{"hash":"483973806796707204","title":"Ion transport and membrane homeostasis","description":"The cluster is dominated by GO terms related to membrane ion transport and homeostasis, including sodium and potassium import/export, intracellular potassium balance, proton transmembrane transport, vacuolar acidification, and cell volume regulation. These suggest a set of transporter and pump proteins governing cellular excitability and ionic balance, with a tangential reference to brain-derived neurotrophic factor receptor signaling. Overall, the common theme is membrane ion transport and ionic homeostasis with related signaling facets.","confidence":"Medium","size":12,"edges":29,"triangles":24,"max_degree":7,"top_function":null,"members":[{"accession":"XP_015151899.1","go_terms":["GO:0098719","GO:1902600","GO:1903281","GO:0030007","GO:0051595","GO:0031547","GO:0009651","GO:0097623","GO:0007035","GO:0006884","GO:0036376","GO:0086092"]},{"accession":"XP_015155452.1","go_terms":["GO:0010312","GO:0070574","GO:0060173","GO:0006882","GO:0006831","GO:0006830","GO:0044749","GO:0034224","GO:1903615"]},{"accession":"NP_001034364.2","go_terms":["GO:0098719","GO:1902600","GO:1903281","GO:0030007","GO:0051595","GO:0031547","GO:0009651","GO:0097623","GO:0007035","GO:0006884","GO:0036376","GO:0086092"]},{"accession":"XP_015133242.2","go_terms":["GO:0098719","GO:1902600","GO:1903281","GO:0030007","GO:0051595","GO:0031547","GO:0009651","GO:0097623","GO:0007035","GO:0006884","GO:0036376","GO:0086092"]},{"accession":"XP_015151900.1","go_terms":["GO:0098719","GO:1902600","GO:1903281","GO:0030007","GO:0051595","GO:0031547","GO:0009651","GO:0097623","GO:0007035","GO:0006884","GO:0036376","GO:0086092"]},{"accession":"XP_040517861.1","go_terms":["GO:0098719","GO:1902600","GO:1903281","GO:0030007","GO:0051595","GO:0031547","GO:0009651","GO:0097623","GO:0007035","GO:0006884","GO:0036376","GO:0086092"]},{"accession":"XP_040552256.1","go_terms":["GO:0098719","GO:1902600","GO:1903281","GO:0030007","GO:0051595","GO:0031547","GO:0009651","GO:0097623","GO:0007035","GO:0006884","GO:0036376","GO:0086092"]},{"accession":"NP_001026476.1","go_terms":["GO:0098719","GO:1902600","GO:1903281","GO:0030007","GO:0051595","GO:0031547","GO:0009651","GO:0097623","GO:0007035","GO:0006884","GO:0036376","GO:0086092"]},{"accession":"XP_420258.3","go_terms":["GO:0098719","GO:1902600","GO:1903281","GO:0030007","GO:0051595","GO:0031547","GO:0009651","GO:0097623","GO:0007035","GO:0006884","GO:0036376","GO:0086092","GO:0098735","GO:0035794","GO:0070886","GO:0051453","GO:0035994","GO:0071436","GO:0042539","GO:0071805","GO:0045760","GO:0006883","GO:0002064","GO:0071236","GO:0071257","GO:0055007","GO:0010613","GO:0086003","GO:0051533","GO:0010882","GO:0001696","GO:0071468","GO:0071872"]},{"accession":"XP_426562.2","go_terms":["GO:0010312","GO:0070574","GO:0060173","GO:0006882","GO:0006831","GO:0006830","GO:0044749","GO:0034224","GO:1903615"]},{"accession":"XP_015133960.3","go_terms":["GO:0098719","GO:1902600","GO:1903281","GO:0030007","GO:0051595","GO:0031547","GO:0009651","GO:0097623","GO:0007035","GO:0006884","GO:0036376","GO:0086092"]},{"accession":"XP_419071.3","go_terms":["GO:0010312","GO:0070574","GO:0060173","GO:0006882","GO:0006831","GO:0006830","GO:0044749","GO:0034224","GO:1903615"]}],"graph":[["XP_015133242.2","XP_040517861.1",0.614],["XP_015133242.2","XP_420258.3",0.533],["XP_015133242.2","NP_001026476.1",0.569],["XP_015133242.2","XP_015133960.3",0.575],["NP_001026476.1","NP_001034364.2",0.514],["NP_001026476.1","XP_015133960.3",0.598],["NP_001026476.1","XP_040517861.1",0.58],["NP_001026476.1","XP_015151899.1",0.5],["XP_015133960.3","XP_040517861.1",0.549],["XP_015133960.3","XP_420258.3",0.532],["XP_419071.3","XP_015151899.1",0.502],["XP_419071.3","XP_015151900.1",0.508],["XP_419071.3","XP_015155452.1",0.761],["XP_419071.3","XP_040517861.1",0.507],["XP_419071.3","NP_001034364.2",0.594],["XP_015155452.1","XP_015151899.1",0.514],["XP_015155452.1","XP_015151900.1",0.617],["XP_015155452.1","XP_426562.2",0.658],["XP_015155452.1","NP_001034364.2",0.511],["XP_040552256.1","XP_015151899.1",0.501],["XP_040552256.1","XP_420258.3",0.509],["XP_040552256.1","NP_001034364.2",0.504],["XP_015151900.1","XP_015151899.1",0.615],["XP_015151900.1","XP_420258.3",0.524],["XP_015151900.1","NP_001034364.2",0.553],["XP_420258.3","XP_015151899.1",0.554],["XP_420258.3","XP_040517861.1",0.508],["XP_420258.3","NP_001034364.2",0.534],["XP_015151899.1","NP_001034364.2",0.543]],"all_go_terms":{"GO:0031547":9,"GO:0098719":9,"GO:0097623":9,"GO:0009651":9,"GO:0007035":9,"GO:0006884":9,"GO:0030007":9,"GO:0036376":9,"GO:0086092":9,"GO:1902600":9,"GO:0051595":9,"GO:1903281":9,"GO:0044749":3,"GO:0060173":3,"GO:0006882":3,"GO:1903615":3,"GO:0006831":3,"GO:0034224":3,"GO:0010312":3,"GO:0070574":3,"GO:0006830":3,"GO:0051453":1,"GO:0071468":1,"GO:0071236":1,"GO:0010613":1,"GO:0071872":1,"GO:0071257":1,"GO:0051533":1,"GO:0045760":1,"GO:0070886":1,"GO:0001696":1,"GO:0035794":1,"GO:0035994":1,"GO:0002064":1,"GO:0071805":1,"GO:0086003":1,"GO:0042539":1,"GO:0006883":1,"GO:0098735":1,"GO:0071436":1,"GO:0055007":1,"GO:0010882":1},"recipe_readded":[]}