{"hash":"198410096711536783","title":"Viral translation initiation and reinitiation","description":"This cluster is enriched for GO terms related to viral translation processes, including IRES-dependent initiation, translation reinitiation, and preinitiation complex formation, which together point to a shared function in initiating viral protein synthesis. Some terms about mRNA modification and ncRNA-mediated gene silencing appear as ancillary RNA processing links, but the dominant signal is translation initiation in a viral context.","confidence":"High","size":15,"edges":102,"triangles":419,"max_degree":14,"top_function":"regulatory ncRNA-mediated gene silencing","members":[{"accession":"XP_019793807.2","go_terms":[]},{"accession":"XP_019802780.2","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_019804063.2","go_terms":["GO:0000381","GO:0071347","GO:0006509","GO:0048025","GO:0048026","GO:0001649","GO:1905663","GO:1902625","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_033698122.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_033704878.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_073646731.1","go_terms":["GO:1902213","GO:0050775","GO:0009955","GO:0097150","GO:0048366","GO:1900170","GO:0016358","GO:0048013"]},{"accession":"XP_073660088.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_073663838.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_004311213.1","go_terms":["GO:1902213","GO:0050775","GO:0009955","GO:0097150","GO:0048366","GO:1900170","GO:0016358","GO:0048013"]},{"accession":"XP_004311214.1","go_terms":["GO:1902213","GO:0050775","GO:0009955","GO:0097150","GO:0048366","GO:1900170","GO:0016358","GO:0048013"]},{"accession":"XP_004313899.3","go_terms":["GO:0035774","GO:0031036","GO:0042554","GO:0007616","GO:0007614","GO:0051281","GO:0098735","GO:0010842","GO:0072286","GO:0060048","GO:0086004","GO:0072221","GO:0072205","GO:1901841","GO:1901844","GO:0055003","GO:0019749","GO:0099509","GO:0035502","GO:0006816","GO:0060315","GO:0051764","GO:0042994","GO:0000272","GO:0010459","GO:1900271","GO:0035191","GO:0042694","GO:1901077","GO:2000678","GO:0006470","GO:0036444","GO:0022011","GO:0021762","GO:1902527","GO:0014032","GO:0036324","GO:0014883","GO:0002027","GO:1903244","GO:1905205","GO:0051091","GO:0060316","GO:0035562","GO:0055117","GO:0050774","GO:0000754","GO:0014029","GO:0005513","GO:0045944","GO:0097274","GO:0010880","GO:0033234","GO:0032516","GO:1903799","GO:0070315","GO:0035690","GO:2001015","GO:0001525","GO:0051343","GO:0008218","GO:0001569","GO:0051561","GO:0032465","GO:0014718","GO:0099566","GO:0006919","GO:0048741","GO:0033555","GO:0071277","GO:0014044","GO:0060079","GO:0060487","GO:0007507","GO:0006491","GO:0030948","GO:0051531","GO:0051533","GO:0033173","GO:0014898","GO:0008365","GO:0048143","GO:0043950","GO:0042403","GO:0060040","GO:0051562","GO:0090281","GO:0007602","GO:0055010","GO:0043123","GO:0008284","GO:0032972","GO:0007601","GO:0006607","GO:0051591","GO:0051597","GO:0007409","GO:0007613","GO:0060291","GO:0070588","GO:0031284","GO:0051384","GO:0016237","GO:0051028","GO:0048168","GO:0030437","GO:0000278","GO:0050665","GO:0000742","GO:0045921","GO:0043065","GO:0046549","GO:0071456","GO:1901387","GO:0045917","GO:0006469","GO:0007020","GO:0008016","GO:0048708","GO:0008594","GO:1903525","GO:0042144","GO:0007269","GO:0048015","GO:0007114","GO:0048855","GO:1903087","GO:0001837","GO:0008360","GO:0032120","GO:0010515","GO:0006479","GO:0000086","GO:0038163","GO:0010801","GO:0051412","GO:1902896","GO:2000256","GO:0010800","GO:0007205","GO:0043647","GO:0010881","GO:0031954","GO:0043388","GO:0071902","GO:0043547","GO:1903479","GO:0007223","GO:0038095","GO:0045163","GO:0001975","GO:0005980","GO:0007190","GO:2000300","GO:0051000","GO:0070886","GO:0016061","GO:0071574","GO:1901339","GO:0022400","GO:0050906","GO:0002086","GO:0002576","GO:0009738","GO:1900242","GO:0006468","GO:0090151","GO:0086029","GO:0043931","GO:1901896","GO:0097050","GO:0007275","GO:0003220","GO:0003151","GO:0003073","GO:0098907","GO:0001824","GO:0071313","GO:0098904","GO:0043129","GO:0097264","GO:2001246","GO:0043588","GO:0007586","GO:0014808","GO:0036368","GO:0060056","GO:1901379","GO:0071872","GO:0007520","GO:0036151","GO:0016540","GO:0098910","GO:0014850"]},{"accession":"XP_004324496.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_019786037.1","go_terms":["GO:1902213","GO:0050775","GO:0009955","GO:0097150","GO:0048366","GO:1900170","GO:0016358","GO:0048013"]},{"accession":"XP_033710809.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_033693819.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:1903936","GO:0032212","GO:0032211","GO:1904579","GO:1990428","GO:1904577"]}],"graph":[["XP_004324496.1","XP_004311213.1",0.781],["XP_004324496.1","XP_004311214.1",0.798],["XP_004324496.1","XP_004313899.3",0.889],["XP_004324496.1","XP_019786037.1",0.824],["XP_004324496.1","XP_033698122.1",0.724],["XP_004324496.1","XP_019802780.2",0.888],["XP_004324496.1","XP_019804063.2",0.825],["XP_004324496.1","XP_019793807.2",0.881],["XP_004324496.1","XP_033710809.1",0.862],["XP_004324496.1","XP_033704878.1",0.863],["XP_004324496.1","XP_073663838.1",0.863],["XP_004324496.1","XP_073660088.1",0.897],["XP_004324496.1","XP_073646731.1",0.804],["XP_033704878.1","XP_019802780.2",0.916],["XP_033704878.1","XP_019804063.2",0.867],["XP_033704878.1","XP_033693819.1",0.733],["XP_033704878.1","XP_033698122.1",0.731],["XP_033704878.1","XP_033710809.1",0.857],["XP_033704878.1","XP_073663838.1",0.868],["XP_033704878.1","XP_073660088.1",0.923],["XP_033704878.1","XP_073646731.1",0.883],["XP_033704878.1","XP_004311213.1",0.867],["XP_033704878.1","XP_004311214.1",0.887],["XP_033704878.1","XP_004313899.3",0.863],["XP_033704878.1","XP_019786037.1",0.905],["XP_033704878.1","XP_019793807.2",0.877],["XP_004313899.3","XP_004311213.1",0.891],["XP_004313899.3","XP_004311214.1",0.91],["XP_004313899.3","XP_019786037.1",0.914],["XP_004313899.3","XP_019793807.2",0.887],["XP_004313899.3","XP_019802780.2",0.921],["XP_004313899.3","XP_019804063.2",0.849],["XP_004313899.3","XP_033698122.1",0.762],["XP_004313899.3","XP_033710809.1",0.922],["XP_004313899.3","XP_073646731.1",0.907],["XP_004313899.3","XP_073660088.1",0.912],["XP_004313899.3","XP_073663838.1",0.876],["XP_033698122.1","XP_033710809.1",0.748],["XP_033698122.1","XP_073646731.1",0.746],["XP_033698122.1","XP_073660088.1",0.903],["XP_033698122.1","XP_073663838.1",0.678],["XP_033698122.1","XP_004311213.1",0.738],["XP_033698122.1","XP_004311214.1",0.761],["XP_033698122.1","XP_019786037.1",0.725],["XP_033698122.1","XP_019793807.2",0.779],["XP_033698122.1","XP_019802780.2",0.772],["XP_033698122.1","XP_019804063.2",0.692],["XP_033698122.1","XP_033693819.1",0.672],["XP_004311214.1","XP_004311213.1",0.701],["XP_004311214.1","XP_019786037.1",0.635],["XP_004311214.1","XP_019793807.2",0.879],["XP_004311214.1","XP_019802780.2",0.924],["XP_004311214.1","XP_019804063.2",0.812],["XP_004311214.1","XP_033693819.1",0.743],["XP_004311214.1","XP_033710809.1",0.835],["XP_004311214.1","XP_073646731.1",0.659],["XP_004311214.1","XP_073660088.1",0.942],["XP_004311214.1","XP_073663838.1",0.864],["XP_073660088.1","XP_019793807.2",0.936],["XP_073660088.1","XP_019802780.2",0.931],["XP_073660088.1","XP_019804063.2",0.908],["XP_073660088.1","XP_033693819.1",0.828],["XP_073660088.1","XP_033710809.1",0.947],["XP_073660088.1","XP_073646731.1",0.93],["XP_073660088.1","XP_073663838.1",0.92],["XP_073660088.1","XP_004311213.1",0.942],["XP_073660088.1","XP_019786037.1",0.941],["XP_004311213.1","XP_019786037.1",0.646],["XP_004311213.1","XP_019793807.2",0.869],["XP_004311213.1","XP_019802780.2",0.919],["XP_004311213.1","XP_019804063.2",0.796],["XP_004311213.1","XP_033693819.1",0.717],["XP_004311213.1","XP_033710809.1",0.825],["XP_004311213.1","XP_073646731.1",0.689],["XP_004311213.1","XP_073663838.1",0.868],["XP_019804063.2","XP_033710809.1",0.864],["XP_019804063.2","XP_073646731.1",0.803],["XP_019804063.2","XP_073663838.1",0.873],["XP_019804063.2","XP_019786037.1",0.801],["XP_019804063.2","XP_019793807.2",0.852],["XP_019804063.2","XP_033693819.1",0.76],["XP_019804063.2","XP_019802780.2",0.897],["XP_019793807.2","XP_073646731.1",0.879],["XP_019793807.2","XP_073663838.1",0.869],["XP_019793807.2","XP_019786037.1",0.88],["XP_019793807.2","XP_019802780.2",0.913],["XP_019793807.2","XP_033710809.1",0.918],["XP_033710809.1","XP_019802780.2",0.861],["XP_033710809.1","XP_033693819.1",0.507],["XP_033710809.1","XP_073646731.1",0.834],["XP_033710809.1","XP_073663838.1",0.895],["XP_033710809.1","XP_019786037.1",0.821],["XP_019786037.1","XP_019802780.2",0.921],["XP_019786037.1","XP_033693819.1",0.638],["XP_019786037.1","XP_073646731.1",0.617],["XP_019786037.1","XP_073663838.1",0.854],["XP_033693819.1","XP_073646731.1",0.706],["XP_033693819.1","XP_073663838.1",0.539],["XP_033693819.1","XP_019802780.2",0.826],["XP_073646731.1","XP_019802780.2",0.928],["XP_073646731.1","XP_073663838.1",0.86],["XP_019802780.2","XP_073663838.1",0.913]],"all_go_terms":{"GO:0075525":9,"GO:1900363":9,"GO:0075522":9,"GO:0002188":9,"GO:0001731":9,"GO:0031047":9,"GO:1901407":9,"GO:0006378":9,"GO:0016556":9,"GO:1903586":9,"GO:0048025":9,"GO:0006376":9,"GO:0010610":9,"GO:0001825":9,"GO:0045292":9,"GO:0097010":9,"GO:0006406":9,"GO:0006446":9,"GO:0000380":9,"GO:0034462":9,"GO:0000381":9,"GO:0048255":9,"GO:0060211":9,"GO:0035278":9,"GO:1902625":9,"GO:1905663":9,"GO:0048026":9,"GO:0001649":1,"GO:0006509":1,"GO:0071347":1,"GO:1900170":4,"GO:1902213":4,"GO:0009955":4,"GO:0048013":4,"GO:0097150":4,"GO:0016358":4,"GO:0050775":4,"GO:0048366":4,"GO:0051343":1,"GO:0045944":1,"GO:0007114":1,"GO:0048015":1,"GO:1903479":1,"GO:0060315":1,"GO:0055010":1,"GO:0007586":1,"GO:0098735":1,"GO:0051384":1,"GO:2001015":1,"GO:0005513":1,"GO:0001525":1,"GO:0070588":1,"GO:0086029":1,"GO:1902527":1,"GO:0090281":1,"GO:0051764":1,"GO:0070886":1,"GO:0060056":1,"GO:0099566":1,"GO:0006468":1,"GO:0043123":1,"GO:0014850":1,"GO:0051562":1,"GO:0055003":1,"GO:0051281":1,"GO:0005980":1,"GO:0002086":1,"GO:1901379":1,"GO:1901077":1,"GO:0036151":1,"GO:0097050":1,"GO:0032972":1,"GO:0055117":1,"GO:0010459":1,"GO:2000678":1,"GO:0009738":1,"GO:0007190":1,"GO:0000278":1,"GO:0032465":1,"GO:0010881":1,"GO:0000086":1,"GO:0032516":1,"GO:0007613":1,"GO:0051597":1,"GO:1902896":1,"GO:0001569":1,"GO:0008016":1,"GO:0030437":1,"GO:0043647":1,"GO:0051561":1,"GO:0014718":1,"GO:0060487":1,"GO:0090151":1,"GO:0045921":1,"GO:0042554":1,"GO:0036368":1,"GO:0050665":1,"GO:0014898":1,"GO:0060048":1,"GO:0003151":1,"GO:0036324":1,"GO:0031036":1,"GO:0035690":1,"GO:1903087":1,"GO:0014808":1,"GO:0022011":1,"GO:0060079":1,"GO:0035191":1,"GO:0007205":1,"GO:0038095":1,"GO:0007020":1,"GO:0043065":1,"GO:1901339":1,"GO:0030948":1,"GO:0048168":1,"GO:0006491":1,"GO:0008594":1,"GO:0001837":1,"GO:0060316":1,"GO:0000754":1,"GO:0007275":1,"GO:0010515":1,"GO:0007616":1,"GO:0031284":1,"GO:0007614":1,"GO:0048143":1,"GO:1901387":1,"GO:0021762":1,"GO:1900271":1,"GO:0006479":1,"GO:0016061":1,"GO:0048741":1,"GO:0010842":1,"GO:0006607":1,"GO:0003220":1,"GO:0038163":1,"GO:0008365":1,"GO:0051000":1,"GO:0033234":1,"GO:0071872":1,"GO:0002576":1,"GO:2000300":1,"GO:2000256":1,"GO:0006816":1,"GO:0086004":1,"GO:0006470":1,"GO:0002027":1,"GO:0010801":1,"GO:0070315":1,"GO:0003073":1,"GO:0043931":1,"GO:1905205":1,"GO:0048708":1,"GO:0042694":1,"GO:0099509":1,"GO:0008218":1,"GO:0051533":1,"GO:0098904":1,"GO:0060291":1,"GO:0071574":1,"GO:0001975":1,"GO:1901896":1,"GO:1900242":1,"GO:1903244":1,"GO:0008284":1,"GO:0031954":1,"GO:0035502":1,"GO:0072221":1,"GO:0000272":1,"GO:0043547":1,"GO:2001246":1,"GO:0022400":1,"GO:0008360":1,"GO:0050906":1,"GO:0010880":1,"GO:0007223":1,"GO:0007507":1,"GO:0072205":1,"GO:0007409":1,"GO:0098910":1,"GO:0072286":1,"GO:0051028":1,"GO:0010800":1,"GO:0007520":1,"GO:1901844":1,"GO:0032120":1,"GO:0033555":1,"GO:0007602":1,"GO:0098907":1,"GO:0014044":1,"GO:1903525":1,"GO:0051591":1,"GO:0051091":1,"GO:0043129":1,"GO:0046549":1,"GO:0097264":1,"GO:0071277":1,"GO:0042403":1,"GO:0019749":1,"GO:0048855":1,"GO:0071456":1,"GO:0071313":1,"GO:1901841":1,"GO:0045917":1,"GO:0051412":1,"GO:0016237":1,"GO:0042144":1,"GO:0001824":1,"GO:0043950":1,"GO:0071902":1,"GO:0036444":1,"GO:1903799":1,"GO:0045163":1,"GO:0014029":1,"GO:0043388":1,"GO:0042994":1,"GO:0050774":1,"GO:0006919":1,"GO:0000742":1,"GO:0043588":1,"GO:0016540":1,"GO:0035774":1,"GO:0014032":1,"GO:0035562":1,"GO:0033173":1,"GO:0097274":1,"GO:0060040":1,"GO:0007269":1,"GO:0007601":1,"GO:0051531":1,"GO:0006469":1,"GO:0014883":1,"GO:1903936":1,"GO:0032212":1,"GO:1904577":1,"GO:1990428":1,"GO:0032211":1,"GO:1904579":1},"recipe_readded":[]}