{"hash":"1471320339798516861","title":"Viral DNA Integration and Proviral Latency","description":"The top GO terms cluster around viral entry, nuclear penetration, DNA replication and integration, establishment of proviral latency, and reverse transcription\u2013related DNA synthesis, all hallmark features of retroviral life cycles and provirus maintenance. Additional terms about DNA recombination and transposition support a broader theme of mobile genetic element activity and viral manipulation of the host, with some host defense interactions (siRNA processing). This combination points to a cohesive theme of viral genome integration and latent provirus maintenance.","confidence":"High","size":6,"edges":0,"triangles":0,"max_degree":0,"top_function":"DNA replication","members":[{"accession":"XP_042143067.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704","GO:0006313","GO:0032197"]},{"accession":"XP_042144656.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704","GO:0006313","GO:0032197","GO:0097043"]},{"accession":"XP_040069342.2","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"XP_042145134.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704","GO:0000122","GO:0006351","GO:1900112","GO:0071031","GO:0010587","GO:0019076","GO:0019068","GO:0039702","GO:0000398","GO:0030260","GO:0006508"]},{"accession":"XP_042147535.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704","GO:0006313","GO:0032197"]},{"accession":"XP_042143898.1","go_terms":["GO:0015074","GO:0006310","GO:0046718","GO:0019076","GO:0075713","GO:0075732","GO:0006508","GO:0039651","GO:0039657","GO:0006278","GO:0006260","GO:1903704","GO:0006313","GO:0032197"]}],"graph":[],"all_go_terms":{"GO:0046718":6,"GO:0075732":6,"GO:0006260":6,"GO:0075713":6,"GO:0006310":6,"GO:0006313":4,"GO:0015074":6,"GO:1903704":6,"GO:0039651":6,"GO:0032197":4,"GO:0006278":6,"GO:0097043":1,"GO:0019068":1,"GO:0030260":1,"GO:0010587":1,"GO:0019076":2,"GO:0006351":1,"GO:0000398":1,"GO:0071031":1,"GO:1900112":1,"GO:0006508":2,"GO:0000122":1,"GO:0039702":1,"GO:0039657":1},"recipe_readded":["XP_040065225.1","XP_042146078.1","XP_029850880.3","XP_002435161.1","XP_002402192.1","XP_040065233.1","XP_002408525.1"]}