{"hash":"2052184898426562967","title":"Sumoylation-Linked Genome Maintenance","description":"The cluster centers on genome stability processes such as homologous recombination repair, meiotic chromosome alignment, and telomere maintenance, with a strong presence of protein sumoylation (autosumoylation, sumoylation). This suggests a functional module where SUMO modification regulates chromosome dynamics and DNA repair, with several additional terms indicating broader regulatory roles in development and signaling. Overall, the common thread is sumoylation-associated control of genome maintenance, despite some outlier developmental terms.","confidence":"Medium","size":18,"edges":20,"triangles":6,"max_degree":6,"top_function":null,"members":[{"accession":"XP_046442725.1","go_terms":["GO:0000722","GO:0090398","GO:0010082","GO:0000724","GO:0060250","GO:0080038","GO:0045842","GO:0032876","GO:1990683","GO:0071901","GO:0016925","GO:0034184","GO:1904333","GO:1902174","GO:1902231","GO:0010804","GO:0003007","GO:0007296","GO:0060766","GO:0016049","GO:1904290","GO:0043060","GO:0045838","GO:1990466","GO:0033235","GO:0033234"]},{"accession":"XP_046452685.1","go_terms":[]},{"accession":"XP_046456390.1","go_terms":["GO:0045451","GO:0000184","GO:0008103","GO:0007318","GO:0006397"]},{"accession":"XP_046454408.1","go_terms":[]},{"accession":"XP_046447527.1","go_terms":["GO:0008363"]},{"accession":"XP_046447530.1","go_terms":["GO:0008363"]},{"accession":"XP_046448057.1","go_terms":[]},{"accession":"XP_046454792.1","go_terms":["GO:0008363"]},{"accession":"XP_046456151.1","go_terms":[]},{"accession":"XP_046456705.1","go_terms":[]},{"accession":"XP_046460845.1","go_terms":[]},{"accession":"XP_046462494.1","go_terms":[]},{"accession":"XP_046443786.1","go_terms":[]},{"accession":"XP_046450628.1","go_terms":[]},{"accession":"XP_046460229.1","go_terms":[]},{"accession":"XP_046461302.1","go_terms":[]},{"accession":"XP_046461412.1","go_terms":[]},{"accession":"XP_046461433.1","go_terms":[]}],"graph":[["XP_046443786.1","XP_046442725.1",0.517],["XP_046443786.1","XP_046447527.1",0.681],["XP_046443786.1","XP_046448057.1",0.536],["XP_046443786.1","XP_046454792.1",0.566],["XP_046443786.1","XP_046461412.1",0.645],["XP_046443786.1","XP_046461433.1",0.755],["XP_046461412.1","XP_046442725.1",0.548],["XP_046462494.1","XP_046454408.1",0.84],["XP_046461433.1","XP_046442725.1",0.695],["XP_046461433.1","XP_046448057.1",0.709],["XP_046456151.1","XP_046460229.1",0.791],["XP_046456151.1","XP_046461302.1",0.564],["XP_046442725.1","XP_046448057.1",0.696],["XP_046448057.1","XP_046460229.1",0.765],["XP_046456705.1","XP_046454408.1",0.721],["XP_046456705.1","XP_046460229.1",0.504],["XP_046460229.1","XP_046447527.1",0.643],["XP_046460229.1","XP_046454408.1",0.616],["XP_046447527.1","XP_046452685.1",0.653],["XP_046454408.1","XP_046452685.1",0.731]],"all_go_terms":{"GO:0000724":1,"GO:0010082":1,"GO:0007296":1,"GO:0043060":1,"GO:0000722":1,"GO:0010804":1,"GO:1990466":1,"GO:0016925":1,"GO:0060766":1,"GO:0071901":1,"GO:0045842":1,"GO:0060250":1,"GO:1990683":1,"GO:1902174":1,"GO:1904333":1,"GO:0032876":1,"GO:0045838":1,"GO:0090398":1,"GO:0033235":1,"GO:0003007":1,"GO:1902231":1,"GO:1904290":1,"GO:0034184":1,"GO:0080038":1,"GO:0016049":1,"GO:0033234":1,"GO:0000184":1,"GO:0006397":1,"GO:0007318":1,"GO:0045451":1,"GO:0008103":1,"GO:0008363":3},"recipe_readded":[]}