{"hash":"259745798134868421","title":"DNA replication and repair with chromatin remodeling","description":"This cluster is dominated by terms related to DNA replication and various DNA repair pathways (including replication-born DSB repair and interstrand cross-link repair) and is complemented by chromatin-related activities such as heterochromatin formation and nucleosome dynamics. Transcription regulation terms are present but less central, suggesting the main theme is genome maintenance during replication with chromatin context. ","confidence":"Medium","size":13,"edges":78,"triangles":286,"max_degree":12,"top_function":"DNA replication","members":[{"accession":"NP_990561.2","go_terms":["GO:1903342","GO:0007076","GO:0000724","GO:0000733","GO:0070058","GO:0006260","GO:0009432","GO:0061780","GO:0007064","GO:0070550","GO:0010032","GO:0071960","GO:0051321","GO:0032876","GO:0098813","GO:0060821","GO:1990414"]},{"accession":"XP_004941764.1","go_terms":["GO:0006468","GO:0007623","GO:0000725","GO:0006355","GO:0070297","GO:0042754","GO:0006351","GO:0009649","GO:0000722","GO:2000269","GO:0071480","GO:0009636","GO:0051106","GO:0090267","GO:0036297","GO:0000732","GO:0007294","GO:0007066","GO:0007533","GO:0007141","GO:0010165","GO:0001541","GO:1990918","GO:0009949","GO:0051260","GO:0007129","GO:0000707","GO:0001556","GO:1990426","GO:0072757","GO:0000709","GO:0072719","GO:0010569","GO:0072711","GO:0007286","GO:0042148","GO:0007131","GO:0007130","GO:1904631","GO:0090656","GO:0009951","GO:0045003","GO:0006268","GO:0001832","GO:0030491","GO:0042493","GO:0030717","GO:1990414","GO:0001932","GO:0071140","GO:0016539","GO:0006260","GO:0006269","GO:0006276"]},{"accession":"XP_040504037.2","go_terms":["GO:0006295","GO:0006294","GO:0006296","GO:0006293","GO:0000717","GO:0070816","GO:0006363","GO:0006361","GO:0006370","GO:0006362","GO:0070911","GO:0006366"]},{"accession":"XP_046771875.1","go_terms":["GO:0030466","GO:0019731","GO:0031639","GO:0071169","GO:0008584","GO:0007296","GO:0035264","GO:0035023","GO:1904693","GO:0003344","GO:2000973","GO:0000122","GO:0034184","GO:0030543","GO:0002227","GO:0090230","GO:1902340","GO:0051290","GO:0007283","GO:0007338","GO:0007286","GO:0031509","GO:0006335","GO:0045618","GO:0042692","GO:0031508","GO:0000183","GO:1904815","GO:0061641","GO:0001649","GO:0071674","GO:0003209","GO:0045815","GO:0048477","GO:0033128","GO:0051572","GO:0070481","GO:0006997","GO:0007549","GO:0007420","GO:0035093","GO:0050830","GO:0061086","GO:1901837","GO:0061408","GO:0043966","GO:0000436","GO:0043457","GO:1900446","GO:2000306","GO:0042766","GO:0045898","GO:0008285","GO:0071392","GO:0043486","GO:0006334","GO:0006357"]},{"accession":"NP_001006243.1","go_terms":["GO:0006260","GO:0030163","GO:0030494","GO:0015979","GO:0030466","GO:0031939","GO:0030174","GO:0007307","GO:0007049","GO:0006348","GO:0000727","GO:0006343","GO:0072689","GO:0010082","GO:0006267","GO:0006268","GO:1902975","GO:1902450","GO:0090102","GO:0006279","GO:0006271","GO:1902969","GO:0071466","GO:0048478","GO:0031412","GO:0003341","GO:1990048","GO:0000027","GO:0042127","GO:0007292","GO:0042140"]},{"accession":"NP_001006527.3","go_terms":["GO:0006260","GO:0030163","GO:0030494","GO:0015979","GO:0030466","GO:0031939","GO:0030174","GO:0007307","GO:0007049","GO:0006348","GO:0000727","GO:0006343","GO:0072689","GO:0010082","GO:0006267","GO:0006268","GO:1902975","GO:1902450","GO:0090102","GO:0006279","GO:0006271","GO:1902969","GO:0071466","GO:0048478","GO:0042127","GO:0007292","GO:0042140"]},{"accession":"NP_001026065.1","go_terms":["GO:0061408","GO:0043966","GO:0000122","GO:0000436","GO:0043457","GO:1900446","GO:2000306","GO:0042766","GO:0045898","GO:0051123","GO:0006352","GO:0009736"]},{"accession":"NP_001034424.2","go_terms":["GO:1903342","GO:0007076","GO:0000724","GO:0000733","GO:0070058","GO:0006260","GO:0009432","GO:0061780","GO:0007064","GO:0070550","GO:0010032","GO:0071960"]},{"accession":"NP_001191861.1","go_terms":["GO:0034080","GO:0006335","GO:0000183","GO:0016233","GO:0051290","GO:0031047","GO:1904837","GO:0006303","GO:0045653","GO:0006352","GO:0045815","GO:0006312","GO:0051382","GO:0000712","GO:0036297","GO:0031297"]},{"accession":"NP_001264448.1","go_terms":["GO:0006295","GO:0006294","GO:0006296","GO:0006293","GO:0000717","GO:0070816","GO:0006363","GO:0006361","GO:0006370","GO:0006362","GO:0070911","GO:0006366"]},{"accession":"NP_001264524.1","go_terms":["GO:0006260","GO:0006281","GO:0071480","GO:0009636","GO:0051106","GO:0009432","GO:0010165","GO:0007127","GO:1990426","GO:0032508","GO:0072757","GO:0072719","GO:0072711","GO:0042148","GO:0007131","GO:1904631","GO:0045003","GO:0000730","GO:0000732","GO:1990414","GO:0001932","GO:0006412","GO:0071897"]},{"accession":"NP_001280098.2","go_terms":["GO:0006260","GO:0030163","GO:0030494","GO:0015979","GO:0030466","GO:0030174","GO:1902450","GO:0007307","GO:0007049","GO:0006279","GO:0006348","GO:0000727","GO:0006343","GO:0006271","GO:0072689","GO:0010082","GO:1902969","GO:0071466","GO:0006267","GO:0048478","GO:0031939","GO:0006268","GO:1902975","GO:0031412","GO:0003341","GO:1990048","GO:0000027","GO:0042127","GO:0007292","GO:0042140"]},{"accession":"NP_001289126.1","go_terms":["GO:0034080","GO:0051382","GO:0000712","GO:0036297","GO:0031398","GO:0031297","GO:0051301","GO:0000278","GO:0061408","GO:0043966","GO:0000122","GO:0000436","GO:0043457","GO:1900446","GO:2000306","GO:0042766","GO:0045898"]}],"graph":[["NP_001026065.1","NP_001006243.1",0.761],["NP_001026065.1","NP_001006527.3",0.768],["NP_001026065.1","NP_001034424.2",0.813],["NP_001026065.1","NP_001191861.1",0.761],["NP_001026065.1","NP_001264448.1",0.741],["NP_001026065.1","NP_001264524.1",0.781],["NP_001026065.1","NP_001280098.2",0.774],["NP_001026065.1","NP_001289126.1",0.709],["NP_001026065.1","NP_990561.2",0.825],["NP_001026065.1","XP_004941764.1",0.773],["NP_001026065.1","XP_040504037.2",0.713],["NP_001026065.1","XP_046771875.1",0.774],["NP_001006527.3","NP_001006243.1",0.73],["NP_001006527.3","NP_001280098.2",0.734],["NP_001006527.3","NP_001289126.1",0.755],["NP_001006527.3","NP_001264448.1",0.715],["NP_001006527.3","NP_001264524.1",0.744],["NP_001006527.3","NP_001191861.1",0.793],["NP_001006527.3","NP_001034424.2",0.775],["NP_001006527.3","XP_004941764.1",0.754],["NP_001006527.3","NP_990561.2",0.777],["NP_001006527.3","XP_040504037.2",0.708],["NP_001006527.3","XP_046771875.1",0.755],["NP_001191861.1","NP_001006243.1",0.727],["NP_001191861.1","NP_001034424.2",0.806],["NP_001191861.1","NP_001280098.2",0.765],["NP_001191861.1","NP_001289126.1",0.724],["NP_001191861.1","NP_001264448.1",0.741],["NP_001191861.1","NP_001264524.1",0.734],["NP_001191861.1","NP_990561.2",0.848],["NP_001191861.1","XP_004941764.1",0.788],["NP_001191861.1","XP_040504037.2",0.731],["NP_001191861.1","XP_046771875.1",0.723],["NP_001289126.1","NP_001006243.1",0.749],["NP_001289126.1","NP_001034424.2",0.835],["NP_001289126.1","NP_001264448.1",0.71],["NP_001289126.1","NP_001264524.1",0.748],["NP_001289126.1","NP_001280098.2",0.749],["NP_001289126.1","NP_990561.2",0.823],["NP_001289126.1","XP_004941764.1",0.756],["NP_001289126.1","XP_040504037.2",0.712],["NP_001289126.1","XP_046771875.1",0.71],["NP_990561.2","XP_046771875.1",0.833],["NP_990561.2","NP_001006243.1",0.787],["NP_990561.2","NP_001034424.2",0.503],["NP_990561.2","NP_001264448.1",0.77],["NP_990561.2","NP_001264524.1",0.8],["NP_990561.2","NP_001280098.2",0.794],["NP_990561.2","XP_004941764.1",0.754],["NP_990561.2","XP_040504037.2",0.769],["NP_001034424.2","NP_001006243.1",0.794],["NP_001034424.2","NP_001280098.2",0.778],["NP_001034424.2","NP_001264448.1",0.763],["NP_001034424.2","NP_001264524.1",0.803],["NP_001034424.2","XP_004941764.1",0.773],["NP_001034424.2","XP_040504037.2",0.76],["NP_001034424.2","XP_046771875.1",0.691],["NP_001006243.1","NP_001264448.1",0.754],["NP_001006243.1","NP_001264524.1",0.749],["NP_001006243.1","NP_001280098.2",0.737],["NP_001006243.1","XP_004941764.1",0.761],["NP_001006243.1","XP_040504037.2",0.734],["NP_001006243.1","XP_046771875.1",0.755],["NP_001280098.2","NP_001264448.1",0.719],["NP_001280098.2","NP_001264524.1",0.754],["NP_001280098.2","XP_004941764.1",0.749],["NP_001280098.2","XP_040504037.2",0.741],["NP_001280098.2","XP_046771875.1",0.749],["XP_004941764.1","XP_046771875.1",0.798],["XP_004941764.1","NP_001264448.1",0.733],["XP_004941764.1","NP_001264524.1",0.703],["XP_004941764.1","XP_040504037.2",0.729],["XP_040504037.2","XP_046771875.1",0.773],["XP_040504037.2","NP_001264448.1",0.55],["XP_040504037.2","NP_001264524.1",0.693],["XP_046771875.1","NP_001264448.1",0.769],["XP_046771875.1","NP_001264524.1",0.722],["NP_001264524.1","NP_001264448.1",0.715]],"all_go_terms":{"GO:0007064":2,"GO:0051321":1,"GO:0009432":3,"GO:1990414":3,"GO:0000733":2,"GO:0070058":2,"GO:1903342":2,"GO:0000724":2,"GO:0070550":2,"GO:0071960":2,"GO:0098813":1,"GO:0007076":2,"GO:0061780":2,"GO:0006260":7,"GO:0010032":2,"GO:0032876":1,"GO:0060821":1,"GO:0007131":2,"GO:0006351":1,"GO:0007533":1,"GO:0007129":1,"GO:0000725":1,"GO:0007623":1,"GO:1990426":2,"GO:0042493":1,"GO:0090656":1,"GO:0006268":4,"GO:0009951":1,"GO:0051260":1,"GO:0009636":2,"GO:0006355":1,"GO:0016539":1,"GO:0070297":1,"GO:0042148":2,"GO:0072711":2,"GO:0045003":2,"GO:0001932":2,"GO:0072719":2,"GO:0072757":2,"GO:0071480":2,"GO:0007286":2,"GO:0071140":1,"GO:0006269":1,"GO:0001541":1,"GO:0051106":2,"GO:0007066":1,"GO:0007294":1,"GO:0009949":1,"GO:0030717":1,"GO:0006276":1,"GO:0007130":1,"GO:0001832":1,"GO:0036297":3,"GO:0001556":1,"GO:0000722":1,"GO:0000709":1,"GO:0000732":2,"GO:0090267":1,"GO:0009649":1,"GO:0010165":2,"GO:2000269":1,"GO:0042754":1,"GO:0007141":1,"GO:0030491":1,"GO:1990918":1,"GO:0010569":1,"GO:0000707":1,"GO:0006468":1,"GO:1904631":2,"GO:0070911":2,"GO:0006363":2,"GO:0006295":2,"GO:0006370":2,"GO:0000717":2,"GO:0006294":2,"GO:0006362":2,"GO:0006366":2,"GO:0006361":2,"GO:0006296":2,"GO:0070816":2,"GO:0006293":2,"GO:0035093":1,"GO:0042766":3,"GO:0003209":1,"GO:0045815":2,"GO:0019731":1,"GO:0045898":3,"GO:0031639":1,"GO:0043486":1,"GO:0070481":1,"GO:0031508":1,"GO:0007549":1,"GO:0045618":1,"GO:0071392":1,"GO:0061641":1,"GO:2000973":1,"GO:0008285":1,"GO:0006335":2,"GO:0006357":1,"GO:0051572":1,"GO:0033128":1,"GO:0000122":3,"GO:1902340":1,"GO:0007338":1,"GO:0051290":2,"GO:0031509":1,"GO:1904693":1,"GO:0042692":1,"GO:1904815":1,"GO:1900446":3,"GO:0035264":1,"GO:0030466":4,"GO:2000306":3,"GO:0007420":1,"GO:0006997":1,"GO:1901837":1,"GO:0061408":3,"GO:0071169":1,"GO:0034184":1,"GO:0001649":1,"GO:0071674":1,"GO:0000183":2,"GO:0006334":1,"GO:0002227":1,"GO:0043966":3,"GO:0090230":1,"GO:0007296":1,"GO:0003344":1,"GO:0043457":3,"GO:0050830":1,"GO:0000436":3,"GO:0035023":1,"GO:0048477":1,"GO:0007283":1,"GO:0030543":1,"GO:0061086":1,"GO:0008584":1,"GO:1990048":2,"GO:0015979":3,"GO:0000027":2,"GO:0006271":3,"GO:1902975":3,"GO:0007292":3,"GO:0071466":3,"GO:0006343":3,"GO:0007049":3,"GO:0031412":2,"GO:0072689":3,"GO:0003341":2,"GO:0030494":3,"GO:0006279":3,"GO:0010082":3,"GO:0042127":3,"GO:0000727":3,"GO:0042140":3,"GO:0030163":3,"GO:1902969":3,"GO:0031939":3,"GO:0030174":3,"GO:0090102":2,"GO:0006348":3,"GO:1902450":3,"GO:0006267":3,"GO:0007307":3,"GO:0048478":3,"GO:0051123":1,"GO:0006352":2,"GO:0009736":1,"GO:0000712":2,"GO:0045653":1,"GO:0006303":1,"GO:0051382":2,"GO:0016233":1,"GO:0031297":2,"GO:1904837":1,"GO:0006312":1,"GO:0034080":2,"GO:0031047":1,"GO:0006412":1,"GO:0007127":1,"GO:0000730":1,"GO:0006281":1,"GO:0032508":1,"GO:0071897":1,"GO:0051301":1,"GO:0000278":1,"GO:0031398":1},"recipe_readded":[]}