{"hash":"1764646785032553653","title":"Ig Diversification & Epigenetic Regulation","description":"The terms point to immunoglobulin gene diversification, including somatic hypermutation and isotype switching to IgA, together with epigenetic processes such as DNA methylation and histone methylation, suggesting a theme of epigenetic control in B cell antibody maturation. A few terms (e.g., DNA restriction-modification) appear as outliers, but the core signal centers on immunoglobulin diversification governed by epigenetic regulation.","confidence":"Medium","size":3,"edges":1,"triangles":0,"max_degree":1,"top_function":null,"members":[{"accession":"XP_045384783.1","go_terms":["GO:0009307","GO:0051571","GO:0051573","GO:0090309","GO:0010216","GO:0090116","GO:0010069","GO:0043046","GO:0043045","GO:0006346","GO:0010425","GO:0010424","GO:0010426","GO:0003289","GO:0043966","GO:0045190","GO:0003290","GO:1903758","GO:0051096","GO:0006349","GO:0000414","GO:0010452","GO:0003149","GO:1903025","GO:0016446","GO:0048298"]},{"accession":"XP_045386015.1","go_terms":["GO:0042006","GO:0030514","GO:0030512","GO:0042347","GO:0010074","GO:0046827","GO:0000173","GO:0080005","GO:0071560","GO:0061191","GO:0035970","GO:0010991","GO:0006470","GO:0000160"]},{"accession":"XP_045385081.1","go_terms":["GO:0032091","GO:0010951","GO:0097211","GO:0007620","GO:2000354","GO:0048747","GO:0060021","GO:0001501","GO:0043392","GO:0019731"]}],"graph":[["XP_045385081.1","XP_045386015.1",0.555]],"all_go_terms":{"GO:0043045":1,"GO:0016446":1,"GO:0009307":1,"GO:0010426":1,"GO:0051573":1,"GO:0003290":1,"GO:0051096":1,"GO:0043046":1,"GO:0048298":1,"GO:0010424":1,"GO:0010425":1,"GO:0003149":1,"GO:0051571":1,"GO:0090116":1,"GO:0090309":1,"GO:0010069":1,"GO:0003289":1,"GO:0006349":1,"GO:0006346":1,"GO:0010216":1,"GO:1903758":1,"GO:0010452":1,"GO:0045190":1,"GO:0043966":1,"GO:1903025":1,"GO:0000414":1,"GO:0042347":1,"GO:0071560":1,"GO:0006470":1,"GO:0030514":1,"GO:0061191":1,"GO:0000160":1,"GO:0046827":1,"GO:0030512":1,"GO:0035970":1,"GO:0010991":1,"GO:0042006":1,"GO:0000173":1,"GO:0010074":1,"GO:0080005":1,"GO:0001501":1,"GO:2000354":1,"GO:0010951":1,"GO:0032091":1,"GO:0007620":1,"GO:0043392":1,"GO:0048747":1,"GO:0019731":1,"GO:0060021":1,"GO:0097211":1},"recipe_readded":["XP_045396045.1"]}