{"hash":"792227319849376492","title":"Oxidative Stress Response and Endocytosis","description":"The top GO terms center on oxidative stress and membrane trafficking: cellular response to hydrogen peroxide (GO:0070301), oxidation-reduction processes (GO:0055114), fatty acid response (GO:0071398), and endocytosis with regulation of phagocytosis (GO:0006897, GO:0050765). Together these point to a theme of managing stress signals at the plasma membrane and through endocytic pathways. The other terms (spermatid differentiation, neuron projection development, nucleotide biosynthesis) are more peripheral and do not form a single coherent functional axis, so the oxidative stress/trafficking theme best represents the cluster.","confidence":"Medium","size":15,"edges":92,"triangles":317,"max_degree":14,"top_function":null,"members":[{"accession":"XP_015992099.2","go_terms":["GO:0018106","GO:0045920","GO:0061508","GO:0002762","GO:0030819","GO:0006228","GO:0046777","GO:0048515","GO:0071333","GO:0045618","GO:0051259","GO:0071398","GO:0048550","GO:0070301","GO:0006241","GO:0050765","GO:0010976","GO:0006187","GO:0006186","GO:0006183","GO:0006897","GO:0007399","GO:0060416"]},{"accession":"XP_015992233.1","go_terms":["GO:0018106","GO:0045920","GO:0061508","GO:0002762","GO:0030819","GO:0006228","GO:0046777","GO:0048515","GO:0071333","GO:0045618","GO:0051259","GO:0071398","GO:0048550","GO:0070301","GO:0006241","GO:0050765","GO:0010976","GO:0006187","GO:0006186","GO:0006183","GO:0006897","GO:0007399","GO:0060416"]},{"accession":"XP_016014641.2","go_terms":["GO:0046039","GO:0044209","GO:0006270","GO:0046939","GO:0015951","GO:0001889","GO:0046041","GO:0046940","GO:0006172","GO:0007420","GO:0046705","GO:0015937","GO:0009435"]},{"accession":"XP_016016392.2","go_terms":["GO:1990355","GO:0070301","GO:0006464","GO:0055114","GO:0030091"]},{"accession":"XP_016016393.1","go_terms":["GO:1990355","GO:0070301","GO:0006464","GO:0055114","GO:0030091"]},{"accession":"XP_016021849.1","go_terms":["GO:0032543"]},{"accession":"XP_015976604.1","go_terms":["GO:2001213","GO:0007595","GO:0006124","GO:0009399","GO:0006814","GO:0045602","GO:1900747","GO:0009115","GO:0010124","GO:0042773"]},{"accession":"XP_015977721.2","go_terms":["GO:0018106","GO:0045920","GO:0061508","GO:0002762","GO:0030819","GO:0006228","GO:0046777","GO:0048515","GO:0071333","GO:0045618","GO:0051259","GO:0071398","GO:0048550","GO:0070301","GO:0006241","GO:0050765","GO:0010976","GO:0006187","GO:0006186","GO:0006183","GO:0006897","GO:0007399","GO:0060416"]},{"accession":"XP_015980217.2","go_terms":["GO:0006464","GO:0006979","GO:0055114","GO:0030091"]},{"accession":"XP_015983868.1","go_terms":["GO:0006099","GO:0009060","GO:0022904","GO:0044780","GO:0019516","GO:0006113","GO:0015948","GO:0071973","GO:0019684","GO:0055114"]},{"accession":"XP_015987289.1","go_terms":["GO:0042776","GO:0006122"]},{"accession":"XP_016010604.2","go_terms":["GO:0046381","GO:0042203","GO:1902600","GO:0010196","GO:0046232","GO:0015979","GO:0055114","GO:0006122"]},{"accession":"XP_016011397.1","go_terms":["GO:0003147","GO:0009263","GO:0098869","GO:0071473","GO:0030416","GO:0080058","GO:1903026","GO:0045454","GO:2000651","GO:0034599","GO:0055114"]},{"accession":"XP_036081131.1","go_terms":["GO:0006424","GO:0006425","GO:0006400","GO:0006412"]},{"accession":"XP_015978180.2","go_terms":["GO:0003147","GO:0009263","GO:0098869","GO:0071473","GO:0030416","GO:0080058","GO:1903026","GO:0045454","GO:2000651","GO:0034599","GO:0055114"]}],"graph":[["XP_016016393.1","XP_016010604.2",0.983],["XP_016016393.1","XP_016011397.1",0.95],["XP_016016393.1","XP_016014641.2",0.989],["XP_016016393.1","XP_016016392.2",0.97],["XP_016016393.1","XP_016021849.1",0.986],["XP_016016393.1","XP_036081131.1",0.97],["XP_016016393.1","XP_015976604.1",0.986],["XP_016016393.1","XP_015978180.2",0.966],["XP_016016393.1","XP_015980217.2",0.979],["XP_016016393.1","XP_015983868.1",0.97],["XP_016016393.1","XP_015992233.1",0.914],["XP_015978180.2","XP_015976604.1",0.967],["XP_015978180.2","XP_015977721.2",0.933],["XP_015978180.2","XP_015980217.2",0.956],["XP_015978180.2","XP_015983868.1",0.976],["XP_015978180.2","XP_015987289.1",0.877],["XP_015978180.2","XP_015992099.2",0.932],["XP_015978180.2","XP_015992233.1",0.975],["XP_015978180.2","XP_016010604.2",0.915],["XP_015978180.2","XP_016011397.1",0.964],["XP_015978180.2","XP_016014641.2",0.899],["XP_015978180.2","XP_016016392.2",0.98],["XP_015978180.2","XP_016021849.1",0.982],["XP_015978180.2","XP_036081131.1",0.964],["XP_036081131.1","XP_015992233.1",0.857],["XP_036081131.1","XP_016011397.1",0.973],["XP_036081131.1","XP_016014641.2",0.99],["XP_036081131.1","XP_016016392.2",0.984],["XP_036081131.1","XP_016021849.1",0.976],["XP_036081131.1","XP_015976604.1",0.982],["XP_036081131.1","XP_015977721.2",0.644],["XP_036081131.1","XP_015980217.2",0.987],["XP_036081131.1","XP_015983868.1",0.95],["XP_015980217.2","XP_015976604.1",0.972],["XP_015980217.2","XP_015977721.2",0.887],["XP_015980217.2","XP_015983868.1",0.989],["XP_015980217.2","XP_015987289.1",0.801],["XP_015980217.2","XP_015992099.2",0.971],["XP_015980217.2","XP_015992233.1",0.968],["XP_015980217.2","XP_016010604.2",0.726],["XP_015980217.2","XP_016011397.1",0.959],["XP_015980217.2","XP_016014641.2",0.983],["XP_015980217.2","XP_016016392.2",0.986],["XP_015980217.2","XP_016021849.1",0.984],["XP_015977721.2","XP_015976604.1",0.852],["XP_015977721.2","XP_015983868.1",0.937],["XP_015977721.2","XP_015987289.1",0.894],["XP_015977721.2","XP_015992099.2",0.812],["XP_015977721.2","XP_015992233.1",0.777],["XP_015977721.2","XP_016010604.2",0.775],["XP_015977721.2","XP_016011397.1",0.93],["XP_015977721.2","XP_016014641.2",0.842],["XP_015977721.2","XP_016021849.1",0.957],["XP_01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