{"hash":"648991800288858267","title":"Developmental Differentiation and DNA Endoreduplication","description":"This cluster combines terms tied to developmental processes (forebrain development, sprouting angiogenesis, trophoblast giant cell differentiation) with DNA-centric processes (DNA-templated transcription, DNA endoreduplication and its positive regulation, and apoptotic signaling in response to DNA damage). The overlap suggests proteins involved in developmental differentiation that also regulate DNA replication dynamics and stress responses, including endoreduplication. Some plant-specific terms (glucosinolate metabolism) may reflect cross-species annotations but do not undermine the core theme.","confidence":"Medium","size":5,"edges":8,"triangles":5,"max_degree":4,"top_function":"mitotic cell cycle","members":[{"accession":"XP_015131434.1","go_terms":["GO:0060718","GO:0043276","GO:0048146","GO:0008069","GO:0072332","GO:2000134","GO:0030330","GO:0001946","GO:0008015","GO:0030900","GO:0032466","GO:0002040","GO:0070365","GO:0045850","GO:0070345","GO:1990086","GO:0060707","GO:0019760","GO:0042023","GO:0032877","GO:0048255","GO:0071930","GO:0008630","GO:0071466","GO:0045944","GO:0006351","GO:0033301","GO:0043392","GO:0045599","GO:0000278","GO:0051726","GO:0006884"]},{"accession":"XP_015131436.1","go_terms":["GO:0060718","GO:0043276","GO:0048146","GO:0008069","GO:0072332","GO:2000134","GO:0030330","GO:0001946","GO:0008015","GO:0030900","GO:0032466","GO:0002040","GO:0070365","GO:0045850","GO:0070345","GO:1990086","GO:0060707","GO:0019760","GO:0042023","GO:0032877","GO:0048255","GO:0071930","GO:0008630","GO:0071466","GO:0045944","GO:0006351","GO:0033301","GO:0043392","GO:0045599","GO:0000278","GO:0051726","GO:0006884"]},{"accession":"XP_040507918.1","go_terms":["GO:0060718","GO:0043276","GO:0048146","GO:0008069","GO:0072332","GO:2000134","GO:0030330","GO:0001946","GO:0008015","GO:0030900","GO:0032466","GO:0002040","GO:0070365","GO:0045850","GO:0070345","GO:1990086","GO:0060707","GO:0019760","GO:0042023","GO:0032877","GO:0048255","GO:0071930","GO:0008630","GO:0071466","GO:0045944","GO:0006351","GO:0033301","GO:0043392","GO:0045599","GO:0000278","GO:0051726","GO:0006884"]},{"accession":"XP_046797874.1","go_terms":["GO:0051123","GO:1903357","GO:0006413","GO:0070893","GO:0007283","GO:0045893","GO:0006352","GO:0042790","GO:0070898","GO:0006383","GO:0006359"]},{"accession":"NP_001376562.1","go_terms":["GO:0045746","GO:0000183","GO:0031937","GO:1902231","GO:0034773","GO:0098532","GO:1900477","GO:0080182","GO:0036124"]}],"graph":[["XP_015131436.1","XP_040507918.1",0.736],["XP_015131436.1","XP_046797874.1",0.778],["XP_015131436.1","XP_015131434.1",0.749],["NP_001376562.1","XP_040507918.1",0.554],["NP_001376562.1","XP_046797874.1",0.788],["XP_015131434.1","XP_040507918.1",0.715],["XP_015131434.1","XP_046797874.1",0.715],["XP_040507918.1","XP_046797874.1",0.791]],"all_go_terms":{"GO:0030900":3,"GO:0006351":3,"GO:0060707":3,"GO:0008630":3,"GO:0042023":3,"GO:0002040":3,"GO:0071930":3,"GO:0019760":3,"GO:0071466":3,"GO:0032877":3,"GO:0045599":3,"GO:0051726":3,"GO:0070365":3,"GO:0006884":3,"GO:0008069":3,"GO:0072332":3,"GO:0008015":3,"GO:0048255":3,"GO:0045850":3,"GO:0030330":3,"GO:0043276":3,"GO:0000278":3,"GO:0048146":3,"GO:1990086":3,"GO:0043392":3,"GO:0045944":3,"GO:0001946":3,"GO:0033301":3,"GO:0070345":3,"GO:0032466":3,"GO:2000134":3,"GO:0060718":3,"GO:0042790":1,"GO:0006352":1,"GO:0051123":1,"GO:0070893":1,"GO:0006359":1,"GO:0006383":1,"GO:0006413":1,"GO:0070898":1,"GO:0045893":1,"GO:0007283":1,"GO:1903357":1,"GO:0080182":1,"GO:0098532":1,"GO:0034773":1,"GO:0045746":1,"GO:1900477":1,"GO:0036124":1,"GO:0000183":1,"GO:1902231":1,"GO:0031937":1},"recipe_readded":[]}