{"hash":"2034994439206218694","title":"One-carbon metabolism and nucleotide synthesis","description":"This cluster shows strong representation of one-carbon metabolic processes (one-carbon metabolic process; tetrahydrofolate biosynthesis; tetrahydrobiopterin biosynthesis) and nucleotide production (thymidine biosynthetic process). These GO terms together suggest a shared role in supplying one-carbon units and cofactors for nucleotide biosynthesis, with a possible link to NOS regulation via BH4, while other terms like axon regeneration or drug response might be less central or incidental to this core metabolic theme. Confidence reflects the clear core of metabolism-related terms despite some noise.","confidence":"Medium","size":3,"edges":3,"triangles":1,"max_degree":2,"top_function":null,"members":[{"accession":"XP_041041480.1","go_terms":["GO:0006730","GO:0000083","GO:0051000","GO:0046655","GO:0046654","GO:0006545","GO:0032259","GO:0006729","GO:0031103","GO:0046105","GO:0055114","GO:2000121","GO:0006231","GO:0031427","GO:0046452","GO:0046677"]},{"accession":"XP_041071451.1","go_terms":["GO:0006730","GO:0000083","GO:0051000","GO:0046655","GO:0046654","GO:0006545","GO:0032259","GO:0006729","GO:0031103","GO:0046105","GO:0055114","GO:2000121","GO:0006231","GO:0031427","GO:0046452","GO:0046677"]},{"accession":"XP_041048201.1","go_terms":["GO:0006738","GO:0006218","GO:0046638","GO:0034356","GO:0009166","GO:0042149","GO:0019284","GO:0046115","GO:0070970","GO:0019509","GO:0044209","GO:0019686","GO:0044206","GO:0009234","GO:0006148","GO:0006161","GO:0006166","GO:0034418","GO:0019358"]}],"graph":[["XP_041041480.1","XP_041071451.1",0.856],["XP_041041480.1","XP_041048201.1",0.96],["XP_041071451.1","XP_041048201.1",0.865]],"all_go_terms":{"GO:0051000":2,"GO:0031103":2,"GO:0046654":2,"GO:0046105":2,"GO:0000083":2,"GO:0031427":2,"GO:0046677":2,"GO:0006729":2,"GO:0055114":2,"GO:0006730":2,"GO:0032259":2,"GO:2000121":2,"GO:0046655":2,"GO:0046452":2,"GO:0006231":2,"GO:0006545":2,"GO:0034418":1,"GO:0046638":1,"GO:0009234":1,"GO:0042149":1,"GO:0046115":1,"GO:0019358":1,"GO:0006166":1,"GO:0009166":1,"GO:0019284":1,"GO:0044206":1,"GO:0006218":1,"GO:0044209":1,"GO:0006161":1,"GO:0019686":1,"GO:0034356":1,"GO:0006738":1,"GO:0019509":1,"GO:0006148":1,"GO:0070970":1},"recipe_readded":[]}