{"hash":"1825365076673734579","title":"Central metabolism and lipid biosynthesis","description":"The cluster is enriched for several biosynthetic and metabolic processes, notably NAD+ and polyamine biosynthesis, oxaloacetate metabolism, lipoprotein biosynthesis, and regulation of cholesterol biosynthesis, which points to lipid-related metabolism as a core theme. The ER-to-Golgi vesicle transport term supports lipid/protein trafficking needed for lipoprotein assembly, while mitochondrial inheritance aligns with energy-related organization. Together, these terms suggest a cohesive group centered on metabolic biosynthesis with a focus on lipids and energy metabolism, with some ancillary trafficking and stress-related terms accompanying them.","confidence":"Medium","size":24,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_029842732.2","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]},{"accession":"XP_042149546.1","go_terms":["GO:0001576","GO:0036210","GO:0051999"]},{"accession":"XP_029832331.1","go_terms":[]},{"accession":"XP_040063073.1","go_terms":[]},{"accession":"XP_029834468.2","go_terms":["GO:0001949","GO:0032286","GO:0006636","GO:0000001","GO:0032443","GO:0006675","GO:0042128","GO:0006809"]},{"accession":"XP_029840128.1","go_terms":["GO:0005975","GO:0006487"]},{"accession":"XP_040358151.1","go_terms":[]},{"accession":"XP_002412473.2","go_terms":["GO:0002642","GO:0009951","GO:0032367","GO:0030917","GO:2001274","GO:0007311","GO:0033622"]},{"accession":"XP_002409909.1","go_terms":[]},{"accession":"XP_029847548.1","go_terms":["GO:0002037","GO:0006888","GO:0008631","GO:0010917"]},{"accession":"XP_040063213.1","go_terms":[]},{"accession":"XP_029824496.2","go_terms":[]},{"accession":"XP_029850859.2","go_terms":[]},{"accession":"XP_002411593.1","go_terms":["GO:0006888","GO:0042147","GO:0015031"]},{"accession":"XP_002402519.3","go_terms":["GO:0010143","GO:0045347","GO:0002643","GO:0039648","GO:0002495","GO:0000209","GO:1900490","GO:0010345","GO:0039504"]},{"accession":"XP_029844409.2","go_terms":[]},{"accession":"XP_040358039.2","go_terms":["GO:0006596","GO:0009435","GO:0006107","GO:0046686","GO:0042158"]},{"accession":"XP_040067246.1","go_terms":[]},{"accession":"XP_040073520.1","go_terms":["GO:0006596","GO:0009435","GO:0006107","GO:0046686","GO:0042158"]},{"accession":"XP_040077840.2","go_terms":["GO:0006067","GO:0061668"]},{"accession":"XP_042144997.1","go_terms":[]},{"accession":"XP_002414390.3","go_terms":["GO:0040003","GO:0072606","GO:0030324","GO:0018990","GO:0007250","GO:0071347","GO:0006915","GO:0009612","GO:0000272","GO:0051216","GO:0006032","GO:0070741"]},{"accession":"XP_029829362.4","go_terms":[]},{"accession":"XP_029842212.2","go_terms":["GO:1904721","GO:1990441","GO:1902065","GO:1902045","GO:0060702","GO:1902236","GO:1902042","GO:1903298","GO:0032469","GO:0051025","GO:0090005","GO:0021681","GO:0021702","GO:0010523"]}],"graph":[],"all_go_terms":{"GO:0001302":1,"GO:2000049":1,"GO:0045541":1,"GO:1990046":1,"GO:0072249":1,"GO:0034141":1,"GO:0007588":1,"GO:0032226":1,"GO:0022617":1,"GO:0010918":1,"GO:0010876":1,"GO:0052547":1,"GO:0000001":2,"GO:0032933":1,"GO:0090297":1,"GO:1903905":1,"GO:1900210":1,"GO:0045861":1,"GO:0007007":1,"GO:0070528":1,"GO:1903044":1,"GO:0070584":1,"GO:1901585":1,"GO:0032623":1,"GO:0060355":1,"GO:0030433":1,"GO:0036210":1,"GO:0001576":1,"GO:0051999":1,"GO:0006636":1,"GO:0006675":1,"GO:0042128":1,"GO:0032286":1,"GO:0001949":1,"GO:0006809":1,"GO:0032443":1,"GO:0006487":1,"GO:0005975":1,"GO:0032367":1,"GO:0007311":1,"GO:0009951":1,"GO:0033622":1,"GO:0002642":1,"GO:0030917":1,"GO:2001274":1,"GO:0008631":1,"GO:0010917":1,"GO:0006888":2,"GO:0002037":1,"GO:0015031":1,"GO:0042147":1,"GO:0039648":1,"GO:0039504":1,"GO:0010143":1,"GO:0010345":1,"GO:0002495":1,"GO:0045347":1,"GO:0000209":1,"GO:1900490":1,"GO:0002643":1,"GO:0009435":2,"GO:0006596":2,"GO:0006107":2,"GO:0046686":2,"GO:0042158":2,"GO:0006067":1,"GO:0061668":1,"GO:0006032":1,"GO:0072606":1,"GO:0007250":1,"GO:0071347":1,"GO:0040003":1,"GO:0051216":1,"GO:0006915":1,"GO:0070741":1,"GO:0030324":1,"GO:0009612":1,"GO:0000272":1,"GO:0018990":1,"GO:0032469":1,"GO:1904721":1,"GO:1990441":1,"GO:0090005":1,"GO:1902042":1,"GO:0010523":1,"GO:0060702":1,"GO:0021681":1,"GO:0051025":1,"GO:1902065":1,"GO:1902045":1,"GO:1902236":1,"GO:1903298":1,"GO:0021702":1},"recipe_readded":["XP_029829874.2","XP_002408002.1","XP_040070044.2","XP_040354729.2","XP_029839469.1","XP_040358023.1","XP_029835672.2","XP_042146639.1","XP_040061322.1","XP_002411894.3","XP_029850946.2","XP_029839655.3","XP_040355636.1","XP_002402926.2","XP_040062818.2","XP_040062835.3","XP_040355317.2","XP_029841802.2","XP_040066152.2","XP_042142264.1"]}