{"hash":"2101900024006989087","title":"Ribosome biogenesis and rRNA maturation","description":"This cluster is dominated by terms for translation, maturation of LSU- and SSU-rRNA, ribosome biogenesis, and snoRNP/snoRNA-associated RNA processing, indicating a core function in ribosome assembly and RNA modification/processing that supports translation. Some peripheral terms (splicing regulation, JNK signaling, selenocysteine incorporation) may reflect broader RNA metabolism or signaling links, but the central theme is ribosome production and rRNA maturation.","confidence":"High","size":19,"edges":170,"triangles":952,"max_degree":18,"top_function":"ribosome biogenesis","members":[{"accession":"NP_001006478.1","go_terms":["GO:0006614","GO:0006616"]},{"accession":"XP_046782516.1","go_terms":[]},{"accession":"NP_990439.1","go_terms":["GO:0045727","GO:0006412","GO:1902164","GO:1902167","GO:0032784","GO:0006977","GO:1904803","GO:0042273","GO:0031564","GO:0071480","GO:0006354","GO:0006353"]},{"accession":"NP_001264608.1","go_terms":["GO:0015968","GO:0006415","GO:0006412","GO:0000027"]},{"accession":"XP_001234052.1","go_terms":[]},{"accession":"XP_046797055.1","go_terms":["GO:0000470","GO:0006417","GO:0006412"]},{"accession":"NP_001001783.1","go_terms":["GO:0033119","GO:0000462","GO:0006417","GO:0006378","GO:0006412"]},{"accession":"NP_001006211.1","go_terms":["GO:0030595","GO:0001833","GO:0042254","GO:0007052","GO:0048539","GO:0042256","GO:0030282"]},{"accession":"NP_001007968.1","go_terms":["GO:0000185","GO:2000623","GO:0031118","GO:0031120","GO:0046330","GO:0007338","GO:0000470","GO:0048025","GO:0042254","GO:0001682","GO:1900745","GO:1904571","GO:0000492","GO:0006412"]},{"accession":"NP_001025790.1","go_terms":["GO:0042254","GO:0000028","GO:0000462","GO:0006412"]},{"accession":"NP_001075886.1","go_terms":["GO:0030154","GO:0043066","GO:0048477","GO:0006412"]},{"accession":"NP_001091005.1","go_terms":["GO:0045900","GO:0006614","GO:0006616"]},{"accession":"NP_001239073.1","go_terms":["GO:0000185","GO:2000623","GO:0031118","GO:0031120","GO:0046330","GO:0007338","GO:0000470","GO:0048025","GO:0042254","GO:0001682","GO:1900745","GO:1904571","GO:0000492","GO:0006412"]},{"accession":"NP_001244226.1","go_terms":["GO:2000032","GO:0090506","GO:0031581","GO:0000028","GO:0034198","GO:0006407"]},{"accession":"NP_001264840.1","go_terms":["GO:0000185","GO:2000623","GO:0031118","GO:0031120","GO:0046330","GO:0007338","GO:0000470","GO:0048025","GO:0042254","GO:0001682","GO:1900745","GO:1904571","GO:0000492","GO:0006412"]},{"accession":"NP_989548.1","go_terms":["GO:0034101","GO:0000028","GO:0006412"]},{"accession":"XP_418020.1","go_terms":["GO:0000470","GO:0006417","GO:0006412"]},{"accession":"XP_424029.4","go_terms":["GO:0007605"]},{"accession":"XP_428540.3","go_terms":["GO:0031564","GO:0000462","GO:0006412"]}],"graph":[["NP_001264840.1","NP_001001783.1",0.83],["NP_001264840.1","NP_001006211.1",0.831],["NP_001264840.1","NP_001006478.1",0.766],["NP_001264840.1","NP_001007968.1",0.843],["NP_001264840.1","NP_001025790.1",0.794],["NP_001264840.1","NP_001075886.1",0.807],["NP_001264840.1","NP_001091005.1",0.842],["NP_001264840.1","NP_001239073.1",0.798],["NP_001264840.1","NP_001244226.1",0.834],["NP_001264840.1","NP_001264608.1",0.817],["NP_001264840.1","NP_989548.1",0.782],["NP_001264840.1","XP_001234052.1",0.74],["NP_001264840.1","NP_990439.1",0.867],["NP_001264840.1","XP_428540.3",0.842],["NP_001264840.1","XP_424029.4",0.846],["NP_001264840.1","XP_418020.1",0.784],["NP_001264840.1","XP_046797055.1",0.812],["NP_001264840.1","XP_046782516.1",0.895],["NP_001239073.1","NP_001001783.1",0.723],["NP_001239073.1","NP_001006211.1",0.807],["NP_001239073.1","NP_001006478.1",0.854],["NP_001239073.1","NP_001007968.1",0.817],["NP_001239073.1","NP_001025790.1",0.716],["NP_001239073.1","NP_001075886.1",0.807],["NP_001239073.1","NP_001091005.1",0.84],["NP_001239073.1","NP_989548.1",0.79],["NP_001239073.1","NP_001244226.1",0.85],["NP_001239073.1","NP_001264608.1",0.838],["NP_001239073.1","NP_990439.1",0.821],["NP_001239073.1","XP_001234052.1",0.753],["NP_001239073.1","XP_046782516.1",0.811],["NP_001239073.1","XP_046797055.1",0.795],["NP_001239073.1","XP_418020.1",0.807],["NP_001239073.1","XP_424029.4",0.811],["NP_001239073.1","XP_428540.3",0.805],["NP_001001783.1","NP_001006211.1",0.833],["NP_001001783.1","NP_001006478.1",0.822],["NP_001001783.1","NP_001007968.1",0.8],["NP_001001783.1","NP_001025790.1",0.762],["NP_001001783.1","NP_001075886.1",0.842],["NP_001001783.1","NP_001091005.1",0.852],["NP_001001783.1","NP_001244226.1",0.798],["NP_001001783.1","NP_001264608.1",0.798],["NP_001001783.1","NP_989548.1",0.783],["NP_001001783.1","NP_990439.1",0.835],["NP_001001783.1","XP_001234052.1",0.778],["NP_001001783.1","XP_046782516.1",0.722],["NP_001001783.1","XP_046797055.1",0.727],["NP_001001783.1","XP_418020.1",0.853],["NP_001001783.1","XP_424029.4",0.815],["NP_001001783.1","XP_428540.3",0.816],["NP_001006211.1","NP_001006478.1",0.815],["NP_001006211.1","NP_001007968.1",0.818],["NP_001006211.1","NP_001025790.1",0.777],["NP_001006211.1","NP_001075886.1",0.785],["NP_001006211.1","NP_001091005.1",0.823],["NP_001006211.1","NP_001244226.1",0.779],["NP_001006211.1","NP_001264608.1",0.827],["NP_001006211.1","NP_989548.1",0.809],["NP_001006211.1","NP_990439.1",0.818],["NP_001006211.1","XP_001234052.1",0.827],["NP_001006211.1","XP_046782516.1",0.697],["NP_001006211.1","XP_046797055.1",0.816],["NP_001006211.1","XP_418020.1",0.794],["NP_001006211.1","XP_424029.4",0.768],["NP_001006211.1","XP_428540.3",0.801],["XP_046782516.1","NP_990439.1",0.781],["XP_046782516.1","XP_001234052.1",0.692],["XP_046782516.1","XP_428540.3",0.829],["XP_046782516.1","XP_424029.4",0.902],["XP_046782516.1","XP_418020.1",0.793],["XP_046782516.1","XP_046797055.1",0.768],["XP_046782516.1","NP_001006478.1",0.728],["XP_046782516.1","NP_001007968.1",0.824],["XP_046782516.1","NP_001025790.1",0.888],["XP_046782516.1","NP_001075886.1",0.707],["XP_046782516.1","NP_001091005.1",0.514],["XP_046782516.1","NP_001244226.1",0.778],["XP_046782516.1","NP_001264608.1",0.869],["XP_046782516.1","NP_989548.1",0.683],["NP_001025790.1","NP_001006478.1",0.826],["NP_001025790.1","NP_001007968.1",0.808],["NP_001025790.1","NP_001075886.1",0.822],["NP_001025790.1","NP_001091005.1",0.834],["NP_001025790.1","NP_001244226.1",0.811],["NP_001025790.1","NP_001264608.1",0.776],["NP_001025790.1","NP_989548.1",0.838],["NP_001025790.1","NP_990439.1",0.709],["NP_001025790.1","XP_001234052.1",0.854],["NP_001025790.1","XP_046797055.1",0.812],["NP_001025790.1","XP_418020.1",0.825],["NP_001025790.1","XP_424029.4",0.757],["NP_001025790.1","XP_428540.3",0.683],["NP_001244226.1","NP_001006478.1",0.861],["NP_001244226.1","NP_001007968.1",0.814],["NP_001244226.1","NP_001075886.1",0.787],["NP_001244226.1","NP_001091005.1",0.855],["NP_001244226.1","NP_989548.1",0.836],["NP_001244226.1","NP_001264608.1",0.82],["NP_001244226.1","NP_990439.1",0.761],["NP_001244226.1","XP_001234052.1",0.845],["NP_001244226.1","XP_046797055.1",0.753],["NP_001244226.1","XP_418020.1",0.86],["NP_001244226.1","XP_424029.4",0.79],["NP_001244226.1","XP_428540.3",0.743],["NP_989548.1","NP_001006478.1",0.817],["NP_989548.1","NP_001007968.1",0.778],["NP_989548.1","NP_001075886.1",0.807],["NP_989548.1","NP_001091005.1",0.838],["NP_989548.1","NP_001264608.1",0.859],["NP_989548.1","NP_990439.1",0.873],["NP_989548.1","XP_001234052.1",0.739],["NP_989548.1","XP_046797055.1",0.79],["NP_989548.1","XP_418020.1",0.85],["NP_989548.1","XP_424029.4",0.842],["NP_989548.1","XP_428540.3",0.788],["NP_001264608.1","NP_001006478.1",0.832],["NP_001264608.1","NP_001007968.1",0.824],["NP_001264608.1","NP_001075886.1",0.812],["NP_001264608.1","NP_001091005.1",0.791],["NP_001264608.1","XP_001234052.1",0.824],["NP_001264608.1","NP_990439.1",0.846],["NP_001264608.1","XP_428540.3",0.813],["NP_001264608.1","XP_424029.4",0.813],["NP_001264608.1","XP_418020.1",0.775],["NP_001264608.1","XP_046797055.1",0.787],["NP_001007968.1","NP_001006478.1",0.801],["NP_001007968.1","NP_001075886.1",0.783],["NP_001007968.1","NP_001091005.1",0.833],["NP_001007968.1","XP_001234052.1",0.77],["NP_001007968.1","NP_990439.1",0.817],["NP_001007968.1","XP_424029.4",0.787],["NP_001007968.1","XP_418020.1",0.744],["NP_001007968.1","XP_046797055.1",0.794],["XP_046797055.1","NP_990439.1",0.792],["XP_046797055.1","XP_001234052.1",0.808],["XP_046797055.1","XP_418020.1",0.774],["XP_046797055.1","XP_424029.4",0.797],["XP_046797055.1","XP_428540.3",0.793],["XP_046797055.1","NP_001006478.1",0.798],["XP_046797055.1","NP_001075886.1",0.759],["XP_046797055.1","NP_001091005.1",0.881],["NP_001091005.1","NP_001006478.1",0.785],["NP_001091005.1","NP_001075886.1",0.821],["NP_001091005.1","NP_990439.1",0.812],["NP_001091005.1","XP_001234052.1",0.844],["NP_001091005.1","XP_418020.1",0.828],["NP_001091005.1","XP_424029.4",0.649],["NP_001091005.1","XP_428540.3",0.783],["NP_001075886.1","NP_001006478.1",0.8],["NP_001075886.1","NP_990439.1",0.864],["NP_001075886.1","XP_001234052.1",0.817],["NP_001075886.1","XP_418020.1",0.818],["NP_001075886.1","XP_424029.4",0.847],["NP_001075886.1","XP_428540.3",0.809],["XP_001234052.1","XP_418020.1",0.718],["XP_001234052.1","XP_424029.4",0.868],["XP_001234052.1","XP_428540.3",0.823],["XP_001234052.1","NP_001006478.1",0.692],["XP_001234052.1","NP_990439.1",0.833],["XP_424029.4","NP_990439.1",0.772],["XP_424029.4","XP_418020.1",0.808],["XP_424029.4","XP_428540.3",0.745],["XP_424029.4","NP_001006478.1",0.797],["XP_418020.1","NP_990439.1",0.772],["XP_418020.1","XP_428540.3",0.808],["XP_418020.1","NP_001006478.1",0.83],["NP_001006478.1","NP_990439.1",0.799],["NP_001006478.1","XP_428540.3",0.758],["XP_428540.3","NP_990439.1",0.812]],"all_go_terms":{"GO:0006616":2,"GO:0006614":2,"GO:1902167":1,"GO:0006412":12,"GO:0032784":1,"GO:1902164":1,"GO:0042273":1,"GO:0006354":1,"GO:0031564":2,"GO:1904803":1,"GO:0006977":1,"GO:0006353":1,"GO:0071480":1,"GO:0045727":1,"GO:0000027":1,"GO:0015968":1,"GO:0006415":1,"GO:0006417":3,"GO:0000470":5,"GO:0006378":1,"GO:0033119":1,"GO:0000462":3,"GO:0048539":1,"GO:0007052":1,"GO:0030282":1,"GO:0042256":1,"GO:0030595":1,"GO:0001833":1,"GO:0042254":5,"GO:0031120":3,"GO:1904571":3,"GO:0048025":3,"GO:0046330":3,"GO:0000492":3,"GO:0007338":3,"GO:1900745":3,"GO:2000623":3,"GO:0031118":3,"GO:0001682":3,"GO:0000185":3,"GO:0000028":3,"GO:0043066":1,"GO:0048477":1,"GO:0030154":1,"GO:0045900":1,"GO:0031581":1,"GO:2000032":1,"GO:0034198":1,"GO:0090506":1,"GO:0006407":1,"GO:0034101":1,"GO:0007605":1},"recipe_readded":[]}