{"hash":"851375223599478695","title":"Mitochondrial apoptosis and cytokine production","description":"The top GO terms point to regulation of mitochondrial-mediated apoptosis (negative regulation of mitochondrial depolarization, cytochrome c release, and extrinsic pathway regulation) and production of inflammatory cytokines IL-1\u03b2 and IL-18. Some terms involve membrane trafficking and neural-related processes, suggesting broader cellular stress responses, but the strongest signal is apoptosis control linked to inflammatory signaling. ","confidence":"Medium","size":10,"edges":9,"triangles":0,"max_degree":9,"top_function":null,"members":[{"accession":"XP_040079207.1","go_terms":["GO:0043154","GO:2001240","GO:0001836","GO:0051902"]},{"accession":"XP_040075599.1","go_terms":["GO:1900017","GO:0007030","GO:0071346","GO:0051260","GO:0072616","GO:0008582","GO:1900025","GO:0016320","GO:0007019","GO:0050702","GO:0071158","GO:0051124","GO:1900227","GO:0007029","GO:0045687","GO:1900041"]},{"accession":"XP_029823645.1","go_terms":["GO:0048280","GO:0048279","GO:0016320"]},{"accession":"XP_002433394.2","go_terms":[]},{"accession":"XP_029831288.1","go_terms":[]},{"accession":"XP_002401273.2","go_terms":["GO:0000002","GO:0030150","GO:0045039","GO:0032094","GO:0045037"]},{"accession":"XP_040361198.1","go_terms":[]},{"accession":"XP_029841337.2","go_terms":["GO:0046688"]},{"accession":"XP_040072114.1","go_terms":["GO:0006777","GO:0009688","GO:0006727","GO:0018315","GO:0010118","GO:0045037"]},{"accession":"XP_002410268.4","go_terms":[]}],"graph":[["XP_029841337.2","XP_040075599.1",0.677],["XP_040072114.1","XP_040075599.1",0.5],["XP_002433394.2","XP_040075599.1",0.697],["XP_029831288.1","XP_040075599.1",0.549],["XP_040075599.1","XP_040079207.1",0.715],["XP_040075599.1","XP_040361198.1",0.704],["XP_040075599.1","XP_002401273.2",0.539],["XP_040075599.1","XP_002410268.4",0.575],["XP_040075599.1","XP_029823645.1",0.704]],"all_go_terms":{"GO:0051902":1,"GO:0043154":1,"GO:2001240":1,"GO:0001836":1,"GO:0045687":1,"GO:0008582":1,"GO:0050702":1,"GO:0072616":1,"GO:0007030":1,"GO:0016320":2,"GO:0007019":1,"GO:1900017":1,"GO:0071346":1,"GO:1900041":1,"GO:0051124":1,"GO:1900227":1,"GO:0071158":1,"GO:0051260":1,"GO:1900025":1,"GO:0007029":1,"GO:0048280":1,"GO:0048279":1,"GO:0000002":1,"GO:0045037":2,"GO:0030150":1,"GO:0045039":1,"GO:0032094":1,"GO:0046688":1,"GO:0006777":1,"GO:0009688":1,"GO:0010118":1,"GO:0006727":1,"GO:0018315":1},"recipe_readded":[]}