{"hash":"2156221270666516070","title":"Mitochondrial energy metabolism and metal homeostasis","description":"The cluster centers on mitochondrial processes: assembly of respiratory chain complex IV, ATP regulation, redox homeostasis, and copper/heme cofactor pathways. Copper ion transport and intracellular copper homeostasis support cytochrome c oxidase function, while heme biosynthesis and mitochondrial translation fit with mitochondrial biology, suggesting a cohesive theme of mitochondrial energy metabolism and metal cofactor management. Some terms (erythrocyte differentiation, oocyte construction) are less directly related but do not override the core mitochondrial signal.","confidence":"Medium","size":10,"edges":45,"triangles":120,"max_degree":9,"top_function":null,"members":[{"accession":"XP_046437308.1","go_terms":[]},{"accession":"XP_046441026.1","go_terms":["GO:0006878","GO:0008535","GO:0006825","GO:0007308","GO:0045454"]},{"accession":"XP_046446822.1","go_terms":["GO:0030218","GO:0051882","GO:0032780","GO:1904925","GO:1903578","GO:1903214","GO:1901030","GO:0006783","GO:0001937"]},{"accession":"XP_046450892.1","go_terms":["GO:0009236","GO:0006541","GO:0018108","GO:0051782","GO:0045226","GO:0007049","GO:0009103","GO:0002098","GO:0016226","GO:0030541","GO:0006859","GO:0007059"]},{"accession":"XP_046451108.1","go_terms":[]},{"accession":"XP_046458125.1","go_terms":["GO:0002181","GO:1990090","GO:0032543"]},{"accession":"XP_046459149.1","go_terms":[]},{"accession":"XP_046459475.1","go_terms":["GO:0017148","GO:0042255","GO:0060702","GO:0046677","GO:0006351","GO:0006353","GO:0006412"]},{"accession":"XP_046462656.1","go_terms":["GO:1904960","GO:0033132","GO:0008535"]},{"accession":"XP_046464128.1","go_terms":["GO:0071353","GO:0006412","GO:0000027"]}],"graph":[["XP_046446822.1","XP_046437308.1",0.977],["XP_046446822.1","XP_046441026.1",0.984],["XP_046446822.1","XP_046450892.1",0.976],["XP_046446822.1","XP_046451108.1",0.98],["XP_046446822.1","XP_046458125.1",0.972],["XP_046446822.1","XP_046459149.1",0.963],["XP_046446822.1","XP_046459475.1",0.981],["XP_046446822.1","XP_046462656.1",0.973],["XP_046446822.1","XP_046464128.1",0.979],["XP_046450892.1","XP_046437308.1",0.989],["XP_046450892.1","XP_046441026.1",0.925],["XP_046450892.1","XP_046451108.1",0.966],["XP_046450892.1","XP_046458125.1",0.944],["XP_046450892.1","XP_046459149.1",0.99],["XP_046450892.1","XP_046459475.1",0.969],["XP_046450892.1","XP_046462656.1",0.965],["XP_046450892.1","XP_046464128.1",0.915],["XP_046459149.1","XP_046437308.1",0.983],["XP_046459149.1","XP_046441026.1",0.989],["XP_046459149.1","XP_046451108.1",0.979],["XP_046459149.1","XP_046458125.1",0.99],["XP_046459149.1","XP_046459475.1",0.98],["XP_046459149.1","XP_046462656.1",0.985],["XP_046459149.1","XP_046464128.1",0.99],["XP_046451108.1","XP_046437308.1",0.975],["XP_046451108.1","XP_046441026.1",0.989],["XP_046451108.1","XP_046458125.1",0.948],["XP_046451108.1","XP_046459475.1",0.98],["XP_046451108.1","XP_046462656.1",0.988],["XP_046451108.1","XP_046464128.1",0.919],["XP_046462656.1","XP_046437308.1",0.985],["XP_046462656.1","XP_046441026.1",0.989],["XP_046462656.1","XP_046458125.1",0.989],["XP_046462656.1","XP_046459475.1",0.983],["XP_046462656.1","XP_046464128.1",0.984],["XP_046459475.1","XP_046437308.1",0.965],["XP_046459475.1","XP_046441026.1",0.989],["XP_046459475.1","XP_046458125.1",0.966],["XP_046459475.1","XP_046464128.1",0.853],["XP_046464128.1","XP_046437308.1",0.99],["XP_046464128.1","XP_046441026.1",0.99],["XP_046464128.1","XP_046458125.1",0.902],["XP_046441026.1","XP_046437308.1",0.985],["XP_046441026.1","XP_046458125.1",0.99],["XP_046437308.1","XP_046458125.1",0.988]],"all_go_terms":{"GO:0007308":1,"GO:0006825":1,"GO:0045454":1,"GO:0008535":2,"GO:0006878":1,"GO:1903578":1,"GO:0030218":1,"GO:0032780":1,"GO:0006783":1,"GO:1904925":1,"GO:1903214":1,"GO:0001937":1,"GO:1901030":1,"GO:0051882":1,"GO:0002098":1,"GO:0006541":1,"GO:0045226":1,"GO:0007049":1,"GO:0006859":1,"GO:0030541":1,"GO:0051782":1,"GO:0009103":1,"GO:0009236":1,"GO:0016226":1,"GO:0007059":1,"GO:0018108":1,"GO:0002181":1,"GO:1990090":1,"GO:0032543":1,"GO:0006412":2,"GO:0006351":1,"GO:0046677":1,"GO:0017148":1,"GO:0006353":1,"GO:0042255":1,"GO:0060702":1,"GO:0033132":1,"GO:1904960":1,"GO:0071353":1,"GO:0000027":1},"recipe_readded":[]}