{"hash":"1107848715164522882","title":"Ribosome biogenesis and translation regulation","description":"The top GO terms cluster around ribosome production and function: ribosomal small subunit assembly, maturation of SSU rRNA, and translation. Additional terms such as mRNA capping and methylation hint at broader RNA processing linked to protein synthesis; deubiquitination and apoptotic regulation may reflect quality control connected to translation. Overall, the core theme is ribosome biogenesis coupled with translation control.","confidence":"Medium","size":19,"edges":16,"triangles":5,"max_degree":6,"top_function":null,"members":[{"accession":"XP_045403703.1","go_terms":["GO:0003283","GO:0010378","GO:0071947","GO:1990168","GO:0000381","GO:0003203","GO:0000122","GO:0043066","GO:1904404","GO:0046832","GO:0071600","GO:0008380","GO:0070536","GO:0006977","GO:0033132","GO:0035523","GO:1900871","GO:0045023","GO:0090526","GO:0036292","GO:0071301","GO:0016567","GO:0003181","GO:0071157"]},{"accession":"XP_045403743.1","go_terms":["GO:0042981","GO:0043392","GO:0016579"]},{"accession":"XP_045403745.1","go_terms":["GO:0042981","GO:0043392","GO:0016579"]},{"accession":"XP_045414593.1","go_terms":[]},{"accession":"XP_045401068.1","go_terms":["GO:0007638","GO:0045071","GO:0007283","GO:0006955","GO:0007286"]},{"accession":"XP_045417544.1","go_terms":["GO:0036031","GO:0006370","GO:0032259"]},{"accession":"XP_045399430.1","go_terms":["GO:0032781","GO:0016973","GO:0051096"]},{"accession":"XP_045382759.1","go_terms":["GO:0000028","GO:0000462","GO:0006412"]},{"accession":"XP_045383648.1","go_terms":[]},{"accession":"XP_045383975.1","go_terms":["GO:0071549","GO:0006281","GO:0006412"]},{"accession":"XP_045396665.1","go_terms":["GO:0000028","GO:0000462","GO:0006412"]},{"accession":"XP_045399871.1","go_terms":["GO:0042273","GO:0000055","GO:0006412"]},{"accession":"XP_045393409.1","go_terms":["GO:0042254","GO:0006412"]},{"accession":"XP_045387973.1","go_terms":["GO:0006356","GO:0008033","GO:0031167","GO:0048254","GO:1990258","GO:0000494"]},{"accession":"XP_045414392.1","go_terms":["GO:0031444","GO:0045932","GO:0001980","GO:0055010","GO:0032780","GO:0032781","GO:0043057","GO:0030049","GO:0014883","GO:0006942","GO:0045214","GO:0060048","GO:0032972","GO:0006940"]},{"accession":"XP_045417545.1","go_terms":["GO:0036031","GO:0006370","GO:0032259"]},{"accession":"XP_045419625.1","go_terms":[]},{"accession":"XP_045403217.1","go_terms":["GO:0000055","GO:0032298","GO:0000398","GO:1903026","GO:1990126","GO:0006886","GO:0008333","GO:1904263","GO:0035542","GO:0099022","GO:0042144","GO:0032889","GO:1902774","GO:0034058","GO:0060707","GO:0003323","GO:0060806","GO:0035270","GO:0060972","GO:0060536","GO:0003198","GO:0032436","GO:0048752","GO:0033081","GO:0048066","GO:0021766","GO:0090243","GO:0043507","GO:0000209","GO:0007417","GO:0090103","GO:0045602","GO:0010464","GO:0021957","GO:0061373","GO:0002250","GO:0097324","GO:1903056","GO:0060030","GO:0048668","GO:0021540","GO:0032480","GO:0010792","GO:0001755","GO:0001756","GO:0051216","GO:0039536","GO:0050772","GO:0051150","GO:0021846","GO:1902748","GO:0048596","GO:0045636","GO:0007498","GO:0060021","GO:0031069","GO:0010957"]},{"accession":"XP_045391870.1","go_terms":["GO:0000910","GO:0007252","GO:0042052","GO:0035773","GO:0070164","GO:0045055","GO:0003407","GO:0032456","GO:0016360","GO:1903452"]}],"graph":[["XP_045387973.1","XP_045403217.1",0.691],["XP_045387973.1","XP_045399430.1",0.648],["XP_045393409.1","XP_045417544.1",0.556],["XP_045393409.1","XP_045417545.1",0.543],["XP_045393409.1","XP_045382759.1",0.646],["XP_045393409.1","XP_045383975.1",0.92],["XP_045393409.1","XP_045396665.1",0.558],["XP_045393409.1","XP_045399871.1",0.791],["XP_045391870.1","XP_045382759.1",0.528],["XP_045399430.1","XP_045403217.1",0.57],["XP_045396665.1","XP_045383975.1",0.768],["XP_045396665.1","XP_045403217.1",0.532],["XP_045396665.1","XP_045399871.1",0.882],["XP_045382759.1","XP_045403217.1",0.55],["XP_045383975.1","XP_045399871.1",0.884],["XP_045403217.1","XP_045417545.1",0.578]],"all_go_terms":{"GO:0070536":1,"GO:0090526":1,"GO:0003203":1,"GO:0033132":1,"GO:1904404":1,"GO:0071600":1,"GO:0036292":1,"GO:0000122":1,"GO:0045023":1,"GO:0008380":1,"GO:0010378":1,"GO:0003181":1,"GO:0000381":1,"GO:0046832":1,"GO:1990168":1,"GO:0006977":1,"GO:0071301":1,"GO:0071157":1,"GO:0016567":1,"GO:0035523":1,"GO:1900871":1,"GO:0071947":1,"GO:0003283":1,"GO:0043066":1,"GO:0042981":2,"GO:0016579":2,"GO:0043392":2,"GO:0007283":1,"GO:0006955":1,"GO:0007638":1,"GO:0007286":1,"GO:0045071":1,"GO:0006370":2,"GO:0032259":2,"GO:0036031":2,"GO:0032781":2,"GO:0051096":1,"GO:0016973":1,"GO:0006412":5,"GO:0000028":2,"GO:0000462":2,"GO:0071549":1,"GO:0006281":1,"GO:0000055":2,"GO:0042273":1,"GO:0042254":1,"GO:0031167":1,"GO:0008033":1,"GO:0048254":1,"GO:1990258":1,"GO:0006356":1,"GO:0000494":1,"GO:0014883":1,"GO:0055010":1,"GO:0045214":1,"GO:0006942":1,"GO:0006940":1,"GO:0030049":1,"GO:0032780":1,"GO:0060048":1,"GO:0031444":1,"GO:0001980":1,"GO:0043057":1,"GO:0032972":1,"GO:0045932":1,"GO:0008333":1,"GO:0060806":1,"GO:0099022":1,"GO:1903056":1,"GO:0048596":1,"GO:0060021":1,"GO:0097324":1,"GO:0000209":1,"GO:0000398":1,"GO:0048668":1,"GO:0002250":1,"GO:0090103":1,"GO:0010792":1,"GO:0042144":1,"GO:0033081":1,"GO:0060536":1,"GO:0039536":1,"GO:1903026":1,"GO:0060030":1,"GO:0032436":1,"GO:0001755":1,"GO:1902774":1,"GO:0007417":1,"GO:0051150":1,"GO:0032298":1,"GO:0035270":1,"GO:0060972":1,"GO:0032889":1,"GO:0021957":1,"GO:0021766":1,"GO:0007498":1,"GO:0010957":1,"GO:0010464":1,"GO:0045602":1,"GO:0061373":1,"GO:0001756":1,"GO:0048066":1,"GO:0031069":1,"GO:0006886":1,"GO:0045636":1,"GO:1990126":1,"GO:0032480":1,"GO:0003323":1,"GO:1902748":1,"GO:1904263":1,"GO:0060707":1,"GO:0021846":1,"GO:0048752":1,"GO:0021540":1,"GO:0003198":1,"GO:0035542":1,"GO:0090243":1,"GO:0034058":1,"GO:0051216":1,"GO:0043507":1,"GO:0050772":1,"GO:0035773":1,"GO:1903452":1,"GO:0032456":1,"GO:0000910":1,"GO:0007252":1,"GO:0003407":1,"GO:0045055":1,"GO:0042052":1,"GO:0016360":1,"GO:0070164":1},"recipe_readded":["XP_045409269.1","XP_045422077.1","XP_045398896.1","XP_045392389.1","XP_045385064.1","XP_045406398.1","XP_045399027.1","XP_045389562.1","XP_045403756.1","XP_045415722.1","XP_045385234.1","XP_045424628.1","XP_045414540.1","XP_045396355.1","XP_045409920.1","XP_045406310.1","XP_045409089.1","XP_045385948.1","XP_045409922.1","XP_045390853.1"]}