{"hash":"2292203715513656914","title":"GPCR-Mediated Neuroendocrine Signaling","description":"The cluster shows GO terms tied to GPCR-driven signaling and hormone responses, including dopamine receptor signaling (adenylate cyclase pathway), glucagon- and prostaglandin-responsive signaling, and regulation of insulin secretion, plus sensory and balance-related processes (smell and neuromuscular balance) and a link to the secretory pathway (ER to Golgi transport). This suggests a cohesive theme around neuroendocrine GPCR signaling and secretion rather than unrelated functions.","confidence":"Medium","size":8,"edges":8,"triangles":0,"max_degree":6,"top_function":null,"members":[{"accession":"XP_042147405.1","go_terms":["GO:1904322","GO:0007616","GO:0071380","GO:0007591","GO:0034199","GO:0035556","GO:0010353","GO:0090328","GO:0008355","GO:0007340","GO:0050885","GO:0003091","GO:0001582","GO:0035811","GO:0006171","GO:0007608","GO:0001661","GO:0071870","GO:0061178","GO:0006182","GO:0071361","GO:0071377","GO:0016199","GO:0001973","GO:1904117","GO:0007191","GO:0007190","GO:0007195","GO:0052565","GO:0009785","GO:0007168","GO:0070483","GO:1900194","GO:0030828","GO:0006355","GO:0071880"]},{"accession":"XP_002405925.1","go_terms":["GO:0040027","GO:0006888"]},{"accession":"XP_040064236.1","go_terms":[]},{"accession":"XP_029839450.1","go_terms":[]},{"accession":"XP_040065928.1","go_terms":["GO:0039021"]},{"accession":"XP_002414760.3","go_terms":["GO:0042552","GO:0043652","GO:0031133","GO:0048741","GO:0070782","GO:0010961"]},{"accession":"XP_040072757.1","go_terms":["GO:0006888","GO:0006486","GO:0031505","GO:0045053"]},{"accession":"XP_040076945.1","go_terms":["GO:0098719","GO:1902600","GO:1903281","GO:0030007","GO:0051595","GO:0031547","GO:0009651","GO:0097623","GO:0007035","GO:0006884","GO:0036376","GO:0086092"]}],"graph":[["XP_040065928.1","XP_040072757.1",0.706],["XP_040065928.1","XP_040076945.1",0.82],["XP_040065928.1","XP_042147405.1",0.565],["XP_040065928.1","XP_002405925.1",0.944],["XP_040065928.1","XP_002414760.3",0.773],["XP_040065928.1","XP_040064236.1",0.624],["XP_002405925.1","XP_029839450.1",0.773],["XP_029839450.1","XP_042147405.1",0.901]],"all_go_terms":{"GO:0006355":1,"GO:0061178":1,"GO:0050885":1,"GO:0071377":1,"GO:0007608":1,"GO:0007195":1,"GO:0035811":1,"GO:0009785":1,"GO:0071380":1,"GO:0008355":1,"GO:0030828":1,"GO:0007591":1,"GO:0090328":1,"GO:1904322":1,"GO:0007168":1,"GO:0001582":1,"GO:0006171":1,"GO:0003091":1,"GO:0071870":1,"GO:0052565":1,"GO:0035556":1,"GO:0071880":1,"GO:0034199":1,"GO:0010353":1,"GO:1900194":1,"GO:0071361":1,"GO:0016199":1,"GO:0001973":1,"GO:0007191":1,"GO:0007616":1,"GO:0007340":1,"GO:0006182":1,"GO:0070483":1,"GO:0001661":1,"GO:1904117":1,"GO:0007190":1,"GO:0040027":1,"GO:0006888":2,"GO:0039021":1,"GO:0043652":1,"GO:0042552":1,"GO:0048741":1,"GO:0031133":1,"GO:0010961":1,"GO:0070782":1,"GO:0031505":1,"GO:0045053":1,"GO:0006486":1,"GO:0098719":1,"GO:1903281":1,"GO:0086092":1,"GO:1902600":1,"GO:0051595":1,"GO:0007035":1,"GO:0097623":1,"GO:0030007":1,"GO:0009651":1,"GO:0031547":1,"GO:0036376":1,"GO:0006884":1},"recipe_readded":[]}