{"hash":"1893219824822019912","title":"Membrane protein targeting and translocation","description":"This cluster is dominated by GO terms related to membrane targeting and translocation, especially SRP-dependent cotranslational targeting to membranes and post-translational targeting to membranes, suggesting a set of proteins involved in directing nascent proteins to membranes and into appropriate compartments. Other terms (iron-sulfur cluster assembly, karyogamy, stress-regulated apoptosis) are present but less central, likely reflecting ancillary roles or annotation overlap. ","confidence":"Medium","size":15,"edges":93,"triangles":321,"max_degree":14,"top_function":"DNA replication","members":[{"accession":"XP_055337884.1","go_terms":["GO:1990535","GO:0090307","GO:0032886","GO:0000022","GO:0007100","GO:0030951","GO:0031534","GO:0031535","GO:0009904","GO:0007080","GO:0033624","GO:0021693","GO:0072092","GO:0060404","GO:0030473","GO:0010938","GO:0051296","GO:0001560","GO:0032487","GO:0045218","GO:0000073","GO:0000911","GO:0000915","GO:0072383","GO:0051255","GO:0036334","GO:0070462","GO:0098971","GO:0048364","GO:0021685","GO:0099607","GO:0035617","GO:1990942","GO:0000743","GO:0000742"]},{"accession":"XP_055337994.1","go_terms":["GO:0034085","GO:0048568","GO:0000717","GO:0032289","GO:0072719","GO:1904506","GO:1902990","GO:0010705","GO:0043249","GO:0035264","GO:0009408","GO:0007064","GO:0043247","GO:0001666","GO:1904976","GO:0010569","GO:0001701","GO:1990918","GO:0008283","GO:0021510","GO:0033683","GO:0030282","GO:0048820","GO:0045951","GO:0006366","GO:0006260","GO:0043588","GO:0010525","GO:0090657","GO:0009411","GO:1904535","GO:0072711","GO:0006289","GO:0007284","GO:1990700","GO:0060218","GO:0035563","GO:0045005","GO:0009791","GO:0007568","GO:0040016","GO:0070816","GO:0036297","GO:0000732","GO:0030198","GO:1901838","GO:0051026","GO:0043388","GO:1904430","GO:0006295","GO:0006294","GO:0006293","GO:0009650","GO:0035315","GO:0007348","GO:0006363","GO:0006361","GO:0006362","GO:0006283","GO:0000184","GO:0001113","GO:0001111","GO:0009432","GO:0006306","GO:0006265","GO:0006367","GO:0006268","GO:0006269","GO:0060543","GO:0009307","GO:0039530","GO:0045876","GO:0072520","GO:0032079","GO:0044806"]},{"accession":"XP_055332427.1","go_terms":[]},{"accession":"XP_055337618.1","go_terms":["GO:0045907","GO:0034605","GO:0007612","GO:0007613","GO:0002149","GO:0010042","GO:0045986","GO:0045987","GO:0045786","GO:0009750","GO:0001580","GO:0006979","GO:0098869","GO:0030216","GO:0090362","GO:0001516","GO:0051591","GO:0090271","GO:0008365","GO:0007568","GO:0055114","GO:0032227","GO:0070542","GO:0034374","GO:0006590","GO:0042744","GO:0042742","GO:0032496","GO:0030282","GO:0071456","GO:0019233","GO:0048477","GO:0006954","GO:0042633","GO:0090050","GO:0043154","GO:0032714","GO:0001878","GO:0051968","GO:0002215","GO:1902609","GO:0035633","GO:1902219","GO:0045429","GO:0034644","GO:0033280","GO:0071471","GO:0031394","GO:0071260","GO:0008285","GO:0010226","GO:0050873","GO:0090336","GO:0010575","GO:0031622","GO:0007566","GO:0042493","GO:0051384","GO:0033138","GO:1990268","GO:0008217","GO:0001525","GO:0032355","GO:0030728","GO:0050665","GO:0043065","GO:0071318","GO:0019371","GO:0048661","GO:0034612","GO:0071498","GO:0042346","GO:0048855","GO:0051926","GO:0002679","GO:0046697","GO:0031915","GO:0071636"]},{"accession":"XP_055339835.1","go_terms":["GO:0006909","GO:0030240","GO:0010628","GO:0021762","GO:0034314","GO:0051654","GO:0002121","GO:0042766","GO:0043503","GO:0071963","GO:0009825","GO:0006348","GO:0000147","GO:0000001","GO:0043486","GO:0000281","GO:0016344","GO:0030476","GO:1904623","GO:0048741","GO:0032508","GO:0051017","GO:0045214","GO:0051666","GO:0030041","GO:0001895","GO:0030100","GO:0090131","GO:0051592","GO:0000011","GO:0000916","GO:0001300","GO:0043982","GO:0043983","GO:0043981","GO:0070527","GO:1903475","GO:0098974"]},{"accession":"XP_055340953.1","go_terms":["GO:0090084","GO:1903382","GO:1900035","GO:0000742","GO:0006880","GO:0016226","GO:1902037","GO:0070880","GO:0006260","GO:0034620","GO:0031204","GO:1903751","GO:0006616","GO:0070389"]},{"accession":"XP_055343602.1","go_terms":["GO:2001200","GO:0043380","GO:1900477","GO:0072156","GO:0042748","GO:0042092","GO:0009638","GO:0007519","GO:0045496","GO:2000176","GO:0048294","GO:0042787","GO:0031397","GO:2000312","GO:0050853","GO:0032764","GO:0048741","GO:0002467","GO:1990390","GO:0009958","GO:0070294","GO:1904431","GO:0045497"]},{"accession":"XP_055343969.1","go_terms":["GO:0006471","GO:0006953","GO:0030212","GO:0002291","GO:0003429","GO:0070208","GO:0034113","GO:1905050","GO:0045123","GO:0007229","GO:0007596","GO:0006929","GO:0007161","GO:0031104","GO:0006956","GO:0035987","GO:1901202","GO:0015995","GO:0048455","GO:0006511","GO:0043248","GO:0050908"]},{"accession":"XP_055344450.1","go_terms":[]},{"accession":"XP_055345990.1","go_terms":["GO:0006310","GO:0071932","GO:0000002","GO:0097046","GO:0032508","GO:0032211","GO:0044806","GO:1902983","GO:0051974","GO:0043504","GO:1903469","GO:0000723","GO:0039520","GO:0019082","GO:0039694","GO:0006351","GO:0006396","GO:0090305"]},{"accession":"XP_055347793.1","go_terms":["GO:0090084","GO:1903382","GO:1900035","GO:0000742","GO:0006880","GO:0016226","GO:1902037","GO:0070880","GO:0006260","GO:0034620","GO:0031204","GO:1903751","GO:0006616","GO:0070389"]},{"accession":"XP_055348923.1","go_terms":["GO:0090084","GO:1903382","GO:1900035","GO:0000742","GO:0006880","GO:0016226","GO:1902037","GO:0070880","GO:0006260","GO:0034620","GO:0031204","GO:1903751","GO:0006616","GO:0070389"]},{"accession":"XP_055348937.1","go_terms":["GO:0090084","GO:1903382","GO:1900035","GO:0000742","GO:0006880","GO:0016226","GO:1902037","GO:0070880","GO:0006260","GO:0034620","GO:0031204","GO:1903751","GO:0006616","GO:0070389"]},{"accession":"XP_055355746.1","go_terms":[]},{"accession":"XP_055355986.1","go_terms":["GO:0010584","GO:0006487","GO:0046706","GO:0046712","GO:0071405","GO:0046032","GO:0009901","GO:0006256"]}],"graph":[["XP_055337994.1","XP_055332427.1",0.982],["XP_055337994.1","XP_055337618.1",0.932],["XP_055337994.1","XP_055339835.1",0.57],["XP_055337994.1","XP_055340953.1",0.701],["XP_055337994.1","XP_055343602.1",0.756],["XP_055337994.1","XP_055343969.1",0.951],["XP_055337994.1","XP_055344450.1",0.791],["XP_055337994.1","XP_055345990.1",0.691],["XP_055337994.1","XP_055347793.1",0.911],["XP_055337994.1","XP_055348923.1",0.885],["XP_055337994.1","XP_055355746.1",0.991],["XP_055337994.1","XP_055355986.1",0.837],["XP_055344450.1","XP_055337618.1",0.843],["XP_055344450.1","XP_055337884.1",0.947],["XP_055344450.1","XP_055339835.1",0.656],["XP_055344450.1","XP_055340953.1",0.938],["XP_055344450.1","XP_055343602.1",0.947],["XP_055344450.1","XP_055343969.1",0.867],["XP_055344450.1","XP_055345990.1",0.963],["XP_055344450.1","XP_055347793.1",0.93],["XP_055344450.1","XP_055355746.1",0.96],["XP_055344450.1","XP_055355986.1",0.73],["XP_055344450.1","XP_055348923.1",0.609],["XP_055344450.1","XP_055348937.1",0.861],["XP_055343969.1","XP_055337884.1",0.927],["XP_055343969.1","XP_055339835.1",0.82],["XP_055343969.1","XP_055340953.1",0.933],["XP_055343969.1","XP_055347793.1",0.935],["XP_055343969.1","XP_055345990.1",0.945],["XP_055343969.1","XP_055348923.1",0.776],["XP_055343969.1","XP_055348937.1",0.905],["XP_055343969.1","XP_055355746.1",0.919],["XP_055343969.1","XP_055355986.1",0.82],["XP_055345990.1","XP_055332427.1",0.913],["XP_055345990.1","XP_055337618.1",0.78],["XP_055345990.1","XP_055337884.1",0.631],["XP_055345990.1","XP_055339835.1",0.958],["XP_055345990.1","XP_055340953.1",0.98],["XP_055345990.1","XP_055343602.1",0.508],["XP_055345990.1","XP_055347793.1",0.976],["XP_055345990.1","XP_055348923.1",0.937],["XP_055345990.1","XP_055348937.1",0.841],["XP_055345990.1","XP_055355746.1",0.975],["XP_055345990.1","XP_055355986.1",0.844],["XP_055347793.1","XP_055332427.1",0.993],["XP_055347793.1","XP_055337618.1",0.871],["XP_055347793.1","XP_055337884.1",0.845],["XP_055347793.1","XP_055339835.1",0.956],["XP_055347793.1","XP_055340953.1",0.972],["XP_055347793.1","XP_055343602.1",0.93],["XP_055347793.1","XP_055348923.1",0.895],["XP_055347793.1","XP_055348937.1",0.872],["XP_055347793.1","XP_055355746.1",0.935],["XP_055347793.1","XP_055355986.1",0.916],["XP_055337618.1","XP_055337884.1",0.945],["XP_055337618.1","XP_055339835.1",0.829],["XP_055337618.1","XP_055340953.1",0.825],["XP_055337618.1","XP_055348923.1",0.744],["XP_055337618.1","XP_055348937.1",0.881],["XP_055337618.1","XP_055355986.1",0.862],["XP_055332427.1","XP_055337884.1",0.796],["XP_055332427.1","XP_055339835.1",0.987],["XP_055332427.1","XP_055340953.1",0.988],["XP_055332427.1","XP_055348923.1",0.974],["XP_055332427.1","XP_055348937.1",0.965],["XP_055332427.1","XP_055355986.1",0.975],["XP_055337884.1","XP_055339835.1",0.804],["XP_055337884.1","XP_055340953.1",0.747],["XP_055337884.1","XP_055343602.1",0.79],["XP_055337884.1","XP_055348923.1",0.607],["XP_055337884.1","XP_055348937.1",0.845],["XP_055337884.1","XP_055355746.1",0.954],["XP_055337884.1","XP_055355986.1",0.557],["XP_055348937.1","XP_055339835.1",0.894],["XP_055348937.1","XP_055340953.1",0.612],["XP_055348937.1","XP_055343602.1",0.935],["XP_055348937.1","XP_055348923.1",0.704],["XP_055348937.1","XP_055355746.1",0.972],["XP_055348937.1","XP_055355986.1",0.87],["XP_055355986.1","XP_055339835.1",0.916],["XP_055355986.1","XP_055340953.1",0.622],["XP_055355986.1","XP_055343602.1",0.936],["XP_055355986.1","XP_055348923.1",0.849],["XP_055355986.1","XP_055355746.1",0.949],["XP_055343602.1","XP_055339835.1",0.903],["XP_055343602.1","XP_055340953.1",0.843],["XP_055343602.1","XP_055348923.1",0.876],["XP_055339835.1","XP_055340953.1",0.712],["XP_055339835.1","XP_055355746.1",0.982],["XP_055339835.1","XP_055348923.1",0.886],["XP_055355746.1","XP_055340953.1",0.981],["XP_055355746.1","XP_055348923.1",0.944],["XP_055340953.1","XP_055348923.1",0.791]],"all_go_terms":{"GO:0007080":1,"GO:0021685":1,"GO:0000915":1,"GO:1990535":1,"GO:0060404":1,"GO:0035617":1,"GO:0051296":1,"GO:0099607":1,"GO:0036334":1,"GO:0009904":1,"GO:0045218":1,"GO:0072383":1,"GO:0032886":1,"GO:0010938":1,"GO:0090307":1,"GO:0033624":1,"GO:0021693":1,"GO:0001560":1,"GO:0098971":1,"GO:0007100":1,"GO:0048364":1,"GO:0070462":1,"GO:0000743":1,"GO:0000022":1,"GO:0031535":1,"GO:0030473":1,"GO:0000742":5,"GO:1990942":1,"GO:0030951":1,"GO:0000911":1,"GO:0031534":1,"GO:0032487":1,"GO:0051255":1,"GO:0072092":1,"GO:0000073":1,"GO:0060543":1,"GO:0072520":1,"GO:0000717":1,"GO:1902990":1,"GO:0007064":1,"GO:0006363":1,"GO:0030198":1,"GO:0043388":1,"GO:0006265":1,"GO:0045876":1,"GO:0009791":1,"GO:0006295":1,"GO:0000732":1,"GO:1904976":1,"GO:0006366":1,"GO:0021510":1,"GO:0045951":1,"GO:0060218":1,"GO:0009408":1,"GO:0090657":1,"GO:0008283":1,"GO:0032289":1,"GO:0009411":1,"GO:0009432":1,"GO:0001111":1,"GO:0039530":1,"GO:0032079":1,"GO:1904430":1,"GO:0040016":1,"GO:0035315":1,"GO:0010705":1,"GO:0006268":1,"GO:0006293":1,"GO:1904535":1,"GO:0035264":1,"GO:0006289":1,"GO:0051026":1,"GO:0007348":1,"GO:0030282":2,"GO:0000184":1,"GO:1904506":1,"GO:0043247":1,"GO:0048568":1,"GO:0070816":1,"GO:0001113":1,"GO:0006283":1,"GO:0010525":1,"GO:0045005":1,"GO:1990700":1,"GO:0006361":1,"GO:0001701":1,"GO:0044806":2,"GO:0006269":1,"GO:0048820":1,"GO:0036297":1,"GO:0034085":1,"GO:0007284":1,"GO:0001666":1,"GO:0006362":1,"GO:0043588":1,"GO:0007568":2,"GO:0009650":1,"GO:0006306":1,"GO:0033683":1,"GO:1990918":1,"GO:0072719":1,"GO:0043249":1,"GO:0035563":1,"GO:0072711":1,"GO:0006367":1,"GO:0006294":1,"GO:0010569":1,"GO:0006260":5,"GO:1901838":1,"GO:0009307":1,"GO:1902609":1,"GO:0033138":1,"GO:0046697":1,"GO:0007566":1,"GO:0051968":1,"GO:0002679":1,"GO:0032227":1,"GO:0042742":1,"GO:0031915":1,"GO:0006979":1,"GO:0006954":1,"GO:0032496":1,"GO:0090336":1,"GO:0002149":1,"GO:0043154":1,"GO:0034612":1,"GO:0031622":1,"GO:0050665":1,"GO:0010575":1,"GO:0043065":1,"GO:0045987":1,"GO:0008285":1,"GO:0032714":1,"GO:0071471":1,"GO:0002215":1,"GO:0034374":1,"GO:0050873":1,"GO:0045986":1,"GO:0090362":1,"GO:0019371":1,"GO:0007613":1,"GO:0048477":1,"GO:0035633":1,"GO:1902219":1,"GO:0007612":1,"GO:0010042":1,"GO:0048661":1,"GO:1990268":1,"GO:0051591":1,"GO:0051384":1,"GO:0001525":1,"GO:0042493":1,"GO:0019233":1,"GO:0048855":1,"GO:0071498":1,"GO:0034605":1,"GO:0010226":1,"GO:0055114":1,"GO:0070542":1,"GO:0008217":1,"GO:0031394":1,"GO:0001516":1,"GO:0051926":1,"GO:0071318":1,"GO:0071260":1,"GO:0030728":1,"GO:0034644":1,"GO:0045429":1,"GO:0090271":1,"GO:0042633":1,"GO:0032355":1,"GO:0001580":1,"GO:0030216":1,"GO:0090050":1,"GO:0006590":1,"GO:0098869":1,"GO:0071456":1,"GO:0042744":1,"GO:0001878":1,"GO:0033280":1,"GO:0071636":1,"GO:0045786":1,"GO:0009750":1,"GO:0042346":1,"GO:0045907":1,"GO:0008365":1,"GO:0000011":1,"GO:0009825":1,"GO:0000147":1,"GO:0048741":2,"GO:0030240":1,"GO:0030100":1,"GO:0051592":1,"GO:0043486":1,"GO:0043983":1,"GO:0090131":1,"GO:0045214":1,"GO:0000281":1,"GO:0043503":1,"GO:0001300":1,"GO:0098974":1,"GO:0016344":1,"GO:0051017":1,"GO:0010628":1,"GO:0043981":1,"GO:0030041":1,"GO:0021762":1,"GO:0051666":1,"GO:0000916":1,"GO:0042766":1,"GO:0043982":1,"GO:0006909":1,"GO:0000001":1,"GO:0032508":2,"GO:0071963":1,"GO:0030476":1,"GO:0051654":1,"GO:0034314":1,"GO:0006348":1,"GO:1903475":1,"GO:0001895":1,"GO:1904623":1,"GO:0002121":1,"GO:0070527":1,"GO:1902037":4,"GO:0006880":4,"GO:1903751":4,"GO:1903382":4,"GO:0031204":4,"GO:1900035":4,"GO:0006616":4,"GO:0016226":4,"GO:0090084":4,"GO:0070880":4,"GO:0034620":4,"GO:0070389":4,"GO:0031397":1,"GO:2000312":1,"GO:0070294":1,"GO:0045496":1,"GO:0042787":1,"GO:1990390":1,"GO:0007519":1,"GO:0045497":1,"GO:0032764":1,"GO:0009638":1,"GO:2000176":1,"GO:0050853":1,"GO:0072156":1,"GO:0048294":1,"GO:0009958":1,"GO:0043380":1,"GO:0042092":1,"GO:0002467":1,"GO:0042748":1,"GO:1904431":1,"GO:1900477":1,"GO:2001200":1,"GO:0070208":1,"GO:0034113":1,"GO:0045123":1,"GO:0007596":1,"GO:0007229":1,"GO:0048455":1,"GO:0050908":1,"GO:0031104":1,"GO:0006471":1,"GO:0043248":1,"GO:0006511":1,"GO:0002291":1,"GO:0006956":1,"GO:1901202":1,"GO:0007161":1,"GO:0035987":1,"GO:0030212":1,"GO:1905050":1,"GO:0006929":1,"GO:0003429":1,"GO:0006953":1,"GO:0015995":1,"GO:0097046":1,"GO:1902983":1,"GO:0071932":1,"GO:0051974":1,"GO:1903469":1,"GO:0039520":1,"GO:0039694":1,"GO:0006351":1,"GO:0090305":1,"GO:0032211":1,"GO:0019082":1,"GO:0006396":1,"GO:0043504":1,"GO:0000002":1,"GO:0006310":1,"GO:0000723":1,"GO:0046706":1,"GO:0010584":1,"GO:0006256":1,"GO:0046712":1,"GO:0009901":1,"GO:0006487":1,"GO:0071405":1,"GO:0046032":1},"recipe_readded":[]}