{"hash":"2169185111665073513","title":"Golgi-ER and endosomal vesicle trafficking","description":"This cluster centers on vesicle trafficking pathways involving the Golgi and endosomal system, including retrograde transport between Golgi and ER, ER-to-Golgi and Golgi-to-ER transport, endocytosis, and Golgi localization/inheritance. It also includes synaptic vesicle budding, suggesting neuronal vesicle dynamics. The convergence of these GO terms supports a coherent function: management of vesicle trafficking and Golgi-endosome cycling, likely comprising proteins that regulate vesicle budding, cargo sorting, and Golgi maintenance. The presence of a few organismal-level terms may reflect broader context but do not undermine the core trafficking theme.","confidence":"High","size":9,"edges":36,"triangles":84,"max_degree":8,"top_function":null,"members":[{"accession":"XP_015154437.2","go_terms":["GO:0051123","GO:0010689","GO:1990141","GO:0010691","GO:0006351"]},{"accession":"XP_040513138.1","go_terms":["GO:0048313","GO:0006623","GO:0048490","GO:0042147","GO:0006888","GO:0051645","GO:1901998","GO:0006896","GO:0043473","GO:0006890","GO:0006897","GO:0016185","GO:0009615","GO:0008344","GO:0021691"]},{"accession":"XP_040562326.1","go_terms":["GO:0048313","GO:0006623","GO:0048490","GO:0042147","GO:0006888","GO:0051645","GO:1901998","GO:0006896","GO:0043473","GO:0006890","GO:0006897","GO:0016185","GO:0009615","GO:0008344","GO:0021691"]},{"accession":"NP_001006586.1","go_terms":["GO:0048313","GO:0006623","GO:0048490","GO:0042147","GO:0006888","GO:0051645","GO:1901998","GO:0006896","GO:0043473","GO:0006890","GO:0006897","GO:0016185","GO:0009615","GO:0008344","GO:0021691"]},{"accession":"NP_001278660.1","go_terms":["GO:0048313","GO:0006623","GO:0048490","GO:0042147","GO:0006888","GO:0051645","GO:1901998","GO:0006896","GO:0043473","GO:0006890","GO:0006897","GO:0016185","GO:0009615","GO:0008344","GO:0021691"]},{"accession":"XP_040558112.1","go_terms":["GO:0048313","GO:0006623","GO:0048490","GO:0042147","GO:0006888","GO:0051645","GO:1901998","GO:0006896","GO:0043473","GO:0006890","GO:0006897","GO:0016185","GO:0009615","GO:0008344","GO:0021691"]},{"accession":"NP_001107216.1","go_terms":["GO:0006903","GO:0034197","GO:0043308","GO:0006888","GO:0043320","GO:1990668","GO:0042144","GO:0042147","GO:0050775","GO:0006891","GO:0006890","GO:0043312","GO:0048280","GO:1903595","GO:0015031","GO:0035493","GO:1900483","GO:0032869","GO:0090161","GO:0043001","GO:0098967","GO:0016240","GO:0090316","GO:0001921","GO:0060291","GO:0016079","GO:1902259","GO:0043134","GO:0070254"]},{"accession":"XP_015127972.2","go_terms":["GO:0048280","GO:0032781","GO:0006886"]},{"accession":"XP_421226.3","go_terms":["GO:0048313","GO:0006623","GO:0048490","GO:0042147","GO:0006888","GO:0051645","GO:1901998","GO:0006896","GO:0043473","GO:0006890","GO:0006897","GO:0016185","GO:0009615","GO:0008344","GO:0021691"]}],"graph":[["XP_040562326.1","XP_015127972.2",0.715],["XP_040562326.1","XP_015154437.2",0.808],["XP_040562326.1","XP_040513138.1",0.742],["XP_040562326.1","XP_040558112.1",0.732],["XP_040562326.1","XP_421226.3",0.71],["XP_040562326.1","NP_001006586.1",0.743],["XP_040562326.1","NP_001107216.1",0.722],["XP_040562326.1","NP_001278660.1",0.736],["NP_001107216.1","NP_001006586.1",0.68],["NP_001107216.1","NP_001278660.1",0.702],["NP_001107216.1","XP_015127972.2",0.658],["NP_001107216.1","XP_015154437.2",0.765],["NP_001107216.1","XP_040513138.1",0.745],["NP_001107216.1","XP_040558112.1",0.68],["NP_001107216.1","XP_421226.3",0.724],["NP_001006586.1","NP_001278660.1",0.696],["NP_001006586.1","XP_015127972.2",0.7],["NP_001006586.1","XP_040513138.1",0.727],["NP_001006586.1","XP_015154437.2",0.772],["NP_001006586.1","XP_421226.3",0.714],["NP_001006586.1","XP_040558112.1",0.767],["XP_040558112.1","XP_015127972.2",0.75],["XP_040558112.1","XP_015154437.2",0.807],["XP_040558112.1","XP_040513138.1",0.666],["XP_040558112.1","XP_421226.3",0.65],["XP_040558112.1","NP_001278660.1",0.714],["XP_015127972.2","XP_015154437.2",0.786],["XP_015127972.2","XP_040513138.1",0.678],["XP_015127972.2","XP_421226.3",0.681],["XP_015127972.2","NP_001278660.1",0.689],["XP_421226.3","XP_015154437.2",0.844],["XP_421226.3","XP_040513138.1",0.703],["XP_421226.3","NP_001278660.1",0.707],["XP_040513138.1","XP_015154437.2",0.774],["XP_040513138.1","NP_001278660.1",0.735],["XP_015154437.2","NP_001278660.1",0.8]],"all_go_terms":{"GO:0051123":1,"GO:0006351":1,"GO:0010689":1,"GO:0010691":1,"GO:1990141":1,"GO:0006890":7,"GO:0009615":6,"GO:0016185":6,"GO:0008344":6,"GO:0006897":6,"GO:0042147":7,"GO:0051645":6,"GO:0006623":6,"GO:0048313":6,"GO:0021691":6,"GO:0048490":6,"GO:0043473":6,"GO:1901998":6,"GO:0006888":7,"GO:0006896":6,"GO:0043312":1,"GO:0006891":1,"GO:0006903":1,"GO:0001921":1,"GO:0048280":2,"GO:0042144":1,"GO:0032869":1,"GO:0050775":1,"GO:0035493":1,"GO:0070254":1,"GO:1903595":1,"GO:0090316":1,"GO:0043134":1,"GO:1902259":1,"GO:0034197":1,"GO:0016240":1,"GO:0090161":1,"GO:0060291":1,"GO:0016079":1,"GO:0043308":1,"GO:0015031":1,"GO:0043320":1,"GO:0043001":1,"GO:1900483":1,"GO:0098967":1,"GO:1990668":1,"GO:0032781":1,"GO:0006886":1},"recipe_readded":[]}