{"hash":"554686841611730788","title":"Cellular redox detoxification and xenobiotic metabolism","description":"The cluster is driven by strong signals for redox balance and detoxification: GO:0098869 cellular oxidant detoxification, GO:0045454 cell redox homeostasis, and GO:0042178 xenobiotic catabolic process. Additional metabolism-related terms (methylamine metabolic process, regulation of nitrogen utilization) and calcium signaling (regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum) suggest a broader metabolic and signaling context, with some insulin-related regulation and a few incidental terms. Overall, the proteins appear to function together in detoxification and redox maintenance, with related metabolic modulation.","confidence":"Medium","size":21,"edges":156,"triangles":723,"max_degree":19,"top_function":null,"members":[{"accession":"XP_044556370.1","go_terms":["GO:0001949","GO:0032286","GO:0006636","GO:0000001","GO:0032443","GO:0006675","GO:0042128","GO:0006809"]},{"accession":"XP_044556502.1","go_terms":["GO:0051123","GO:0006283","GO:0031564","GO:0001172","GO:0032968","GO:0045899","GO:0001193","GO:0042797","GO:0031440","GO:0042254","GO:0006363","GO:0006362","GO:0006367","GO:0006366","GO:0006386","GO:0006379","GO:0042790"]},{"accession":"XP_044557104.1","go_terms":["GO:0051702","GO:0042311","GO:0033599","GO:0001885","GO:0009410","GO:0043403","GO:0009650","GO:0045444","GO:0051450","GO:0051897","GO:0010332","GO:0098869","GO:0007605","GO:0018158","GO:1902176","GO:0006641","GO:0048741","GO:0060055","GO:0002862","GO:0043534","GO:0001659","GO:0014902","GO:0008631","GO:0009609","GO:0033194","GO:0010269"]},{"accession":"XP_044557767.1","go_terms":["GO:0051726","GO:1902476","GO:0060315","GO:1902000","GO:0010880","GO:0051881","GO:0045669","GO:0070527","GO:0009072","GO:2001237","GO:0071222","GO:0033591","GO:0048147","GO:0009636","GO:0014003","GO:0071385","GO:0032869","GO:0043508","GO:0042178","GO:0007417","GO:0035726","GO:0032355","GO:1901687","GO:2000469","GO:0043651","GO:0070458","GO:0098869","GO:0070664","GO:2000429","GO:0043124","GO:0051771","GO:1904706","GO:0032720","GO:0019371","GO:0010804","GO:0006749","GO:0032930","GO:0014810","GO:0018916","GO:2000255","GO:0006289","GO:0045471","GO:0060316","GO:0031100","GO:0002674","GO:0071364","GO:0043200","GO:0001516","GO:0070373","GO:0032691","GO:1905804","GO:0071638","GO:0035732","GO:0071460","GO:0071672","GO:0019852","GO:0009407","GO:0042594","GO:0010731","GO:0045454","GO:0071243","GO:0010043","GO:0006808","GO:0042994","GO:0010044","GO:0009734","GO:0009635","GO:0002182","GO:0007608","GO:0055119","GO:0043517","GO:0071285","GO:2000774","GO:0060510","GO:0040008"]},{"accession":"XP_044558435.1","go_terms":["GO:0046381","GO:0042203","GO:1902600","GO:0010196","GO:0046232","GO:0015979","GO:0055114"]},{"accession":"XP_044558534.1","go_terms":["GO:0003147","GO:0009263","GO:0098869","GO:0071473","GO:0030416","GO:0080058","GO:1903026","GO:0045454","GO:2000651","GO:0034599","GO:0055114"]},{"accession":"XP_044558743.1","go_terms":["GO:0018106","GO:0045920","GO:0061508","GO:0002762","GO:0030819","GO:0006228","GO:0046777","GO:0048515","GO:0071333","GO:0045618","GO:0051259","GO:0071398","GO:0048550","GO:0070301","GO:0006241","GO:0050765","GO:0010976","GO:0006187","GO:0006186","GO:0006183","GO:0006897","GO:0007399","GO:0060416"]},{"accession":"XP_044559813.1","go_terms":["GO:0051123","GO:0006283","GO:0031564","GO:0001172","GO:0032968","GO:0045899","GO:0001193","GO:0042797","GO:0031440","GO:0042254","GO:0006363","GO:0006362","GO:0006367","GO:0006366","GO:0006386","GO:0006379","GO:0042790"]},{"accession":"XP_044562081.1","go_terms":["GO:0051702","GO:0042311","GO:0033599","GO:0001885","GO:0009410","GO:0043403","GO:0009650","GO:0045444","GO:0051450","GO:0051897","GO:0010332","GO:0098869","GO:0007605","GO:0018158","GO:1902176","GO:0006641","GO:0048741","GO:0060055","GO:0002862","GO:0043534","GO:0001659","GO:0014902","GO:0008631","GO:0009609","GO:0033194","GO:0010269"]},{"accession":"XP_044562173.1","go_terms":["GO:0010259","GO:0000422","GO:0043457"]},{"accession":"XP_044563793.1","go_terms":["GO:0051726","GO:1902476","GO:0060315","GO:1902000","GO:0010880","GO:0051881","GO:0045669","GO:0070527","GO:0009072","GO:0019852","GO:0009407","GO:0042594","GO:0014810","GO:0060316","GO:0006289","GO:0098869","GO:0010731","GO:0006749","GO:0045454","GO:0071243","GO:2001237","GO:0043508","GO:0033591","GO:0048147","GO:0002182","GO:0032930","GO:0018916","GO:0032869","GO:0006808","GO:0001516","GO:0051771","GO:0035726","GO:0043200","GO:0032355","GO:1901687","GO:0009734","GO:0042178","GO:0040008","GO:0002674","GO:0009636","GO:0043651","GO:0070458","GO:0032691","GO:0070664","GO:2000429","GO:0043124","GO:0007417","GO:1904706","GO:0032720","GO:0010804","GO:0007608","GO:0031100","GO:0071385","GO:2000469","GO:2000255","GO:0045471","GO:0014003","GO:0042994","GO:0071364","GO:0010044","GO:0071638","GO:0035732","GO:0071460","GO:0071672","GO:0070373","GO:0071285"]},{"accession":"XP_044563802.1","go_terms":["GO:0045454","GO:0043535","GO:0003147","GO:0009263","GO:0098869","GO:0071473","GO:0030416","GO:0080058","GO:1903026","GO:2000651","GO:0034599","GO:0055114"]},{"accession":"XP_044563899.1","go_terms":["GO:0046039","GO:0044209","GO:0006270","GO:0046939","GO:0015951","GO:0001889","GO:0046041","GO:0046940","GO:0006172","GO:0007420","GO:0046705"]},{"accession":"XP_044564077.1","go_terms":["GO:0018106","GO:0045920","GO:0061508","GO:0002762","GO:0030819","GO:0006228","GO:0046777","GO:0048515","GO:0071333","GO:0045618","GO:0051259","GO:0071398","GO:0048550","GO:0070301","GO:0006241","GO:0050765","GO:0010976","GO:0006187","GO:0006186","GO:0006183","GO:0006897","GO:0007399","GO:0060416"]},{"accession":"XP_044564953.1","go_terms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