{"hash":"2260931371782021733","title":"Iron Homeostasis and Stress Response","description":"Top GO terms point to iron-sulfur cluster assembly and intracellular iron sequestration, indicating a core role in iron handling. Additional terms relate to protein targeting and broad stress-response regulation (ER stress, heat, and oxidative stress-related apoptosis), suggesting a cluster of proteins involved in maintaining iron metabolism under cellular stress, even if several terms are obsolete. Overall, the theme centers on iron homeostasis linked with stress protection.","confidence":"Medium","size":7,"edges":21,"triangles":35,"max_degree":6,"top_function":"DNA replication","members":[{"accession":"XP_045397676.1","go_terms":["GO:0000902","GO:0090084","GO:1903382","GO:1900035","GO:0000742","GO:0006880","GO:0016226","GO:1902037","GO:0070880","GO:0006260","GO:0034620","GO:0031204","GO:1903751","GO:0006616","GO:0070389"]},{"accession":"XP_045397678.1","go_terms":["GO:0000902","GO:0090084","GO:1903382","GO:1900035","GO:0000742","GO:0006880","GO:0016226","GO:1902037","GO:0070880","GO:0006260","GO:0034620","GO:0031204","GO:1903751","GO:0006616","GO:0070389"]},{"accession":"XP_045406870.1","go_terms":["GO:0000902","GO:0090084","GO:1903382","GO:1900035","GO:0000742","GO:0006880","GO:0016226","GO:1902037","GO:0070880","GO:0006260","GO:0034620","GO:0031204","GO:1903751","GO:0006616","GO:0070389"]},{"accession":"XP_045411729.1","go_terms":["GO:0000902","GO:0090084","GO:1903382","GO:1900035","GO:0000742","GO:0006880","GO:0016226","GO:1902037","GO:0070880","GO:0006260","GO:0034620","GO:0031204","GO:1903751","GO:0006616","GO:0070389"]},{"accession":"XP_045419104.1","go_terms":["GO:0000902","GO:0090084","GO:1903382","GO:1900035","GO:0000742","GO:0006880","GO:0016226","GO:1902037","GO:0070880","GO:0006260","GO:0034620","GO:0031204","GO:1903751","GO:0006616","GO:0070389"]},{"accession":"XP_045420398.1","go_terms":["GO:0000902","GO:0090084","GO:1903382","GO:1900035","GO:0000742","GO:0006880","GO:0016226","GO:1902037","GO:0070880","GO:0006260","GO:0034620","GO:0031204","GO:1903751","GO:0006616","GO:0070389"]},{"accession":"XP_045421746.1","go_terms":["GO:0000902","GO:0090084","GO:1903382","GO:1900035","GO:0000742","GO:0006880","GO:0016226","GO:1902037","GO:0070880","GO:0006260","GO:0034620","GO:0031204","GO:1903751","GO:0006616","GO:0070389"]}],"graph":[["XP_045421746.1","XP_045397676.1",0.699],["XP_045421746.1","XP_045397678.1",0.658],["XP_045421746.1","XP_045406870.1",0.725],["XP_045421746.1","XP_045411729.1",0.777],["XP_045421746.1","XP_045419104.1",0.576],["XP_045421746.1","XP_045420398.1",0.873],["XP_045419104.1","XP_045397676.1",0.689],["XP_045419104.1","XP_045397678.1",0.607],["XP_045419104.1","XP_045406870.1",0.742],["XP_045419104.1","XP_045411729.1",0.706],["XP_045419104.1","XP_045420398.1",0.898],["XP_045420398.1","XP_045397676.1",0.826],["XP_045420398.1","XP_045397678.1",0.752],["XP_045420398.1","XP_045406870.1",0.914],["XP_045420398.1","XP_045411729.1",0.887],["XP_045397678.1","XP_045397676.1",0.79],["XP_045397678.1","XP_045406870.1",0.798],["XP_045397678.1","XP_045411729.1",0.91],["XP_045406870.1","XP_045411729.1",0.819],["XP_045406870.1","XP_045397676.1",0.84],["XP_045397676.1","XP_045411729.1",0.83]],"all_go_terms":{"GO:0016226":7,"GO:0070389":7,"GO:0070880":7,"GO:1903382":7,"GO:0006880":7,"GO:0031204":7,"GO:1900035":7,"GO:1902037":7,"GO:0006260":7,"GO:1903751":7,"GO:0000902":7,"GO:0006616":7,"GO:0090084":7,"GO:0000742":7,"GO:0034620":7},"recipe_readded":[]}