{"hash":"1164561873916894793","title":"Heart and vascular development with hypoxia signaling","description":"This cluster shows enrichment for cardiovascular-related GO terms: heart development, blood vessel diameter maintenance, oxygen transport, hypoxia response, and nitric oxide biosynthesis, plus platelet aggregation. The presence of oxidant detoxification and ECM/remodeling terms (negative regulation of collagen biosynthesis, fibroblast migration) also fits vascular development and remodeling. Together, these terms point to a coordinated heart and vascular development program with hypoxia and NO signaling involvement.","confidence":"High","size":15,"edges":35,"triangles":45,"max_degree":13,"top_function":null,"members":[{"accession":"XP_015991494.1","go_terms":["GO:0015701","GO:0030185","GO:0009399","GO:2000490","GO:0045429","GO:0042744","GO:0010942","GO:0001666","GO:0050880","GO:0043249","GO:0009636","GO:0098869","GO:0010764","GO:0007596","GO:0007507","GO:0051291","GO:0050873","GO:0051409","GO:0031444","GO:0042542","GO:0008217","GO:0006898","GO:0032966","GO:0043353","GO:0015671","GO:0070293","GO:0070527"]},{"accession":"XP_036082707.1","go_terms":["GO:0033214","GO:0048147","GO:0006880","GO:0030261","GO:0006950","GO:0097286","GO:1990461","GO:1904234","GO:0055114","GO:1904231"]},{"accession":"XP_036083157.1","go_terms":["GO:0033214","GO:0048147","GO:0006880","GO:0030261","GO:0006950","GO:0097286","GO:1990461","GO:1904234","GO:0055114","GO:1904231"]},{"accession":"XP_015977887.1","go_terms":["GO:0033214","GO:0048147","GO:0006880","GO:0030261","GO:0006950","GO:0097286","GO:1990461","GO:1904234","GO:0055114","GO:1904231"]},{"accession":"XP_015983414.1","go_terms":["GO:0033214","GO:0048147","GO:0006880","GO:0030261","GO:0006950","GO:0097286","GO:1990461","GO:1904234","GO:0055114","GO:1904231"]},{"accession":"XP_015991970.1","go_terms":["GO:0015701","GO:0030185","GO:0009399","GO:2000490","GO:0045429","GO:0042744","GO:0010942","GO:0001666","GO:0050880","GO:0043249","GO:0009636","GO:0098869","GO:0010764","GO:0007596","GO:0007507","GO:0051291","GO:0050873","GO:0051409","GO:0031444","GO:0042542","GO:0008217","GO:0006898","GO:0032966","GO:0043353","GO:0015671","GO:0070293","GO:0070527"]},{"accession":"XP_015991487.1","go_terms":["GO:0015701","GO:0030185","GO:0009399","GO:2000490","GO:0045429","GO:0042744","GO:0010942","GO:0001666","GO:0050880","GO:0043249","GO:0009636","GO:0098869","GO:0010764","GO:0007596","GO:0007507","GO:0051291","GO:0050873","GO:0051409","GO:0031444","GO:0042542","GO:0008217","GO:0006898","GO:0032966","GO:0043353","GO:0015671","GO:0070293","GO:0070527"]},{"accession":"XP_016019588.1","go_terms":[]},{"accession":"XP_036095362.1","go_terms":["GO:0008286","GO:0009736","GO:0090080","GO:0019762","GO:0019512","GO:0030245"]},{"accession":"XP_015998653.1","go_terms":["GO:0015701","GO:0030185","GO:0009399","GO:2000490","GO:0045429","GO:0042744","GO:0010942","GO:0001666","GO:0050880","GO:0043249","GO:0009636","GO:0098869","GO:0010764","GO:0007596","GO:0007507","GO:0051291","GO:0050873","GO:0051409","GO:0031444","GO:0042542","GO:0008217","GO:0006898","GO:0032966","GO:0043353","GO:0015671","GO:0070293","GO:0070527"]},{"accession":"XP_015990364.1","go_terms":["GO:0010248","GO:1903278","GO:0086036","GO:2000649","GO:0036376","GO:0090662","GO:1990573"]},{"accession":"XP_036085700.1","go_terms":[]},{"accession":"XP_016004080.1","go_terms":["GO:0035774","GO:1902361","GO:0061732"]},{"accession":"XP_036080587.1","go_terms":["GO:0007576","GO:0000122","GO:0046022","GO:0006351","GO:0070895","GO:0010729"]},{"accession":"XP_016009524.1","go_terms":["GO:0033327","GO:0032496","GO:0043085","GO:0098869","GO:0014070","GO:0019372","GO:0019370","GO:0008285","GO:0032526","GO:0070207","GO:0034097","GO:2001300","GO:0070268","GO:0071277","GO:0001516","GO:0002526","GO:0002540","GO:0002544","GO:0071449"]}],"graph":[["XP_036095362.1","XP_016004080.1",0.556],["XP_036095362.1","XP_016019588.1",0.615],["XP_036095362.1","XP_036085700.1",0.782],["XP_015990364.1","XP_015991970.1",0.5],["XP_016009524.1","XP_015991970.1",0.712],["XP_036083157.1","XP_015991487.1",0.749],["XP_036083157.1","XP_015991494.1",0.626],["XP_036083157.1","XP_015991970.1",0.745],["XP_036083157.1","XP_015998653.1",0.852],["XP_036083157.1","XP_036082707.1",0.803],["XP_036083157.1","XP_015977887.1",0.983],["XP_036083157.1","XP_015983414.1",0.734],["XP_016019588.1","XP_015991970.1",0.747],["XP_016004080.1","XP_015991970.1",0.562],["XP_036080587.1","XP_015991970.1",0.563],["XP_036082707.1","XP_015991487.1",0.925],["XP_036082707.1","XP_015991494.1",0.772],["XP_036082707.1","XP_015991970.1",0.781],["XP_036082707.1","XP_015998653.1",0.637],["XP_036082707.1","XP_015977887.1",0.955],["XP_036082707.1","XP_015983414.1",0.881],["XP_015983414.1","XP_015977887.1",0.776],["XP_015983414.1","XP_015998653.1",0.665],["XP_015983414.1","XP_015991487.1",0.668],["XP_015983414.1","XP_015991494.1",0.696],["XP_015983414.1","XP_015991970.1",0.713],["XP_015977887.1","XP_015991487.1",0.953],["XP_015977887.1","XP_015991494.1",0.909],["XP_015977887.1","XP_015991970.1",0.754],["XP_015977887.1","XP_015998653.1",0.637],["XP_036085700.1","XP_015991970.1",0.841],["XP_015991970.1","XP_015998653.1",0.539],["XP_015991970.1","XP_015991487.1",0.891],["XP_015991970.1","XP_015991494.1",0.812],["XP_015991487.1","XP_015991494.1",0.827]],"all_go_terms":{"GO:0042542":4,"GO:0098869":5,"GO:0032966":4,"GO:0010764":4,"GO:0050880":4,"GO:0015671":4,"GO:0001666":4,"GO:0045429":4,"GO:0007507":4,"GO:0070527":4,"GO:0050873":4,"GO:0051291":4,"GO:0010942":4,"GO:0015701":4,"GO:0043249":4,"GO:0008217":4,"GO:0009636":4,"GO:0006898":4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