{"hash":"910207718104655311","title":"Proteostasis and Cytoskeleton Maintenance","description":"The cluster is enriched for protein folding and chaperone-related terms (protein folding, chaperone-mediated complex assembly), proteostasis quality control (ubiquitin-proteasome system, macroautophagy regulation), and cytoskeletal organization (tubulin complex assembly, cortical microtubule organization). While some transcription-related terms appear, the strongest signal centers on maintaining protein homeostasis and cytoskeletal assembly, suggesting a functional module for proteostasis coupled to cytoskeleton maintenance.","confidence":"Medium","size":10,"edges":21,"triangles":19,"max_degree":7,"top_function":"protein folding","members":[{"accession":"XP_040554810.1","go_terms":["GO:0061635","GO:0016239"]},{"accession":"NP_001108324.1","go_terms":["GO:0061635","GO:0016239"]},{"accession":"XP_004938433.1","go_terms":[]},{"accession":"XP_024998759.2","go_terms":["GO:0044154","GO:0043968","GO:0043983","GO:0043981","GO:0043982","GO:0006355","GO:0006351"]},{"accession":"XP_040502806.1","go_terms":["GO:0007021","GO:0051131","GO:0006457","GO:0071629","GO:0032968","GO:0043622"]},{"accession":"NP_001264076.1","go_terms":["GO:0007021","GO:0051131","GO:0006457","GO:0071629","GO:0032968","GO:0043622"]},{"accession":"XP_001234484.1","go_terms":[]},{"accession":"NP_001384045.1","go_terms":["GO:0007021","GO:1990115","GO:1990114","GO:0006457","GO:0031137","GO:1990113","GO:0032968"]},{"accession":"XP_015151961.2","go_terms":["GO:0007021","GO:0051131","GO:0006457","GO:0071629","GO:0032968","GO:0043622"]},{"accession":"XP_046754725.1","go_terms":[]}],"graph":[["NP_001108324.1","XP_001234484.1",0.726],["NP_001108324.1","XP_004938433.1",0.849],["NP_001108324.1","XP_015151961.2",0.587],["NP_001108324.1","XP_040502806.1",0.596],["NP_001108324.1","XP_040554810.1",0.504],["NP_001108324.1","XP_046754725.1",0.766],["XP_004938433.1","XP_046754725.1",0.744],["XP_004938433.1","XP_001234484.1",0.782],["XP_004938433.1","XP_015151961.2",0.654],["XP_046754725.1","XP_001234484.1",0.741],["XP_046754725.1","XP_015151961.2",0.666],["XP_046754725.1","XP_040554810.1",0.645],["XP_046754725.1","NP_001384045.1",0.81],["NP_001384045.1","XP_001234484.1",0.875],["NP_001384045.1","XP_015151961.2",0.751],["NP_001384045.1","XP_024998759.2",0.617],["XP_015151961.2","XP_024998759.2",0.852],["XP_015151961.2","XP_040502806.1",0.596],["XP_015151961.2","XP_001234484.1",0.812],["XP_001234484.1","XP_024998759.2",0.729],["XP_024998759.2","XP_040502806.1",0.527]],"all_go_terms":{"GO:0061635":2,"GO:0016239":2,"GO:0043981":1,"GO:0006351":1,"GO:0006355":1,"GO:0043983":1,"GO:0043982":1,"GO:0043968":1,"GO:0044154":1,"GO:0032968":4,"GO:0006457":4,"GO:0051131":3,"GO:0043622":3,"GO:0007021":4,"GO:0071629":3,"GO:1990115":1,"GO:0031137":1,"GO:1990114":1,"GO:1990113":1},"recipe_readded":[]}