{"hash":"467705196176973571","title":"RNA Splicing and Translational Regulation","description":"The top GO terms cluster around mRNA splicing via the spliceosome (including splice-site recognition and alternative splicing) and small-subunit processome components, with additional signals of translational control (IRES-dependent initiation and regulation of translational initiation) and regulatory ncRNA\u2013mediated silencing. This points to a coherent module linking RNA processing/splicing to regulation of translation.","confidence":"High","size":10,"edges":44,"triangles":112,"max_degree":9,"top_function":"regulatory ncRNA-mediated gene silencing","members":[{"accession":"NP_001264651.1","go_terms":["GO:0000387","GO:0000245"]},{"accession":"XP_015146289.3","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_040561973.1","go_terms":["GO:0032762","GO:1901899","GO:0002551","GO:1905183","GO:0050930","GO:0033604","GO:2000352","GO:0050830","GO:0052338","GO:0050829","GO:0048245","GO:0001525","GO:0086030","GO:0043303","GO:0001938","GO:2001237","GO:1900738","GO:2000707"]},{"accession":"XP_415080.3","go_terms":["GO:0006479","GO:0009236","GO:0006396","GO:0017000","GO:0035690","GO:0006656","GO:0019919","GO:0009102","GO:0030488","GO:0016049","GO:0018012","GO:0006744","GO:0010189","GO:0016126","GO:0043985","GO:0070476","GO:0046690","GO:0002098","GO:0000056","GO:0001300","GO:0090398","GO:0030961","GO:0006370","GO:0009877","GO:0042372","GO:0009234","GO:0009060","GO:0035573","GO:0035572","GO:0018013","GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:0031167","GO:0018364","GO:0036068","GO:0018026","GO:0018027","GO:0036265","GO:1901052","GO:0006364","GO:0000122","GO:0000154","GO:0046677","GO:0006400","GO:0071167","GO:0036261","GO:0009452","GO:0017126","GO:0006596"]},{"accession":"XP_003643500.4","go_terms":["GO:0000184","GO:1903259"]},{"accession":"XP_015155037.3","go_terms":["GO:0045451","GO:0000184","GO:0008103","GO:0007318","GO:0006397"]},{"accession":"NP_001264480.1","go_terms":["GO:1902172","GO:0060710","GO:0071385","GO:0038066","GO:0061470","GO:0003342","GO:0048382","GO:0048535","GO:0000288","GO:0045647","GO:0044344","GO:0002181","GO:0043029","GO:0046782","GO:0001782","GO:0098789","GO:2000766","GO:1900153","GO:0034247","GO:0045085","GO:1904246","GO:1904628","GO:0042129","GO:0061158","GO:0002635","GO:0031086","GO:0071364","GO:0045292","GO:0045657","GO:0097011","GO:1904582","GO:0097403","GO:0006378","GO:0006414","GO:0070371","GO:0071031","GO:0010587","GO:0019076","GO:0075713","GO:0019068","GO:0039702","GO:0000398","GO:0030260","GO:0039651","GO:0015074","GO:0000387","GO:0033120","GO:0045787","GO:0016567","GO:0007049"]},{"accession":"NP_001006151.2","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_015146530.1","go_terms":["GO:0042981","GO:0043392","GO:0016579"]},{"accession":"NP_001026464.2","go_terms":["GO:0042981","GO:0043392","GO:0016579"]}],"graph":[["NP_001264480.1","NP_001006151.2",0.746],["NP_001264480.1","NP_001026464.2",0.638],["NP_001264480.1","NP_001264651.1",0.767],["NP_001264480.1","XP_015146289.3",0.666],["NP_001264480.1","XP_015146530.1",0.674],["NP_001264480.1","XP_003643500.4",0.726],["NP_001264480.1","XP_015155037.3",0.599],["NP_001264480.1","XP_415080.3",0.758],["NP_001264480.1","XP_040561973.1",0.715],["NP_001006151.2","NP_001026464.2",0.635],["NP_001006151.2","NP_001264651.1",0.596],["NP_001006151.2","XP_003643500.4",0.697],["NP_001006151.2","XP_015146289.3",0.533],["NP_001006151.2","XP_015146530.1",0.619],["NP_001006151.2","XP_015155037.3",0.539],["NP_001006151.2","XP_040561973.1",0.569],["NP_001006151.2","XP_415080.3",0.744],["XP_040561973.1","XP_003643500.4",0.673],["XP_040561973.1","XP_015146289.3",0.684],["XP_040561973.1","XP_015146530.1",0.688],["XP_040561973.1","XP_015155037.3",0.686],["XP_040561973.1","XP_415080.3",0.842],["XP_040561973.1","NP_001026464.2",0.702],["XP_040561973.1","NP_001264651.1",0.729],["XP_003643500.4","XP_415080.3",0.545],["XP_003643500.4","NP_001026464.2",0.716],["XP_003643500.4","NP_001264651.1",0.535],["XP_003643500.4","XP_015146289.3",0.597],["XP_003643500.4","XP_015146530.1",0.693],["XP_003643500.4","XP_015155037.3",0.722],["XP_415080.3","XP_015146289.3",0.619],["XP_415080.3","XP_015146530.1",0.759],["XP_415080.3","XP_015155037.3",0.675],["XP_415080.3","NP_001026464.2",0.791],["XP_415080.3","NP_001264651.1",0.746],["NP_001026464.2","NP_001264651.1",0.757],["NP_001026464.2","XP_015146289.3",0.542],["NP_001026464.2","XP_015146530.1",0.696],["NP_001026464.2","XP_015155037.3",0.729],["XP_015155037.3","XP_015146289.3",0.559],["XP_015155037.3","XP_015146530.1",0.719],["XP_015155037.3","NP_001264651.1",0.609],["NP_001264651.1","XP_015146530.1",0.682],["XP_015146289.3","XP_015146530.1",0.565]],"all_go_terms":{"GO:0000245":1,"GO:0000387":2,"GO:0048025":3,"GO:0006376":3,"GO:0000380":3,"GO:0034462":3,"GO:0075522":3,"GO:1902625":3,"GO:0031047":3,"GO:0006378":4,"GO:0006446":3,"GO:1900363":3,"GO:0048255":3,"GO:0000381":3,"GO:0097010":3,"GO:0048026":3,"GO:0075525":3,"GO:0016556":3,"GO:1901407":3,"GO:0010610":3,"GO:0006406":3,"GO:0002188":3,"GO:0001825":3,"GO:0001731":3,"GO:1905663":3,"GO:0045292":4,"GO:1903586":3,"GO:0060211":3,"GO:0035278":3,"GO:1901899":1,"GO:0001525":1,"GO:0002551":1,"GO:0052338":1,"GO:0050829":1,"GO:1905183":1,"GO:0050930":1,"GO:0086030":1,"GO:0043303":1,"GO:2001237":1,"GO:2000707":1,"GO:2000352":1,"GO:0032762":1,"GO:0033604":1,"GO:1900738":1,"GO:0048245":1,"GO:0050830":1,"GO:0001938":1,"GO:0042372":1,"GO:0035690":1,"GO:0019919":1,"GO:0036265":1,"GO:0017000":1,"GO:0031167":1,"GO:0018026":1,"GO:0000056":1,"GO:0070476":1,"GO:0006479":1,"GO:0046690":1,"GO:0009234":1,"GO:0006596":1,"GO:0000122":1,"GO:0009236":1,"GO:0006400":1,"GO:0036261":1,"GO:0030488":1,"GO:0009102":1,"GO:0016049":1,"GO:0006370":1,"GO:0018012":1,"GO:0090398":1,"GO:0043985":1,"GO:0018027":1,"GO:0046677":1,"GO:1901052":1,"GO:0010189":1,"GO:0002098":1,"GO:0006744":1,"GO:0006656":1,"GO:0017126":1,"GO:0006396":1,"GO:0009452":1,"GO:0071167":1,"GO:0035573":1,"GO:0030961":1,"GO:0018364":1,"GO:0035572":1,"GO:0016126":1,"GO:0036068":1,"GO:0009060":1,"GO:0000154":1,"GO:0018013":1,"GO:0006364":1,"GO:0001300":1,"GO:0009877":1,"GO:1903259":1,"GO:0000184":2,"GO:0008103":1,"GO:0007318":1,"GO:0006397":1,"GO:0045451":1,"GO:0030260":1,"GO:0031086":1,"GO:0002181":1,"GO:1904582":1,"GO:0034247":1,"GO:1904246":1,"GO:1902172":1,"GO:0033120":1,"GO:0070371":1,"GO:0044344":1,"GO:0016567":1,"GO:0007049":1,"GO:0045085":1,"GO:0045647":1,"GO:0006414":1,"GO:0075713":1,"GO:0019068":1,"GO:2000766":1,"GO:0015074":1,"GO:0010587":1,"GO:0046782":1,"GO:0097011":1,"GO:0043029":1,"GO:1900153":1,"GO:0038066":1,"GO:0002635":1,"GO:0019076":1,"GO:0039702":1,"GO:0061158":1,"GO:0071385":1,"GO:0048382":1,"GO:0039651":1,"GO:0042129":1,"GO:0060710":1,"GO:0003342":1,"GO:1904628":1,"GO:0061470":1,"GO:0000398":1,"GO:0098789":1,"GO:0097403":1,"GO:0001782":1,"GO:0071364":1,"GO:0045787":1,"GO:0071031":1,"GO:0000288":1,"GO:0048535":1,"GO:0045657":1,"GO:0043392":2,"GO:0016579":2,"GO:0042981":2},"recipe_readded":[]}