{"hash":"1510613154098534830","title":"Mitochondrial tRNA aminoacylation and translation","description":"This cluster is characterized by GO terms centered on mitochondrial tRNA charging (serine, proline, glycyl, histidine, alanine) and the broader process of translation, along with mitochondrial DNA metabolic activity and regulation of translational fidelity. The convergence of multiple mitochondrial aminoacyl-tRNA synthetase activities with translation-related terms strongly suggests proteins involved in mitochondrial protein synthesis and tRNA charging machinery, despite a digression to an obsolete selenocysteinyl-tRNA biosynthetic term. ","confidence":"High","size":11,"edges":18,"triangles":3,"max_degree":7,"top_function":"cytoplasmic translation","members":[{"accession":"XP_045400900.1","go_terms":["GO:0032042","GO:0070150","GO:0006450","GO:0006433","GO:0006427","GO:0070159","GO:0015966","GO:0001701","GO:0022904","GO:0070584","GO:0006412","GO:0071897","GO:0016260","GO:0070158","GO:0097056","GO:0006435","GO:0070143","GO:0015970","GO:1903833","GO:0002181"]},{"accession":"XP_045416972.1","go_terms":["GO:0032042","GO:0070150","GO:0006450","GO:0006433","GO:0006427","GO:0070159","GO:0015966","GO:0001701","GO:0022904","GO:0070584","GO:0006412","GO:0071897","GO:0016260","GO:0070158","GO:0097056","GO:0006435","GO:0070143","GO:0015970","GO:1903833","GO:0002181"]},{"accession":"XP_045421759.1","go_terms":["GO:0032042","GO:0070150","GO:0006450","GO:0006433","GO:0006427","GO:0070159","GO:0015966","GO:0001701","GO:0022904","GO:0070584","GO:0006412","GO:0071897","GO:0016260","GO:0070158","GO:0097056","GO:0006435","GO:0070143","GO:0015970","GO:1903833","GO:0002181"]},{"accession":"XP_045397389.1","go_terms":[]},{"accession":"XP_045404846.1","go_terms":[]},{"accession":"XP_045407118.1","go_terms":["GO:0016049","GO:0007035","GO:0015991","GO:0000032"]},{"accession":"XP_045421025.1","go_terms":["GO:0016049","GO:0007035","GO:0015991","GO:0000032"]},{"accession":"XP_045425639.1","go_terms":[]},{"accession":"XP_045384821.1","go_terms":["GO:0017196"]},{"accession":"XP_045389561.1","go_terms":["GO:2000253","GO:0018095","GO:0060296"]},{"accession":"XP_045393684.1","go_terms":["GO:0008625","GO:0032088"]}],"graph":[["XP_045397389.1","XP_045416972.1",0.859],["XP_045397389.1","XP_045421759.1",0.963],["XP_045397389.1","XP_045400900.1",0.963],["XP_045389561.1","XP_045400900.1",0.963],["XP_045389561.1","XP_045416972.1",0.963],["XP_045400900.1","XP_045404846.1",0.856],["XP_045400900.1","XP_045407118.1",0.915],["XP_045400900.1","XP_045421759.1",0.674],["XP_045400900.1","XP_045425639.1",0.924],["XP_045400900.1","XP_045384821.1",0.515],["XP_045393684.1","XP_045404846.1",0.747],["XP_045421025.1","XP_045416972.1",0.857],["XP_045384821.1","XP_045416972.1",0.713],["XP_045421759.1","XP_045404846.1",0.784],["XP_045421759.1","XP_045407118.1",0.504],["XP_045425639.1","XP_045416972.1",0.857],["XP_045407118.1","XP_045416972.1",0.962],["XP_045404846.1","XP_045416972.1",0.774]],"all_go_terms":{"GO:0071897":3,"GO:0070158":3,"GO:0097056":3,"GO:0006433":3,"GO:0006412":3,"GO:0006450":3,"GO:0032042":3,"GO:0070150":3,"GO:0006427":3,"GO:0070143":3,"GO:0006435":3,"GO:0070159":3,"GO:0015966":3,"GO:0070584":3,"GO:0002181":3,"GO:0022904":3,"GO:1903833":3,"GO:0016260":3,"GO:0015970":3,"GO:0001701":3,"GO:0015991":2,"GO:0016049":2,"GO:0007035":2,"GO:0000032":2,"GO:0017196":1,"GO:0060296":1,"GO:0018095":1,"GO:2000253":1,"GO:0032088":1,"GO:0008625":1},"recipe_readded":[]}