{"hash":"2011045277902139104","title":"Ubiquitin-Dependent Immune Signaling and Stress Response","description":"The cluster is strongly associated with protein deubiquitination and immune signaling terms (T cell receptor signaling, MHC I antigen processing/presentation, TNF signaling, and regulation of inflammatory responses), suggesting a module where ubiquitin turnover modulates immune pathways. The presence of metal/ion stress responses (cadmium, zinc, salt) alongside these indicates broader stress-regulatory roles. Anaphase-promoting complex\u2013dependent catabolic process hints at protein turnover linked to cell cycle control, tying in ubiquitin-mediated regulation. Overall, a cohesive theme around ubiquitin-regulated immune signaling with stress response involvement.","confidence":"Medium","size":27,"edges":322,"triangles":2474,"max_degree":25,"top_function":null,"members":[{"accession":"XP_029203048.2","go_terms":["GO:1903061","GO:0061321","GO:0090083","GO:0032435","GO:0090367","GO:0071260","GO:0097192","GO:0010664","GO:0097201","GO:0008625","GO:0051496","GO:0010763","GO:1902176","GO:0031397","GO:2001145","GO:0010228","GO:0042993","GO:0071364","GO:0097178","GO:0046827","GO:0061084","GO:1903215"]},{"accession":"XP_029208136.1","go_terms":["GO:0090263","GO:0038061","GO:0033209","GO:0051437","GO:0051436","GO:0061418","GO:0080129","GO:0006521","GO:0002223","GO:0090090","GO:0050852","GO:0031146","GO:0031145","GO:0002862","GO:0010972","GO:0060071","GO:0010499","GO:0016032","GO:0010043","GO:0009651","GO:0043488","GO:0002479","GO:0046686","GO:0010950","GO:0038095","GO:0010363","GO:0016579"]},{"accession":"XP_029185038.1","go_terms":["GO:0090263","GO:0038061","GO:0033209","GO:0051437","GO:0051436","GO:0061418","GO:0080129","GO:0006521","GO:0002223","GO:0090090","GO:0050852","GO:0031146","GO:0031145","GO:0002862","GO:0010972","GO:0060071","GO:0010499","GO:0016032","GO:0010043","GO:0009651","GO:0043488","GO:0002479","GO:0046686","GO:0010950","GO:0038095","GO:0010363","GO:0016579"]},{"accession":"XP_029186584.1","go_terms":["GO:0090263","GO:0038061","GO:0033209","GO:0051437","GO:0051436","GO:0061418","GO:0080129","GO:0006521","GO:0002223","GO:0090090","GO:0050852","GO:0031146","GO:0031145","GO:0002862","GO:0010972","GO:0060071","GO:0010499","GO:0016032","GO:0010043","GO:0009651","GO:0043488","GO:0002479","GO:0046686","GO:0010950","GO:0038095","GO:0010363","GO:0016579"]},{"accession":"XP_029212856.2","go_terms":["GO:0048745","GO:0006616","GO:0071243","GO:0060324","GO:0003016","GO:0071218","GO:0010761","GO:0032436","GO:0070911","GO:0034126","GO:0090204","GO:0010286","GO:1901896","GO:0071276","GO:0043392","GO:0060334","GO:0051572","GO:0016925","GO:0043433","GO:0035186","GO:0086004","GO:0030578","GO:1902260","GO:0045944","GO:0045759","GO:0000423","GO:1901097","GO:0033132","GO:1902236","GO:1901340","GO:1903265","GO:0021888","GO:0014070","GO:0010216","GO:0045648","GO:0002109","GO:0006357","GO:0035973","GO:1901799","GO:1902283","GO:0016579","GO:1904378","GO:0030474","GO:0017085","GO:1903071","GO:0006289","GO:0051865","GO:0034140","GO:0030433","GO:1905366","GO:0000028","GO:0010636","GO:0010637","GO:0000753","GO:0071816","GO:0070842","GO:0097237","GO:1900186","GO:1904021","GO:0006517","GO:1904049","GO:0006412","GO:0007023","GO:0031117","GO:0014889","GO:0031122","GO:0048936"]},{"accession":"XP_029196658.1","go_terms":["GO:0090263","GO:0038061","GO:0033209","GO:0010043","GO:0009651","GO:0051437","GO:0051436","GO:0061418","GO:0080129","GO:0043488","GO:0006521","GO:0002479","GO:0046686","GO:0002223","GO:0090090","GO:0050852","GO:0031146","GO:0031145","GO:0060071","GO:0010972","GO:0010950","GO:0002862","GO:0038095","GO:0010363","GO:0016579","GO:0010499","GO:0016032"]},{"accession":"XP_044164411.1","go_terms":["GO:0019886","GO:0030473","GO:0035735","GO:0007290","GO:0007291","GO:0006888","GO:0007476","GO:0008407","GO:2000582","GO:0035721","GO:0035071","GO:0048477","GO:0044458","GO:0006351","GO:0034454","GO:0006914","GO:0006915","GO:0051017","GO:0008039","GO:0051292","GO:0007283","GO:0022416","GO:0022008","GO:1904801","GO:0035220","GO:0000132","GO:0006355","GO:1900740","GO:1902857"]},{"accession":"XP_029179764.2","go_terms":["GO:0090263","GO:0038061","GO:0033209","GO:0010043","GO:0009651","GO:0051437","GO:0051436","GO:0061418","GO:0080129","GO:0043488","GO:0006521","GO:0002479","GO:0046686","GO:0002223","GO:0090090","GO:0050852","GO:0031146","GO:0031145","GO:0060071","GO:0010972","GO:0010950","GO:0002862","GO:0038095","GO:0010363","GO:0016579","GO:0010499","GO:0016032"]},{"accession":"XP_029196754.2","go_terms":["GO:0060340","GO:1901097","GO:0006468","GO:1901340","GO:0035458","GO:0000226","GO:0030010","GO:0001828","GO:0001827","GO:1903094","GO:1904153","GO:2000157","GO:0010994","GO:0035973","GO:1904378","GO:0030474","GO:0032815","GO:1903071","GO:0006289","GO:0034140","GO:0035523","GO:0030433","GO:0035278","GO:0035329","GO:0044313","GO:1900186","GO:0070059","GO:0016567","GO:1904021","GO:0006517","GO:0000423","GO:0033132","GO:1902236","GO:1903265","GO:0021888","GO:0014070","GO:0010216","GO:0045648","GO:0002109","GO:0006357","GO:1901799","GO:1902283","GO:0016579","GO:0017085","GO:0051865","GO:0016925","GO:1905366","GO:0000028","GO:0010636","GO:0010637","GO:0000753","GO:0071816","GO:0070842","GO:0097237","GO:1904049","GO:0006412","GO:0015074","GO:0006508"]},{"accession":"XP_029212906.2","go_terms":["GO:0006284","GO:0097510"]},{"accession":"XP_044174106.1","go_terms":["GO:0000423","GO:1901097","GO:0033132","GO:1902236","GO:1901340","GO:1903265","GO:0021888","GO:0014070","GO:0010216","GO:0045648","GO:0002109","GO:0006357","GO:0035973","GO:1901799","GO:1902283","GO:0016579","GO:1904378","GO:0030474","GO:0017085","GO:1903071","GO:0006289","GO:0051865","GO:0034140","GO:0030433","GO:0016925","G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