{"hash":"1338364008727590129","title":"Negative Regulation of Signaling Pathways","description":"These proteins show GO annotations focused on negative regulation across multiple signaling pathways (e.g., Wnt, PI3K/AKT, activin) and also relate to developmental processes (CNS development, heart formation, angiogenesis). The common thread is dampening signaling during development and tissue formation, suggesting a role as general negative regulators of signaling. However, the small cluster size and cross-context annotations warrant a moderate level of confidence.","confidence":"Medium","size":3,"edges":2,"triangles":0,"max_degree":2,"top_function":null,"members":[{"accession":"XP_055331212.1","go_terms":[]},{"accession":"XP_055337382.1","go_terms":["GO:1905456","GO:0032926","GO:1905453","GO:0048147","GO:0035414","GO:0051898","GO:0007417","GO:0060914","GO:0045950","GO:0035914","GO:0007084","GO:0060250","GO:0002044","GO:0048132","GO:0030514","GO:0035307","GO:0070197","GO:0046827"]},{"accession":"XP_055338555.1","go_terms":[]}],"graph":[["XP_055337382.1","XP_055331212.1",0.749],["XP_055337382.1","XP_055338555.1",0.566]],"all_go_terms":{"GO:0035414":1,"GO:0070197":1,"GO:0045950":1,"GO:0035307":1,"GO:0007417":1,"GO:0051898":1,"GO:0048147":1,"GO:0032926":1,"GO:0002044":1,"GO:0060914":1,"GO:0048132":1,"GO:0030514":1,"GO:0046827":1,"GO:1905453":1,"GO:0035914":1,"GO:0060250":1,"GO:1905456":1,"GO:0007084":1},"recipe_readded":[]}