{"hash":"426227040175239646","title":"Metabolic Regulation and Stress Signaling","description":"The cluster includes core metabolism terms (TCA cycle, oxaloacetate, glyoxylate cycle, NADH) alongside stress and signaling responses (estrogen, cAMP, hydrogen peroxide, nutrient response) and apoptosis regulation, suggesting a group coordinating energy metabolism with cellular stress signaling.","confidence":"Medium","size":9,"edges":35,"triangles":77,"max_degree":8,"top_function":null,"members":[{"accession":"XP_045402367.1","go_terms":["GO:0080093","GO:0048569","GO:0007584","GO:0006734","GO:0006099","GO:0051591","GO:0043627","GO:0006097","GO:0006096","GO:0001666","GO:0042542","GO:0042493","GO:0006107","GO:0009749","GO:0043065","GO:0055114","GO:0019244","GO:0006108"]},{"accession":"XP_045409990.1","go_terms":["GO:0080093","GO:0048569","GO:0007584","GO:0006734","GO:0006099","GO:0051591","GO:0043627","GO:0006097","GO:0006096","GO:0001666","GO:0042542","GO:0042493","GO:0006107","GO:0009749","GO:0043065","GO:0055114","GO:0019244","GO:0006108"]},{"accession":"XP_045410177.1","go_terms":["GO:0080093","GO:0048569","GO:0007584","GO:0006734","GO:0006099","GO:0051591","GO:0043627","GO:0006097","GO:0006096","GO:0001666","GO:0042542","GO:0042493","GO:0006107","GO:0009749","GO:0043065","GO:0055114","GO:0019244","GO:0006108"]},{"accession":"XP_045413606.1","go_terms":["GO:0080093","GO:0048569","GO:0007584","GO:0006734","GO:0006099","GO:0051591","GO:0043627","GO:0006097","GO:0006096","GO:0001666","GO:0042542","GO:0042493","GO:0006107","GO:0009749","GO:0043065","GO:0055114","GO:0019244","GO:0006108"]},{"accession":"XP_045413603.1","go_terms":["GO:0080093","GO:0048569","GO:0007584","GO:0006734","GO:0006099","GO:0051591","GO:0043627","GO:0006097","GO:0006096","GO:0001666","GO:0042542","GO:0042493","GO:0006107","GO:0009749","GO:0043065","GO:0055114","GO:0019244","GO:0006108"]},{"accession":"XP_045424047.1","go_terms":["GO:0006556","GO:0006730","GO:0009087","GO:0033353"]},{"accession":"XP_045389249.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574","GO:0001178","GO:2000616","GO:0048752","GO:0045038","GO:0098532","GO:0021553","GO:0010048","GO:0009416","GO:0044030","GO:0003226","GO:0036302","GO:0042766","GO:0051225","GO:0000122","GO:0036124","GO:0043044","GO:0030540","GO:0006363","GO:0036123","GO:0060303","GO:2001229","GO:0006369","GO:0006368","GO:0010425","GO:0010426","GO:2000270","GO:0045857","GO:0008015","GO:0007512","GO:1902368","GO:0016973","GO:0060123","GO:0003222","GO:0036091","GO:0016584","GO:0043584","GO:2000104","GO:0033697","GO:1900050","GO:0015074","GO:0071441","GO:0007098","GO:0010880","GO:0071894"]},{"accession":"XP_045405934.1","go_terms":["GO:0006556","GO:0006730","GO:0009087","GO:0033353"]},{"accession":"XP_045407575.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574","GO:0001178","GO:2000616","GO:0048752","GO:0045038","GO:0098532","GO:0021553","GO:0010048","GO:0009416","GO:0044030","GO:0003226","GO:0036302","GO:0042766","GO:0051225","GO:0000122","GO:0036124","GO:0043044","GO:0030540","GO:0006363","GO:0036123","GO:0060303","GO:2001229","GO:0006369","GO:0006368","GO:0010425","GO:0010426","GO:2000270","GO:0045857","GO:0008015","GO:0007512","GO:1902368","GO:0016973","GO:0060123","GO:0003222","GO:0036091","GO:0016584","GO:0043584","GO:2000104","GO:0033697","GO:1900050","GO:0015074","GO:0071441","GO:0007098","GO:0010880","GO:0071894"]}],"graph":[["XP_045407575.1","XP_045402367.1",0.99],["XP_045407575.1","XP_045405934.1",0.974],["XP_045407575.1","XP_045413603.1",0.978],["XP_045407575.1","XP_045413606.1",0.99],["XP_045407575.1","XP_045409990.1",0.987],["XP_045407575.1","XP_045410177.1",0.986],["XP_045407575.1","XP_045424047.1",0.978],["XP_045407575.1","XP_045389249.1",0.989],["XP_045410177.1","XP_045402367.1",0.94],["XP_045410177.1","XP_045405934.1",0.884],["XP_045410177.1","XP_045413603.1",0.676],["XP_045410177.1","XP_045413606.1",0.613],["XP_045410177.1","XP_045409990.1",0.807],["XP_045410177.1","XP_045424047.1",0.848],["XP_045410177.1","XP_045389249.1",0.993],["XP_045424047.1","XP_045402367.1",0.958],["XP_045424047.1","XP_045405934.1",0.966],["XP_045424047.1","XP_045409990.1",0.861],["XP_045424047.1","XP_045413603.1",0.799],["XP_045424047.1","XP_045413606.1",0.711],["XP_045424047.1","XP_045389249.1",0.978],["XP_045389249.1","XP_045402367.1",0.992],["XP_045389249.1","XP_045405934.1",0.976],["XP_045389249.1","XP_045409990.1",0.99],["XP_045389249.1","XP_045413603.1",0.981],["XP_045389249.1","XP_045413606.1",0.991],["XP_045402367.1","XP_045413603.1",0.915],["XP_045402367.1","XP_045413606.1",0.782],["XP_045402367.1","XP_045409990.1",0.935],["XP_045402367.1","XP_045405934.1",0.985],["XP_045413606.1","XP_045405934.1",0.85],["XP_045413606.1","XP_045409990.1",0.732],["XP_045409990.1","XP_045405934.1",0.862],["XP_045409990.1","XP_045413603.1",0.797],["XP_045405934.1","XP_045413603.1",0.885]],"all_go_terms":{"GO:0006099":5,"GO:0043627":5,"GO:0055114":5,"GO:0051591":5,"GO:0006734":5,"GO:0006107":5,"GO:0043065":5,"GO:0007584":5,"GO:0042542":5,"GO:0006097":5,"GO:0019244":5,"GO:0006096":5,"GO:0042493":5,"GO:0048569":5,"GO:0009749":5,"GO:0080093":5,"GO:0006108":5,"GO:0001666":5,"GO:0006556":2,"GO:0009087":2,"GO:0033353":2,"GO:0006730":2,"GO:0036124":2,"GO:0042372":2,"GO:0006635":2,"GO:0003226":2,"GO:0006368":2,"GO:0007098":2,"GO:0008015":2,"GO:0010048":2,"GO:0036091":2,"GO:0060303":2,"GO:1900050":2,"GO:0010426":2,"GO:2001229":2,"GO:0017000":2,"GO:0036302":2,"GO:0006363":2,"GO:0006369":2,"GO:0043044":2,"GO:0030540":2,"GO:0001178":2,"GO:0098532":2,"GO:0000122":2,"GO:0071441":2,"GO:1902368":2,"GO:0007512":2,"GO:0016584":2,"GO:0071894":2,"GO:0045038":2,"GO:0044030":2,"GO:0010425":2,"GO:0003222":2,"GO:2000270":2,"GO:0033697":2,"GO:0043584":2,"GO:0010880":2,"GO:0045857":2,"GO:0009234":2,"GO:2000104":2,"GO:0010124":2,"GO:0009416":2,"GO:2000616":2,"GO:0016973":2,"GO:0015074":2,"GO:0048752":2,"GO:0051225":2,"GO:0060123":2,"GO:0006574":2,"GO:0042766":2,"GO:0021553":2,"GO:0036123":2},"recipe_readded":[]}