{"hash":"505311685986439453","title":"RNA splicing, decay, and chromatin regulation","description":"The strongest signals are spliceosome-related processes (mRNA splicing, spliceosomal assembly) and mRNA turnover (P-body assembly, deadenylation-dependent decapping), plus rRNA maturation and transcription termination, pointing to a core RNA processing and gene expression regulation function. The presence of pericentric heterochromatin formation and hair cycle terms suggests additional chromatin-related regulation, but the dominant theme is RNA metabolism.","confidence":"Medium","size":16,"edges":120,"triangles":560,"max_degree":15,"top_function":null,"members":[{"accession":"XP_005146622.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_005141714.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_005147841.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_033928036.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_005142157.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_005146809.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:1903608","GO:0006396"]},{"accession":"XP_005148052.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_005149921.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_033917103.1","go_terms":["GO:0000492","GO:0051348","GO:0006986","GO:0000278","GO:0051301","GO:0072423","GO:1903220","GO:0000464","GO:0000354","GO:0034463","GO:0098789","GO:0006378","GO:0042868","GO:0007443","GO:0000245","GO:0007438","GO:0008380","GO:0006397"]},{"accession":"XP_033925319.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_033926390.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_033926406.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_033926793.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_033927084.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:1903608","GO:0006396"]},{"accession":"XP_033927462.1","go_terms":["GO:0034724","GO:0030574","GO:0034396","GO:0035551"]},{"accession":"XP_033928098.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]}],"graph":[["XP_033926793.1","XP_005141714.1",0.825],["XP_033926793.1","XP_005142157.1",0.883],["XP_033926793.1","XP_005146622.1",0.807],["XP_033926793.1","XP_005146809.1",0.955],["XP_033926793.1","XP_005147841.1",0.802],["XP_033926793.1","XP_005148052.1",0.829],["XP_033926793.1","XP_005149921.1",0.557],["XP_033926793.1","XP_033917103.1",0.957],["XP_033926793.1","XP_033925319.1",0.824],["XP_033926793.1","XP_033926390.1",0.704],["XP_033926793.1","XP_033926406.1",0.867],["XP_033926793.1","XP_033927084.1",0.866],["XP_033926793.1","XP_033927462.1",0.961],["XP_033926793.1","XP_033928036.1",0.868],["XP_033926793.1","XP_033928098.1",0.959],["XP_033925319.1","XP_005141714.1",0.765],["XP_033925319.1","XP_005142157.1",0.836],["XP_033925319.1","XP_005146622.1",0.721],["XP_033925319.1","XP_005146809.1",0.974],["XP_033925319.1","XP_005147841.1",0.805],["XP_033925319.1","XP_005148052.1",0.829],["XP_033925319.1","XP_005149921.1",0.637],["XP_033925319.1","XP_033917103.1",0.975],["XP_033925319.1","XP_033926390.1",0.782],["XP_033925319.1","XP_033926406.1",0.871],["XP_033925319.1","XP_033927084.1",0.902],["XP_033925319.1","XP_033927462.1",0.965],["XP_033925319.1","XP_033928036.1",0.797],["XP_033925319.1","XP_033928098.1",0.978],["XP_033917103.1","XP_005141714.1",0.979],["XP_033917103.1","XP_005142157.1",0.976],["XP_033917103.1","XP_005146622.1",0.974],["XP_033917103.1","XP_005146809.1",0.979],["XP_033917103.1","XP_005147841.1",0.947],["XP_033917103.1","XP_005148052.1",0.967],["XP_033917103.1","XP_005149921.1",0.941],["XP_033917103.1","XP_033926390.1",0.953],["XP_033917103.1","XP_033926406.1",0.968],["XP_033917103.1","XP_033927084.1",0.955],["XP_033917103.1","XP_033927462.1",0.892],["XP_033917103.1","XP_033928036.1",0.971],["XP_033917103.1","XP_033928098.1",0.985],["XP_033928098.1","XP_005141714.1",0.958],["XP_033928098.1","XP_005142157.1",0.954],["XP_033928098.1","XP_005146622.1",0.914],["XP_033928098.1","XP_005146809.1",0.986],["XP_033928098.1","XP_005147841.1",0.962],["XP_033928098.1","XP_005148052.1",0.961],["XP_033928098.1","XP_005149921.1",0.971],["XP_033928098.1","XP_033926390.1",0.969],["XP_033928098.1","XP_033926406.1",0.972],["XP_033928098.1","XP_033927084.1",0.971],["XP_033928098.1","XP_033927462.1",0.975],["XP_033928098.1","XP_033928036.1",0.96],["XP_005147841.1","XP_005141714.1",0.8],["XP_005147841.1","XP_005142157.1",0.75],["XP_005147841.1","XP_005146622.1",0.749],["XP_005147841.1","XP_005146809.1",0.973],["XP_005147841.1","XP_005148052.1",0.795],["XP_005147841.1","XP_005149921.1",0.666],["XP_005147841.1","XP_033926390.1",0.813],["XP_005147841.1","XP_033926406.1",0.789],["XP_005147841.1","XP_033927084.1",0.907],["XP_005147841.1","XP_033927462.1",0.955],["XP_005147841.1","XP_033928036.1",0.883],["XP_005146622.1","XP_005141714.1",0.81],["XP_005146622.1","XP_005142157.1",0.792],["XP_005146622.1","XP_005149921.1",0.543],["XP_005146622.1","XP_005148052.1",0.802],["XP_005146622.1","XP_005146809.1",0.907],["XP_005146622.1","XP_033928036.1",0.869],["XP_005146622.1","XP_033927084.1",0.909],["XP_005146622.1","XP_033927462.1",0.938],["XP_005146622.1","XP_033926390.1",0.64],["XP_005146622.1","XP_033926406.1",0.862],["XP_005141714.1","XP_005142157.1",0.804],["XP_005141714.1","XP_005146809.1",0.978],["XP_005141714.1","XP_005148052.1",0.834],["XP_005141714.1","XP_005149921.1",0.6],["XP_005141714.1","XP_033926390.1",0.754],["XP_005141714.1","XP_033926406.1",0.85],["XP_005141714.1","XP_033927084.1",0.908],["XP_005141714.1","XP_033927462.1",0.945],["XP_005141714.1","XP_033928036.1",0.886],["XP_033926406.1","XP_005142157.1",0.898],["XP_033926406.1","XP_005146809.1",0.949],["XP_033926406.1","XP_005148052.1",0.881],["XP_033926406.1","XP_005149921.1",0.85],["XP_033926406.1","XP_033928036.1",0.881],["XP_033926406.1","XP_033926390.1",0.851],["XP_033926406.1","XP_033927084.1",0.893],["XP_033926406.1","XP_033927462.1",0.92],["XP_033927462.1","XP_005142157.1",0.919],["XP_033927462.1","XP_005146809.1",0.955],["XP_033927462.1","XP_005148052.1",0.927],["XP_033927462.1","XP_005149921.1",0.941],["XP_033927462.1","XP_033926390.1",0.965],["XP_033927462.1","XP_033927084.1",0.954],["XP_033927462.1","XP_033928036.1",0.948],["XP_033927084.1","XP_005142157.1",0.9],["XP_033927084.1","XP_005146809.1",0.983],["XP_033927084.1","XP_005148052.1",0.932],["XP_033927084.1","XP_005149921.1",0.861],["XP_033927084.1","XP_033926390.1",0.846],["XP_033927084.1","XP_033928036.1",0.943],["XP_005142157.1","XP_005149921.1",0.605],["XP_005142157.1","XP_005148052.1",0.853],["XP_005142157.1","XP_005146809.1",0.96],["XP_005142157.1","XP_033928036.1",0.9],["XP_005142157.1","XP_033926390.1",0.724],["XP_005149921.1","XP_005146809.1",0.891],["XP_005149921.1","XP_005148052.1",0.615],["XP_005149921.1","XP_033928036.1",0.8],["XP_005149921.1","XP_033926390.1",0.584],["XP_033926390.1","XP_005146809.1",0.95],["XP_033926390.1","XP_005148052.1",0.717],["XP_033926390.1","XP_033928036.1",0.803],["XP_033928036.1","XP_005146809.1",0.967],["XP_033928036.1","XP_005148052.1",0.877],["XP_005146809.1","XP_005148052.1",0.934]],"all_go_terms":{"GO:1990141":12,"GO:0033962":12,"GO:0009737":12,"GO:0030490":12,"GO:0000290":12,"GO:0000387":12,"GO:0006369":12,"GO:0042633":12,"GO:0008033":12,"GO:0070317":12,"GO:0008334":12,"GO:0045292":14,"GO:0000245":13,"GO:0009414":12,"GO:0051170":12,"GO:0097010":2,"GO:0075525":2,"GO:0048025":2,"GO:0000380":2,"GO:1902625":2,"GO:0006406":2,"GO:0006396":2,"GO:0075522":2,"GO:0002188":2,"GO:0035278":2,"GO:1905663":2,"GO:0031047":2,"GO:1903608":2,"GO:0016556":2,"GO:0034462":2,"GO:0000381":2,"GO:0048255":2,"GO:0001825":2,"GO:1900363":2,"GO:1903586":2,"GO:0048026":2,"GO:0010610":2,"GO:0001731":2,"GO:1901407":2,"GO:0006378":3,"GO:0006376":2,"GO:0006446":2,"GO:0060211":2,"GO:0000354":1,"GO:0051301":1,"GO:1903220":1,"GO:0007443":1,"GO:0008380":1,"GO:0006397":1,"GO:0098789":1,"GO:0072423":1,"GO:0034463":1,"GO:0051348":1,"GO:0000464":1,"GO:0000492":1,"GO:0007438":1,"GO:0006986":1,"GO:0042868":1,"GO:0000278":1,"GO:0034396":1,"GO:0034724":1,"GO:0030574":1,"GO:0035551":1},"recipe_readded":[]}