{"hash":"2249827363639781318","title":"p53-Driven DNA Damage Response and Translation Regulation","description":"The terms cluster around ribosome biogenesis and translation (ribosomal subunit biogenesis, translation, cytosolic ribosome assembly, regulation of translation) and stress/damage signaling (cellular response to UV, cellular response to gamma radiation) tied to p53-mediated pathways (DNA damage response, transcription of p21, apoptotic signaling). This suggests a coherent module where DNA damage stress interfaces with control of protein synthesis and ribosome biogenesis, directed by p53. ","confidence":"High","size":6,"edges":1,"triangles":0,"max_degree":1,"top_function":null,"members":[{"accession":"XP_036083060.1","go_terms":["GO:0042273","GO:0071480","GO:1902167","GO:0042256","GO:0006977","GO:0034644","GO:0045727","GO:1902164","GO:0006412","GO:1904803"]},{"accession":"XP_016008498.2","go_terms":["GO:0042273","GO:0042274"]},{"accession":"XP_015998891.1","go_terms":["GO:0032435"]},{"accession":"XP_036090294.1","go_terms":["GO:0071549","GO:0006281","GO:0006412"]},{"accession":"XP_015981560.1","go_terms":["GO:0009239","GO:0036114","GO:0036116","GO:0045892","GO:0051792","GO:0035338","GO:0010124","GO:0045717","GO:1900535"]},{"accession":"XP_015993175.2","go_terms":["GO:0006729","GO:0006558","GO:0051289","GO:0051291","GO:0043496","GO:0006351","GO:0055114"]}],"graph":[["XP_036083060.1","XP_016008498.2",0.511]],"all_go_terms":{"GO:0006977":1,"GO:1902164":1,"GO:0034644":1,"GO:1904803":1,"GO:0042273":2,"GO:0006412":2,"GO:1902167":1,"GO:0045727":1,"GO:0071480":1,"GO:0042256":1,"GO:0042274":1,"GO:0032435":1,"GO:0006281":1,"GO:0071549":1,"GO:0010124":1,"GO:0035338":1,"GO:0036114":1,"GO:0009239":1,"GO:0045892":1,"GO:0045717":1,"GO:1900535":1,"GO:0051792":1,"GO:0036116":1,"GO:0006729":1,"GO:0043496":1,"GO:0051289":1,"GO:0006351":1,"GO:0055114":1,"GO:0051291":1,"GO:0006558":1},"recipe_readded":["XP_036074348.1","XP_036093757.1","XP_016008954.1","XP_015990900.1","XP_016008211.1","XP_016013628.1","XP_015993709.2","XP_036092551.1","XP_036091951.1","XP_015999021.2","XP_036090543.1","XP_015989464.2","XP_015978135.2","XP_016000456.1","XP_015995357.1","XP_016018089.1","XP_036082586.1","XP_015984082.1","XP_016019787.1","XP_015992803.2"]}