{"hash":"2177434694436396902","title":"Ribosome Biogenesis and Translation Regulation","description":"The cluster is dominated by GO terms tied to ribosome production and protein synthesis: translation (GO:0006412), ribosomal large subunit biogenesis (GO:0042273), and ribosomal large subunit assembly (GO:0000027), plus positive regulation of translation (GO:0045727). While a few terms touch on transcription elongation and DNA damage\u2013related stress responses (p53-mediated pathways, gamma radiation response), these likely reflect broader cellular stress and transcription-translation coupling rather than defining the core function. Overall, the proteins appear to participate mainly in ribosome assembly and regulation of translation.","confidence":"High","size":7,"edges":21,"triangles":35,"max_degree":6,"top_function":null,"members":[{"accession":"NP_001003102.2","go_terms":["GO:1902164","GO:1902167","GO:0032784","GO:0006977","GO:1904803","GO:0042273","GO:0031564","GO:0071480","GO:0006354","GO:0006353","GO:0045727","GO:0006412"]},{"accession":"NP_001238885.1","go_terms":["GO:0015968","GO:0006415","GO:0006412","GO:0000027"]},{"accession":"NP_001300707.1","go_terms":["GO:0002181","GO:0000027"]},{"accession":"NP_001300711.1","go_terms":["GO:0042273","GO:0000055","GO:0006412"]},{"accession":"XP_038439281.1","go_terms":["GO:0006412"]},{"accession":"XP_038397379.1","go_terms":["GO:0034276","GO:0033512","GO:0042218","GO:0032869","GO:0000105","GO:0009102","GO:0019878","GO:0007219","GO:0006783","GO:0009862","GO:0019550","GO:0009236","GO:0006686","GO:0033585","GO:0015908","GO:0019441","GO:0006533","GO:0055089","GO:0006571","GO:0009835","GO:0019518","GO:0042853","GO:0097053","GO:0006523","GO:0006107","GO:0019551","GO:0006351","GO:0006532","GO:0006782","GO:0046511","GO:0033362"]},{"accession":"XP_038425452.1","go_terms":["GO:0006085","GO:0006099","GO:0006104"]}],"graph":[["NP_001300707.1","NP_001003102.2",0.736],["NP_001300707.1","NP_001238885.1",0.875],["NP_001300707.1","NP_001300711.1",0.922],["NP_001300707.1","XP_038397379.1",0.979],["NP_001300707.1","XP_038425452.1",0.943],["NP_001300707.1","XP_038439281.1",0.836],["NP_001300711.1","NP_001003102.2",0.845],["NP_001300711.1","NP_001238885.1",0.914],["NP_001300711.1","XP_038397379.1",0.987],["NP_001300711.1","XP_038425452.1",0.977],["NP_001300711.1","XP_038439281.1",0.944],["XP_038425452.1","XP_038439281.1",0.903],["XP_038425452.1","NP_001003102.2",0.832],["XP_038425452.1","NP_001238885.1",0.932],["XP_038425452.1","XP_038397379.1",0.986],["XP_038439281.1","XP_038397379.1",0.903],["XP_038439281.1","NP_001003102.2",0.91],["XP_038439281.1","NP_001238885.1",0.782],["XP_038397379.1","NP_001003102.2",0.979],["XP_038397379.1","NP_001238885.1",0.952],["NP_001238885.1","NP_001003102.2",0.754]],"all_go_terms":{"GO:1902167":1,"GO:0006977":1,"GO:0031564":1,"GO:0071480":1,"GO:0032784":1,"GO:0006412":4,"GO:0042273":2,"GO:0045727":1,"GO:0006354":1,"GO:1902164":1,"GO:1904803":1,"GO:0006353":1,"GO:0015968":1,"GO:0000027":2,"GO:0006415":1,"GO:0002181":1,"GO:0000055":1,"GO:0009102":1,"GO:0042853":1,"GO:0006107":1,"GO:0015908":1,"GO:0019441":1,"GO:0032869":1,"GO:0019518":1,"GO:0006351":1,"GO:0009862":1,"GO:0007219":1,"GO:0006686":1,"GO:0006533":1,"GO:0006532":1,"GO:0009835":1,"GO:0033362":1,"GO:0034276":1,"GO:0046511":1,"GO:0055089":1,"GO:0006571":1,"GO:0006783":1,"GO:0033512":1,"GO:0000105":1,"GO:0009236":1,"GO:0097053":1,"GO:0019551":1,"GO:0006523":1,"GO:0006782":1,"GO:0019550":1,"GO:0019878":1,"GO:0033585":1,"GO:0042218":1,"GO:0006099":1,"GO:0006085":1,"GO:0006104":1},"recipe_readded":[]}