{"hash":"1959049198986622016","title":"Ubiquitin-Dependent Regulation and NF-kappaB Signaling","description":"Most of the top terms center on ubiquitination and ubiquitin-mediated proteolysis (ubiquitin-dependent protein catabolic process, polyubiquitination, K48-linked ubiquitination, histone ubiquitination), with several terms tying to NF-kappaB pathway activation (IKK activity, I-kappaB phosphorylation). This suggests a theme of ubiquitin-driven protein turnover and signaling that feeds into NF-kappaB regulation, though a few terms (peroxisome import, histone acetylation regulation) are less cohesive with the main pattern.","confidence":"Medium","size":12,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_029833982.2","go_terms":[]},{"accession":"XP_040072092.1","go_terms":[]},{"accession":"XP_029839500.3","go_terms":[]},{"accession":"XP_040073914.1","go_terms":[]},{"accession":"XP_040066576.1","go_terms":[]},{"accession":"XP_040069540.1","go_terms":[]},{"accession":"XP_002411343.3","go_terms":["GO:0038018","GO:0016558","GO:0030433","GO:0060816","GO:0051865","GO:0042787","GO:0046621","GO:1900095","GO:0070936","GO:0060544","GO:0000122","GO:0034121","GO:0043066","GO:0000209","GO:0071157","GO:0033151","GO:0033209","GO:0009048","GO:0036205","GO:0046328","GO:2000620","GO:0042981","GO:0007250","GO:0070512","GO:0085020","GO:0070535","GO:1903265","GO:1903762","GO:1903721","GO:1901253","GO:0090073"]},{"accession":"XP_040061679.1","go_terms":["GO:0010018","GO:0006355","GO:0042753","GO:0009585"]},{"accession":"XP_040061738.1","go_terms":[]},{"accession":"XP_040069421.1","go_terms":[]},{"accession":"XP_042147211.1","go_terms":[]},{"accession":"XP_042148657.1","go_terms":[]}],"graph":[],"all_go_terms":{"GO:0042787":1,"GO:0070535":1,"GO:2000620":1,"GO:0007250":1,"GO:0051865":1,"GO:0000209":1,"GO:0036205":1,"GO:1903721":1,"GO:0070936":1,"GO:0016558":1,"GO:1903265":1,"GO:0046328":1,"GO:0070512":1,"GO:0038018":1,"GO:0046621":1,"GO:0090073":1,"GO:0009048":1,"GO:0060816":1,"GO:0060544":1,"GO:0071157":1,"GO:1903762":1,"GO:0033151":1,"GO:0042981":1,"GO:1900095":1,"GO:1901253":1,"GO:0034121":1,"GO:0000122":1,"GO:0033209":1,"GO:0085020":1,"GO:0043066":1,"GO:0030433":1,"GO:0006355":1,"GO:0009585":1,"GO:0010018":1,"GO:0042753":1},"recipe_readded":["XP_002403086.2","XP_029827327.2"]}