{"hash":"1876583695098916519","title":"Spliceosome-mediated RNA processing and regulation","description":"This cluster centers on mRNA splicing via the spliceosome (positive/negative regulation, cis splicing), plus related post-transcriptional processes such as mRNA export, stabilization, and regulation of translational initiation, along with regulatory ncRNA-mediated gene silencing. Together these terms point to a cohesive theme of RNA processing and post-transcriptional control of gene expression.","confidence":"High","size":13,"edges":77,"triangles":275,"max_degree":12,"top_function":"regulatory ncRNA-mediated gene silencing","members":[{"accession":"XP_078483843.1","go_terms":["GO:0000184","GO:0071042","GO:0043629","GO:0034476","GO:0071049","GO:0071051","GO:0000472","GO:0009432","GO:1990120","GO:0048026","GO:0014070","GO:0042273","GO:0016973","GO:0070417","GO:0042255","GO:0000388","GO:0035640","GO:0006265","GO:0006260","GO:1902775","GO:1904570","GO:1903241","GO:0010501","GO:1904574","GO:0006269","GO:0034475","GO:0071031","GO:0048701","GO:0006283","GO:0071035","GO:0031124","GO:0071038","GO:0072715","GO:1990416","GO:0000462","GO:0008306","GO:0000464","GO:0018144","GO:0000466","GO:0000467","GO:1903608","GO:0000378","GO:0006310","GO:1902626","GO:0000393","GO:0000390","GO:0090394","GO:0006268","GO:0000716","GO:0000398","GO:0000463","GO:0045944","GO:0016441","GO:1990417","GO:0000480","GO:0001178","GO:0042766","GO:0006306","GO:0006301","GO:0043044","GO:0006605","GO:0070870","GO:0071441","GO:0060303","GO:0006363","GO:0006369","GO:1900050","GO:0019079","GO:0017038","GO:0071894","GO:2000616","GO:0031047","GO:0016584","GO:0006311","GO:0045003"]},{"accession":"XP_078490858.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_002123184.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_009860266.2","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_026690423.2","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:1903608","GO:0006396"]},{"accession":"XP_078491641.1","go_terms":[]},{"accession":"XP_002131514.2","go_terms":["GO:0032147","GO:0042254"]},{"accession":"XP_026694298.2","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:0071230","GO:0046011","GO:1900365","GO:0071456","GO:1900248","GO:0008069","GO:0061158","GO:0060213","GO:0007310","GO:0032869","GO:0002931","GO:0045451"]},{"accession":"XP_078483332.1","go_terms":[]},{"accession":"XP_078485221.1","go_terms":[]},{"accession":"XP_078488643.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:0071230","GO:0046011","GO:1900365","GO:0071456","GO:1900248","GO:0008069","GO:0061158","GO:0060213","GO:0007310","GO:0032869","GO:0002931","GO:0045451"]},{"accession":"XP_078488916.1","go_terms":["GO:0050766","GO:0033144","GO:0006457","GO:0030968","GO:0002502","GO:1900026","GO:2000510","GO:0090398","GO:0010204","GO:0048916","GO:1901224","GO:0007339","GO:0048387","GO:0048488","GO:0071157"]},{"accession":"XP_078491180.1","go_terms":["GO:0021785","GO:0048010","GO:1902378","GO:0021828","GO:1905040","GO:0048632","GO:0061551","GO:0021649","GO:0060672","GO:0048008","GO:0045880","GO:0036486","GO:0060978","GO:1904835","GO:0048168","GO:0007413","GO:0060385","GO:0048846","GO:0097491","GO:0097374","GO:0048843","GO:0097490","GO:1902287","GO:0001867","GO:2000312","GO:0035767","GO:0002042","GO:1902946","GO:0061441","GO:0061549","GO:0021637","GO:0021612","GO:0060074","GO:0007171","GO:0060666","GO:0048012","GO:1901166","GO:0061299","GO:0090036","GO:0018996","GO:0048842","GO:0048903","GO:1902336","GO:0060982","GO:0071679","GO:0021680","GO:1903375","GO:0007338"]}],"graph":[["XP_026690423.2","XP_002123184.1",0.848],["XP_026690423.2","XP_002131514.2",0.924],["XP_026690423.2","XP_009860266.2",0.902],["XP_026690423.2","XP_026694298.2",0.801],["XP_026690423.2","XP_078483332.1",0.938],["XP_026690423.2","XP_078483843.1",0.921],["XP_026690423.2","XP_078485221.1",0.864],["XP_026690423.2","XP_078488643.1",0.897],["XP_026690423.2","XP_078488916.1",0.778],["XP_026690423.2","XP_078490858.1",0.853],["XP_026690423.2","XP_078491180.1",0.583],["XP_002131514.2","XP_002123184.1",0.965],["XP_002131514.2","XP_009860266.2",0.918],["XP_002131514.2","XP_026694298.2",0.974],["XP_002131514.2","XP_078483332.1",0.974],["XP_002131514.2","XP_078483843.1",0.967],["XP_002131514.2","XP_078485221.1",0.961],["XP_002131514.2","XP_078488643.1",0.975],["XP_002131514.2","XP_078488916.1",0.751],["XP_002131514.2","XP_078490858.1",0.952],["XP_002131514.2","XP_078491180.1",0.982],["XP_002131514.2","XP_078491641.1",0.969],["XP_078488643.1","XP_002123184.1",0.846],["XP_078488643.1","XP_009860266.2",0.911],["XP_078488643.1","XP_026694298.2",0.929],["XP_078488643.1","XP_078483332.1",0.923],["XP_078488643.1","XP_078483843.1",0.925],["XP_078488643.1","XP_078485221.1",0.874],["XP_078488643.1","XP_078488916.1",0.941],["XP_078488643.1","XP_078490858.1",0.897],["XP_078488643.1","XP_078491180.1",0.959],["XP_078488643.1","XP_078491641.1",0.718],["XP_078483843.1","XP_002123184.1",0.844],["XP_078483843.1","XP_009860266.2",0.934],["XP_078483843.1","XP_026694298.2",0.918],["XP_078483843.1","XP_078483332.1",0.931],["XP_078483843.1","XP_078485221.1",0.904],["XP_078483843.1","XP_078488916.1",0.908],["XP_078483843.1","XP_078490858.1",0.898],["XP_078483843.1","XP_078491180.1",0.935],["XP_078483843.1","XP_078491641.1",0.88],["XP_009860266.2","XP_002123184.1",0.816],["XP_009860266.2","XP_026694298.2",0.938],["XP_009860266.2","XP_078483332.1",0.9],["XP_009860266.2","XP_078485221.1",0.865],["XP_009860266.2","XP_078488916.1",0.758],["XP_009860266.2","XP_078490858.1",0.85],["XP_009860266.2","XP_078491180.1",0.956],["XP_009860266.2","XP_078491641.1",0.788],["XP_078483332.1","XP_002123184.1",0.883],["XP_078483332.1","XP_026694298.2",0.964],["XP_078483332.1","XP_078488916.1",0.936],["XP_078483332.1","XP_078485221.1",0.895],["XP_078483332.1","XP_078491641.1",0.721],["XP_078483332.1","XP_078490858.1",0.89],["XP_078483332.1","XP_078491180.1",0.962],["XP_002123184.1","XP_026694298.2",0.837],["XP_002123184.1","XP_078488916.1",0.882],["XP_002123184.1","XP_078485221.1",0.736],["XP_002123184.1","XP_078491641.1",0.755],["XP_002123184.1","XP_078490858.1",0.867],["XP_002123184.1","XP_078491180.1",0.929],["XP_078491641.1","XP_026694298.2",0.882],["XP_078491641.1","XP_078485221.1",0.624],["XP_078491641.1","XP_078488916.1",0.867],["XP_078491641.1","XP_078490858.1",0.76],["XP_078491641.1","XP_078491180.1",0.88],["XP_026694298.2","XP_078485221.1",0.9],["XP_026694298.2","XP_078488916.1",0.908],["XP_026694298.2","XP_078490858.1",0.74],["XP_026694298.2","XP_078491180.1",0.966],["XP_078488916.1","XP_078485221.1",0.927],["XP_078488916.1","XP_078490858.1",0.831],["XP_078488916.1","XP_078491180.1",0.938],["XP_078491180.1","XP_078485221.1",0.942],["XP_078491180.1","XP_078490858.1",0.784],["XP_078490858.1","XP_078485221.1",0.888]],"all_go_terms":{"GO:0048701":1,"GO:0070870":1,"GO:0014070":1,"GO:0042766":1,"GO:2000616":1,"GO:0006301":1,"GO:0031047":6,"GO:1990120":1,"GO:0006306":1,"GO:0043629":1,"GO:0006369":2,"GO:0042255":1,"GO:0034475":1,"GO:1990417":1,"GO:0000463":1,"GO:1902775":1,"GO:0000466":1,"GO:0071038":1,"GO:0008306":1,"GO:0006310":1,"GO:0071042":1,"GO:0001178":1,"GO:0009432":1,"GO:0006268":1,"GO:0045003":1,"GO:0045944":1,"GO:0016441":1,"GO:0006605":1,"GO:1903608":2,"GO:0000480":1,"GO:0072715":1,"GO:0031124":1,"GO:0006260":1,"GO:0070417":1,"GO:1902626":1,"GO:0060303":1,"GO:0016584":1,"GO:0071049":1,"GO:0035640":1,"GO:0006265":1,"GO:0010501":1,"GO:0018144":1,"GO:0000716":1,"GO:0071894":1,"GO:0006363":1,"GO:0000378":1,"GO:0043044":1,"GO:1903241":1,"GO:0071035":1,"GO:0000388":1,"GO:0000464":1,"GO:1990416":1,"GO:0071051":1,"GO:0000390":1,"GO:0090394":1,"GO:0048026":6,"GO:0016973":1,"GO:0000184":1,"GO:1900050":1,"GO:0000398":1,"GO:0000472":1,"GO:0042273":1,"GO:0019079":1,"GO:0006311":1,"GO:0071031":1,"GO:0000393":1,"GO:0017038":1,"GO:1904570":1,"GO:0000462":1,"GO:0071441":1,"GO:0000467":1,"GO:1904574":1,"GO:0006283":1,"GO:0034476":1,"GO:0006269":1,"GO:0048025":5,"GO:1902625":5,"GO:0048255":5,"GO:0006406":5,"GO:1903586":5,"GO:0006446":5,"GO:0006378":5,"GO:1900363":5,"GO:0000380":5,"GO:1905663":5,"GO:0045292":6,"GO:0075525":5,"GO:0016556":5,"GO:0002188":5,"GO:0010610":5,"GO:0001731":5,"GO:0000381":5,"GO:0075522":5,"GO:0060211":5,"GO:0035278":5,"GO:0006376":5,"GO:0001825":5,"GO:1901407":5,"GO:0034462":5,"GO:0097010":5,"GO:0051170":1,"GO:0000290":1,"GO:0008334":1,"GO:0009737":1,"GO:0030490":1,"GO:0042633":1,"GO:0070317":1,"GO:0009414":1,"GO:0000387":1,"GO:0000245":1,"GO:0008033":1,"GO:0033962":1,"GO:1990141":1,"GO:0006396":1,"GO:0042254":1,"GO:0032147":1,"GO:0032869":2,"GO:0071456":2,"GO:1900365":2,"GO:0071230":2,"GO:1900248":2,"GO:0002931":2,"GO:0045451":2,"GO:0008069":2,"GO:0007310":2,"GO:0060213":2,"GO:0061158":2,"GO:0046011":2,"GO:1900026":1,"GO:0002502":1,"GO:0048916":1,"GO:0050766":1,"GO:2000510":1,"GO:0048387":1,"GO:0033144":1,"GO:0010204":1,"GO:0007339":1,"GO:0048488":1,"GO:1901224":1,"GO:0030968":1,"GO:0090398":1,"GO:0071157":1,"GO:0006457":1,"GO:0060982":1,"GO:1901166":1,"GO:1904835":1,"GO:0021680":1,"GO:0097491":1,"GO:0048846":1,"GO:0097490":1,"GO:0048012":1,"GO:0048010":1,"GO:0007338":1,"GO:0061551":1,"GO:0071679":1,"GO:0045880":1,"GO:1902287":1,"GO:0048903":1,"GO:0060978":1,"GO:0060666":1,"GO:0097374":1,"GO:1902378":1,"GO:0060074":1,"GO:0036486":1,"GO:0007171":1,"GO:1902336":1,"GO:0048168":1,"GO:0021828":1,"GO:0048843":1,"GO:0060672":1,"GO:0001867":1,"GO:2000312":1,"GO:0021637":1,"GO:0061299":1,"GO:0048008":1,"GO:0060385":1,"GO:1902946":1,"GO:0007413":1,"GO:0035767":1,"GO:0048842":1,"GO:0048632":1,"GO:0021785":1,"GO:0002042":1,"GO:0021649":1,"GO:0018996":1,"GO:0061441":1,"GO:0061549":1,"GO:0090036":1,"GO:1903375":1,"GO:0021612":1,"GO:1905040":1},"recipe_readded":[]}