{"hash":"30191416975338036","title":"Development and Chromatin Regulation","description":"This cluster centers on proteins associated with developmental processes (larval chitin-based cuticle development; animal organ development; regulation of cell proliferation in development) and chromatin-level control (histone acetylation, histone demethylation, heterochromatin formation, transcriptional regulation). While a peripheral immune tolerance term appears, the dominant signal ties development to chromatin regulation, suggesting roles in controlling developmental gene expression programs.","confidence":"Medium","size":18,"edges":70,"triangles":101,"max_degree":14,"top_function":null,"members":[{"accession":"XP_046453501.1","go_terms":["GO:0043972","GO:0034720","GO:0002509","GO:0032602","GO:0097190","GO:0007098","GO:1901536","GO:0098532","GO:0051569","GO:0002458","GO:0090308","GO:2000791","GO:0010216","GO:0000122","GO:0045869","GO:0051225","GO:0097536","GO:0048513","GO:0070562","GO:0080182","GO:2001040","GO:2000864","GO:0060669","GO:1901097","GO:0007289","GO:1901726","GO:0006334","GO:1901674","GO:1904388","GO:0061087","GO:0061086","GO:0044648","GO:2000584","GO:0061188","GO:2000410","GO:0048655"]},{"accession":"XP_046454363.1","go_terms":[]},{"accession":"XP_046457173.1","go_terms":[]},{"accession":"XP_046437802.1","go_terms":["GO:0045292","GO:0042254","GO:1903955","GO:0001522","GO:1903146"]},{"accession":"XP_046438354.1","go_terms":["GO:2001256","GO:0006816"]},{"accession":"XP_046440502.1","go_terms":["GO:0002028"]},{"accession":"XP_046440589.1","go_terms":["GO:0017183","GO:0007117","GO:0002098"]},{"accession":"XP_046440606.1","go_terms":[]},{"accession":"XP_046440916.1","go_terms":["GO:0008363"]},{"accession":"XP_046444281.1","go_terms":[]},{"accession":"XP_046449800.1","go_terms":[]},{"accession":"XP_046452457.1","go_terms":["GO:0007221","GO:0007219","GO:0003162","GO:0007475","GO:0007418","GO:0060928","GO:0010831","GO:0045445","GO:0007500"]},{"accession":"XP_046453686.1","go_terms":["GO:0008363"]},{"accession":"XP_046455666.1","go_terms":[]},{"accession":"XP_046456365.1","go_terms":[]},{"accession":"XP_046460386.1","go_terms":[]},{"accession":"XP_046446860.1","go_terms":[]},{"accession":"XP_046462632.1","go_terms":["GO:0008363"]}],"graph":[["XP_046440589.1","XP_046437802.1",0.543],["XP_046440589.1","XP_046438354.1",0.625],["XP_046440589.1","XP_046440502.1",0.621],["XP_046440589.1","XP_046440606.1",0.748],["XP_046440589.1","XP_046453686.1",0.748],["XP_046440589.1","XP_046454363.1",0.514],["XP_046440916.1","XP_046437802.1",0.583],["XP_046440916.1","XP_046440502.1",0.515],["XP_046440916.1","XP_046440606.1",0.608],["XP_046440916.1","XP_046452457.1",0.525],["XP_046440916.1","XP_046454363.1",0.667],["XP_046440916.1","XP_046455666.1",0.59],["XP_046440916.1","XP_046460386.1",0.693],["XP_046457173.1","XP_046437802.1",0.684],["XP_046457173.1","XP_046440502.1",0.583],["XP_046457173.1","XP_046454363.1",0.639],["XP_046457173.1","XP_046455666.1",0.53],["XP_046453501.1","XP_046437802.1",0.546],["XP_046453501.1","XP_046440606.1",0.596],["XP_046453501.1","XP_046444281.1",0.563],["XP_046453501.1","XP_046455666.1",0.625],["XP_046437802.1","XP_046444281.1",0.696],["XP_046437802.1","XP_046440606.1",0.623],["XP_046437802.1","XP_046438354.1",0.604],["XP_046437802.1","XP_046452457.1",0.668],["XP_046437802.1","XP_046449800.1",0.711],["XP_046437802.1","XP_046446860.1",0.653],["XP_046437802.1","XP_046462632.1",0.501],["XP_046437802.1","XP_046460386.1",0.807],["XP_046437802.1","XP_046455666.1",0.625],["XP_046440502.1","XP_046446860.1",0.662],["XP_046440502.1","XP_046452457.1",0.712],["XP_046440502.1","XP_046453686.1",0.595],["XP_046440502.1","XP_046455666.1",0.675],["XP_046440502.1","XP_046462632.1",0.65],["XP_046444281.1","XP_046446860.1",0.521],["XP_046444281.1","XP_046449800.1",0.75],["XP_046444281.1","XP_046455666.1",0.783],["XP_046444281.1","XP_046460386.1",0.768],["XP_046444281.1","XP_046462632.1",0.693],["XP_046449800.1","XP_046438354.1",0.538],["XP_046449800.1","XP_046440606.1",0.722],["XP_046449800.1","XP_046452457.1",0.54],["XP_046449800.1","XP_046462632.1",0.652],["XP_046449800.1","XP_046460386.1",0.853],["XP_046449800.1","XP_046455666.1",0.503],["XP_046452457.1","XP_046440606.1",0.549],["XP_046452457.1","XP_046454363.1",0.521],["XP_046452457.1","XP_046462632.1",0.58],["XP_046452457.1","XP_046460386.1",0.67],["XP_046452457.1","XP_046455666.1",0.718],["XP_046438354.1","XP_046440606.1",0.734],["XP_046438354.1","XP_046454363.1",0.761],["XP_046455666.1","XP_046440606.1",0.562],["XP_046455666.1","XP_046446860.1",0.644],["XP_046455666.1","XP_046454363.1",0.544],["XP_046455666.1","XP_046456365.1",0.525],["XP_046455666.1","XP_046460386.1",0.592],["XP_046455666.1","XP_046462632.1",0.716],["XP_046446860.1","XP_046453686.1",0.799],["XP_046446860.1","XP_046456365.1",0.869],["XP_046446860.1","XP_046460386.1",0.76],["XP_046446860.1","XP_046462632.1",0.826],["XP_046460386.1","XP_046440606.1",0.713],["XP_046460386.1","XP_046456365.1",0.825],["XP_046460386.1","XP_046462632.1",0.772],["XP_046456365.1","XP_046462632.1",0.828],["XP_046453686.1","XP_046440606.1",0.592],["XP_046453686.1","XP_046462632.1",0.59],["XP_046454363.1","XP_046440606.1",0.646]],"all_go_terms":{"GO:0061188":1,"GO:0048513":1,"GO:0043972":1,"GO:0002458":1,"GO:2001040":1,"GO:1901674":1,"GO:1904388":1,"GO:2000791":1,"GO:0034720":1,"GO:2000410":1,"GO:0061086":1,"GO:0006334":1,"GO:1901536":1,"GO:0051569":1,"GO:0044648":1,"GO:1901726":1,"GO:0051225":1,"GO:0002509":1,"GO:0097190":1,"GO:0080182":1,"GO:0048655":1,"GO:0070562":1,"GO:1901097":1,"GO:0060669":1,"GO:0007289":1,"GO:0097536":1,"GO:0098532":1,"GO:0090308":1,"GO:0045869":1,"GO:2000864":1,"GO:0000122":1,"GO:0007098":1,"GO:0010216":1,"GO:2000584":1,"GO:0032602":1,"GO:0061087":1,"GO:0001522":1,"GO:0045292":1,"GO:0042254":1,"GO:1903955":1,"GO:1903146":1,"GO:2001256":1,"GO:0006816":1,"GO:0002028":1,"GO:0017183":1,"GO:0007117":1,"GO:0002098":1,"GO:0008363":3,"GO:0045445":1,"GO:0060928":1,"GO:0007221":1,"GO:0007475":1,"GO:0010831":1,"GO:0007219":1,"GO:0003162":1,"GO:0007418":1,"GO:0007500":1},"recipe_readded":[]}