{"hash":"23537082087047776","title":"Membrane trafficking and mitochondrial dynamics","description":"This cluster centers on membrane-associated processes and mitochondrial function: terms such as inner mitochondrial membrane organization, mitochondrial membrane potential, and stress-induced mitochondrial fusion point to mitochondrial dynamics, while protein localization to membrane rafts and SREBP signaling relate to membrane organization and lipid signaling. Other terms like positive regulation of cell adhesion molecule production and metanephric podocyte development suggest membrane/cell-surface dynamics in specialized cell types, and ubiquitin-dependent ERAD pathway plus excretion reflect membrane-anchored protein quality control and transport. Overall, the common theme is interplay between membrane organization and mitochondrial dynamics shaping cellular trafficking and signaling.","confidence":"Medium","size":11,"edges":55,"triangles":165,"max_degree":10,"top_function":null,"members":[{"accession":"XP_046441498.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]},{"accession":"XP_046452351.1","go_terms":["GO:0030307","GO:0006713","GO:0021766","GO:0048167","GO:0021762","GO:0010482","GO:0032869","GO:0034766","GO:0071901","GO:0090168","GO:0046827","GO:0042921","GO:0021987","GO:0001764","GO:1900740","GO:0043588","GO:0030216","GO:0051291","GO:1902309","GO:0006605","GO:0006977","GO:0086010","GO:0010839","GO:0008630","GO:0031424","GO:0000079","GO:0003334","GO:0001836","GO:0043154","GO:0051683"]},{"accession":"XP_046443225.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]},{"accession":"XP_046453924.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]},{"accession":"XP_046453927.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]},{"accession":"XP_046453928.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]},{"accession":"XP_046453929.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]},{"accession":"XP_046455287.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]},{"accession":"XP_046455291.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]},{"accession":"XP_046455826.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]},{"accession":"XP_046455828.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]}],"graph":[["XP_046453927.1","XP_046441498.1",0.944],["XP_046453927.1","XP_046443225.1",0.942],["XP_046453927.1","XP_046452351.1",0.917],["XP_046453927.1","XP_046453924.1",0.936],["XP_046453927.1","XP_046453928.1",0.912],["XP_046453927.1","XP_046453929.1",0.951],["XP_046453927.1","XP_046455287.1",0.915],["XP_046453927.1","XP_046455291.1",0.926],["XP_046453927.1","XP_046455826.1",0.935],["XP_046453927.1","XP_046455828.1",0.948],["XP_046441498.1","XP_046443225.1",0.973],["XP_046441498.1","XP_046452351.1",0.92],["XP_046441498.1","XP_046453924.1",0.949],["XP_046441498.1","XP_046453928.1",0.953],["XP_046441498.1","XP_046453929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