{"hash":"2252258587700009396","title":"DNA Damage Response and Translation Regulation","description":"The cluster shows enrichment for DNA damage response terms (UV and gamma radiation exposure, p53-mediated apoptotic signaling) together with translation and transcription elongation terms and ribosome biogenesis, suggesting a theme where DNA damage signaling modulates transcriptional elongation and protein synthesis during stress.","confidence":"Medium","size":12,"edges":35,"triangles":45,"max_degree":11,"top_function":null,"members":[{"accession":"XP_026693949.2","go_terms":["GO:1902164","GO:1902167","GO:0032784","GO:0006977","GO:1904803","GO:0042273","GO:0031564","GO:0071480","GO:0006354","GO:0006353","GO:0045727","GO:0006412"]},{"accession":"XP_002120861.4","go_terms":[]},{"accession":"XP_078484497.1","go_terms":["GO:0006784"]},{"accession":"XP_078485909.1","go_terms":["GO:0034599","GO:0006515","GO:0007049","GO:0051301","GO:0016558"]},{"accession":"XP_078493786.1","go_terms":["GO:0006796"]},{"accession":"XP_009857913.2","go_terms":["GO:0045849","GO:0060711","GO:0060712","GO:0006964","GO:0046673","GO:1990001","GO:0090307","GO:1902443","GO:0051311","GO:1902523","GO:0000209","GO:0031536","GO:0050727","GO:0045035","GO:0048800","GO:1902527","GO:0032465","GO:0070266","GO:0061469","GO:0000278","GO:0006915","GO:0034121","GO:0070247","GO:0007058","GO:0007059","GO:1902530","GO:0061178","GO:0001890","GO:0031503","GO:1902524","GO:2001271","GO:0043523","GO:0006351","GO:0090263","GO:0043123"]},{"accession":"XP_009857990.2","go_terms":["GO:0008033","GO:0070156","GO:0006412","GO:0071915","GO:0070154","GO:0070145","GO:0070146","GO:0072581","GO:0002101","GO:0070200","GO:0006422","GO:0006430","GO:0006281","GO:0016233","GO:0006260","GO:0006310","GO:0010833","GO:0007093"]},{"accession":"XP_026695098.2","go_terms":["GO:0070126","GO:0070125","GO:0006412"]},{"accession":"XP_078489201.1","go_terms":["GO:0030007","GO:0070131","GO:0051204","GO:0042407"]},{"accession":"XP_078494786.1","go_terms":["GO:0017196"]},{"accession":"XP_002122885.2","go_terms":["GO:1990180","GO:0006378","GO:0001680","GO:0042245"]},{"accession":"XP_078493223.1","go_terms":["GO:0032979","GO:0015031"]}],"graph":[["XP_002122885.2","XP_002120861.4",0.765],["XP_002122885.2","XP_078485909.1",0.852],["XP_078489201.1","XP_002120861.4",0.944],["XP_078489201.1","XP_026693949.2",0.646],["XP_078489201.1","XP_078484497.1",0.785],["XP_078489201.1","XP_078485909.1",0.624],["XP_078489201.1","XP_078493786.1",0.585],["XP_009857990.2","XP_002120861.4",0.936],["XP_009857990.2","XP_009857913.2",0.849],["XP_009857990.2","XP_078485909.1",0.738],["XP_002120861.4","XP_009857913.2",0.931],["XP_002120861.4","XP_026693949.2",0.895],["XP_002120861.4","XP_026695098.2",0.963],["XP_002120861.4","XP_078484497.1",0.921],["XP_002120861.4","XP_078485909.1",0.96],["XP_002120861.4","XP_078493223.1",0.946],["XP_002120861.4","XP_078493786.1",0.936],["XP_002120861.4","XP_078494786.1",0.841],["XP_078493223.1","XP_078484497.1",0.822],["XP_078493223.1","XP_078485909.1",0.569],["XP_078493223.1","XP_078493786.1",0.63],["XP_078493786.1","XP_009857913.2",0.73],["XP_078493786.1","XP_026693949.2",0.932],["XP_078493786.1","XP_026695098.2",0.61],["XP_078493786.1","XP_078484497.1",0.601],["XP_078493786.1","XP_078485909.1",0.956],["XP_078493786.1","XP_078494786.1",0.746],["XP_026693949.2","XP_078484497.1",0.881],["XP_026693949.2","XP_078485909.1",0.731],["XP_009857913.2","XP_026695098.2",0.769],["XP_009857913.2","XP_078484497.1",0.817],["XP_009857913.2","XP_078485909.1",0.946],["XP_078485909.1","XP_026695098.2",0.742],["XP_078485909.1","XP_078484497.1",0.827],["XP_078484497.1","XP_078494786.1",0.663]],"all_go_terms":{"GO:0032784":1,"GO:0045727":1,"GO:0042273":1,"GO:0006412":3,"GO:1904803":1,"GO:0071480":1,"GO:0006354":1,"GO:1902167":1,"GO:0031564":1,"GO:0006977":1,"GO:0006353":1,"GO:1902164":1,"GO:0006784":1,"GO:0034599":1,"GO:0006515":1,"GO:0051301":1,"GO:0016558":1,"GO:0007049":1,"GO:0006796":1,"GO:0006351":1,"GO:1990001":1,"GO:2001271":1,"GO:0031503":1,"GO:0050727":1,"GO:0046673":1,"GO:0070247":1,"GO:0032465":1,"GO:1902443":1,"GO:0061469":1,"GO:0006964":1,"GO:0001890":1,"GO:0031536":1,"GO:0060712":1,"GO:0060711":1,"GO:0006915":1,"GO:0061178":1,"GO:0045035":1,"GO:0070266":1,"GO:0045849":1,"GO:0051311":1,"GO:1902523":1,"GO:1902527":1,"GO:0048800":1,"GO:1902530":1,"GO:0000278":1,"GO:0090263":1,"GO:0043123":1,"GO:0000209":1,"GO:0090307":1,"GO:1902524":1,"GO:0007059":1,"GO:0043523":1,"GO:0007058":1,"GO:0034121":1,"GO:0070146":1,"GO:0006281":1,"GO:0006310":1,"GO:0007093":1,"GO:0070154":1,"GO:0071915":1,"GO:0070200":1,"GO:0006260":1,"GO:0006422":1,"GO:0072581":1,"GO:0070145":1,"GO:0070156":1,"GO:0002101":1,"GO:0016233":1,"GO:0008033":1,"GO:0006430":1,"GO:0010833":1,"GO:0070126":1,"GO:0070125":1,"GO:0070131":1,"GO:0030007":1,"GO:0051204":1,"GO:0042407":1,"GO:0017196":1,"GO:1990180":1,"GO:0001680":1,"GO:0042245":1,"GO:0006378":1,"GO:0032979":1,"GO:0015031":1},"recipe_readded":[]}