821","GO:0032355","GO:0009644","GO:0030308","GO:0032463","GO:2000378","GO:0070309","GO:0006936","GO:0070141","GO:0031109","GO:0009408","GO:0007568","GO:0042542","GO:1900034","GO:0051403","GO:1905907"]},{"accession":"XP_046447032.1","go_terms":["GO:0001702","GO:0040025","GO:0042121","GO:0009246","GO:0036460","GO:0006011","GO:0006065","GO:0055114","GO:0006024","GO:0046168","GO:0006813","GO:0014823","GO:0006099","GO:0046676","GO:0032868","GO:0045454","GO:0042493"]}],"graph":[["XP_046447032.1","XP_046449505.1",0.53],["XP_046447032.1","XP_046452580.1",0.565],["XP_046447032.1","XP_046460699.1",0.78],["XP_046447032.1","XP_046460702.1",0.962],["XP_046449505.1","XP_046442929.1",0.944],["XP_046449505.1","XP_046454750.1",0.875],["XP_046449505.1","XP_046454283.1",0.921],["XP_046449505.1","XP_046452580.1",0.976],["XP_046449505.1","XP_046460702.1",0.842],["XP_046460699.1","XP_046442929.1",0.979],["XP_046460699.1","XP_046452580.1",0.908],["XP_046460699.1","XP_046454750.1",0.635],["XP_046460699.1","XP_046460702.1",0.923],["XP_046452580.1","XP_046442929.1",0.966],["XP_046452580.1","XP_046454283.1",0.909],["XP_046452580.1","XP_046454750.1",0.948],["XP_046452580.1","XP_046460702.1",0.969],["XP_046442929.1","XP_046454750.1",0.978],["XP_046442929.1","XP_046454283.1",0.941],["XP_046442929.1","XP_046460702.1",0.988],["XP_046454283.1","XP_046454750.1",0.888],["XP_046460702.1","XP_046454750.1",0.926]],"all_go_terms":{"GO:0014823":2,"GO:0009234":1,"GO:0006635":1,"GO:0006574":1,"GO:0046676":2,"GO:0042372":1,"GO:0019521":1,"GO:0042413":1,"GO:0042493":2,"GO:0045454":2,"GO:0032868":2,"GO:0010124":1,"GO:0006096":1,"GO:0017000":1,"GO:0048240":1,"GO:0060409":1,"GO:0009910":1,"GO:0007275":1,"GO:0010951":1,"GO:0009911":1,"GO:0048575":1,"GO:0009908":1,"GO:0042755":1,"GO:0048510":1,"GO:0010229":1,"GO:0030154":1,"GO:1905907":3,"GO:0099641":3,"GO:0070309":3,"GO:0031109":3,"GO:1900034":3,"GO:0007568":3,"GO:0032387":3,"GO:0050821":3,"GO:0042542":3,"GO:0032463":3,"GO:0009408":3,"GO:0030308":3,"GO:0070141":3,"GO:0032355":3,"GO:2000378":3,"GO:0009644":3,"GO:0071480":3,"GO:0006936":3,"GO:0051403":3,"GO:0030574":1,"GO:0035551":1,"GO:0034396":1,"GO:0034724":1,"GO:0006412":1,"GO:0006414":1,"GO:0046677":1,"GO:0043547":1,"GO:0001172":1,"GO:0019079":1,"GO:0009246":1,"GO:0006813":1,"GO:0001702":1,"GO:0040025":1,"GO:0006065":1,"GO:0046168":1,"GO:0006099":1,"GO:0042121":1,"GO:0006024":1,"GO:0006011":1,"GO:0055114":1,"GO:0036460":1},"recipe_readded":[]}