{"hash":"1152817763947612460","title":"Ubiquitin-Proteasome Proteostasis in Insect Development","description":"The cluster heavily features ubiquitin-proteasome\u2013linked proteolysis and protein quality control terms (e.g., ubiquitin-dependent catabolic process, nuclear quality control), pointing to a proteostasis module. It also includes insect-development terms (larval cuticle development, photoreceptor organization), suggesting this proteostasis machinery supports developmental processes in insects. Some terms are obsolete or broad, but the overall theme links regulated protein turnover to insect development.","confidence":"Medium","size":28,"edges":339,"triangles":2455,"max_degree":27,"top_function":null,"members":[{"accession":"XP_046453945.1","go_terms":["GO:0008363"]},{"accession":"XP_046453947.1","go_terms":["GO:0008363"]},{"accession":"XP_046453951.1","go_terms":["GO:0008363"]},{"accession":"XP_046453952.1","go_terms":["GO:0008363"]},{"accession":"XP_046453957.1","go_terms":["GO:0008363"]},{"accession":"XP_046454048.1","go_terms":["GO:0008363"]},{"accession":"XP_046454051.1","go_terms":["GO:0008363"]},{"accession":"XP_046455372.1","go_terms":["GO:0008363"]},{"accession":"XP_046462513.1","go_terms":[]},{"accession":"XP_046462516.1","go_terms":[]},{"accession":"XP_046441976.1","go_terms":[]},{"accession":"XP_046462376.1","go_terms":[]},{"accession":"XP_046439389.1","go_terms":["GO:0071357","GO:0030850","GO:0046661","GO:0006463","GO:0050689","GO:0071360","GO:0045087","GO:0008277","GO:0051301","GO:0000492","GO:0001041","GO:0070206","GO:0006452","GO:0090084","GO:0006458","GO:0031204","GO:0006986","GO:0071374","GO:0001707","GO:0070843","GO:1901621","GO:0006260","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0006626","GO:0030433","GO:0009408","GO:0045454","GO:0036494","GO:0051259","GO:1900035","GO:0046825","GO:0035719","GO:0071630","GO:0034975","GO:0051348","GO:0000278","GO:0045842","GO:0034454","GO:0021756","GO:0046548","GO:0060613","GO:1903546","GO:0038108","GO:0090526","GO:0003085","GO:0060296","GO:0061087","GO:0035845","GO:1903646","GO:1905515","GO:1902855","GO:0070979","GO:0042787","GO:0007091","GO:0006478","GO:0016570","GO:2001162","GO:0035457","GO:1903071","GO:0031145","GO:0051607","GO:1902391","GO:2000324","GO:0015979","GO:0000413","GO:0009736","GO:0035955","GO:0016576","GO:1902325","GO:1903070","GO:0010288","GO:0070301","GO:0051291","GO:2000531","GO:0071276","GO:0043278","GO:1901215","GO:0031400","GO:0009938"]},{"accession":"XP_046443960.1","go_terms":["GO:0044829","GO:0043488","GO:1900363","GO:0034052","GO:1903679"]},{"accession":"XP_046451664.1","go_terms":[]},{"accession":"XP_046454307.1","go_terms":["GO:0008363"]},{"accession":"XP_046454697.1","go_terms":["GO:0008363"]},{"accession":"XP_046455921.1","go_terms":["GO:0008363"]},{"accession":"XP_046457224.1","go_terms":["GO:0008363"]},{"accession":"XP_046457225.1","go_terms":["GO:0008363"]},{"accession":"XP_046457346.1","go_terms":["GO:0008363"]},{"accession":"XP_046457443.1","go_terms":["GO:0008363"]},{"accession":"XP_046458875.1","go_terms":["GO:0008363"]},{"accession":"XP_046460423.1","go_terms":[]},{"accession":"XP_046463889.1","go_terms":[]},{"accession":"XP_046463893.1","go_terms":[]},{"accession":"XP_046463896.1","go_terms":[]},{"accession":"XP_046463901.1","go_terms":[]}],"graph":[["XP_046462516.1","XP_046439389.1",0.858],["XP_046462516.1","XP_046441976.1",0.805],["XP_046462516.1","XP_046443960.1",0.782],["XP_046462516.1","XP_046451664.1",0.609],["XP_046462516.1","XP_046453945.1",0.505],["XP_046462516.1","XP_046453947.1",0.595],["XP_046462516.1","XP_046453951.1",0.716],["XP_046462516.1","XP_046453952.1",0.616],["XP_046462516.1","XP_046453957.1",0.68],["XP_046462516.1","XP_046454048.1",0.703],["XP_046462516.1","XP_046454051.1",0.62],["XP_046462516.1","XP_046454307.1",0.677],["XP_046462516.1","XP_046454697.1",0.652],["XP_046462516.1","XP_046455921.1",0.719],["XP_046462516.1","XP_046457224.1",0.66],["XP_046462516.1","XP_046457225.1",0.749],["XP_046462516.1","XP_046457346.1",0.724],["XP_046462516.1","XP_046457443.1",0.645],["XP_046462516.1","XP_046458875.1",0.675],["XP_046462516.1","XP_046460423.1",0.591],["XP_046462516.1","XP_046463889.1",0.747],["XP_046462516.1","XP_046463893.1",0.801],["XP_046462516.1","XP_046463896.1",0.786],["XP_046462516.1","XP_046463901.1",0.821],["XP_046462516.1","XP_046462376.1",0.552],["XP_046453957.1","XP_046439389.1",0.77],["XP_046453957.1","XP_046441976.1",0.784],["XP_046453957.1","XP_046443960.1",0.775],["XP_046453957.1","XP_046453945.1",0.68],["XP_046453957.1","XP_046453947.1",0.679],["XP_046453957.1","XP_046453951.1",0.784],["XP_046453957.1","XP_046453952.1",0.824],["XP_046453957.1","XP_046454048.1",0.725],["XP_046453957.1","XP_046454051.1",0.893],["XP_046453957.1","XP_046454307.1",0.664],["XP_046453957.1","XP_046454697.1",0.509],["XP_046453957.1","XP_046455372.1",0.684],["XP_046453957.1","XP_046463889.1",0.732],["XP_046453957.1","XP_046463893.1",0.72],["XP_046453957.1","XP_046463896.1",0.697],["XP_046453957.1","XP_046463901.1",0.694],["XP_046453957.1","XP_046462376.1",0.674],["XP_046453957.1","XP_046462513.1",0.603],["XP_046453957.1","XP_046457346.1",0.615],["XP_046453957.1","XP_046457443.1",0.724],["XP_046453957.1","XP_046457224.1",0.606],["XP_046453957.1","XP_046457225.1",0.749],["XP_046453957.1","XP_046455921.1",0.846],["XP_046454051.1","XP_046439389.1",0.878],["XP_046454051.1","XP_046441976.1",0.786],["XP_046454051.1","XP_046443960.1",0.804],["XP_046454051.1","XP_046453945.1",0.758],["XP_046454051.1","XP_046453947.1",0.765],["XP_046454051.1","XP_046453951.1",0.812],["XP_046454051.1","XP_046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