{"hash":"1252875198686243262","title":"Apoptosis and Intracellular Signaling","description":"The terms point to stress- and signal-transduction-related processes, including apoptosis initiation (mitochondrial outer membrane permeabilization; extrinsic death receptor signaling), intracellular signaling cascades (cAMP/cGMP biosynthesis and forskolin response; general intracellular signal transduction), and related trafficking/localization (lysosome localization; synaptic vesicle transport). While diverse, the unifying theme is cellular signaling linked to cell fate decisions and stress responses, justifying a label centered on apoptosis and signaling.","confidence":"Medium","size":9,"edges":8,"triangles":0,"max_degree":8,"top_function":null,"members":[{"accession":"XP_044558143.1","go_terms":[]},{"accession":"XP_044565034.1","go_terms":["GO:0097345","GO:0008625","GO:0048490","GO:0032418"]},{"accession":"XP_044565770.1","go_terms":[]},{"accession":"XP_044567311.1","go_terms":[]},{"accession":"XP_044559051.1","go_terms":["GO:1904322","GO:0052565","GO:0009785","GO:0007168","GO:0035556","GO:0070483","GO:0006182","GO:1900194","GO:0030828","GO:0006355","GO:0001973","GO:0071880","GO:0006171"]},{"accession":"XP_044560341.1","go_terms":["GO:0006903","GO:0034197","GO:0043308","GO:0006888","GO:0043320","GO:1990668","GO:0042144","GO:0042147","GO:0050775","GO:0006891","GO:0006890","GO:0043312","GO:0048280","GO:1903595","GO:0015031","GO:0035493","GO:1900483","GO:0032869","GO:0090161","GO:0043001","GO:0098967","GO:0016240","GO:0090316","GO:0001921","GO:0060291","GO:0016079","GO:1902259","GO:0043134","GO:0070254"]},{"accession":"XP_044566757.1","go_terms":[]},{"accession":"XP_044561000.1","go_terms":[]},{"accession":"XP_044561987.1","go_terms":[]}],"graph":[["XP_044561000.1","XP_044566757.1",0.747],["XP_044561987.1","XP_044566757.1",0.774],["XP_044565034.1","XP_044566757.1",0.617],["XP_044567311.1","XP_044566757.1",0.608],["XP_044559051.1","XP_044566757.1",0.74],["XP_044565770.1","XP_044566757.1",0.581],["XP_044558143.1","XP_044566757.1",0.776],["XP_044566757.1","XP_044560341.1",0.787]],"all_go_terms":{"GO:0097345":1,"GO:0032418":1,"GO:0008625":1,"GO:0048490":1,"GO:0007168":1,"GO:0070483":1,"GO:0035556":1,"GO:0030828":1,"GO:0006171":1,"GO:1904322":1,"GO:0071880":1,"GO:0001973":1,"GO:0006182":1,"GO:0006355":1,"GO:0009785":1,"GO:1900194":1,"GO:0052565":1,"GO:0043320":1,"GO:0050775":1,"GO:0048280":1,"GO:0032869":1,"GO:0043312":1,"GO:0016240":1,"GO:0042144":1,"GO:0043001":1,"GO:0016079":1,"GO:1902259":1,"GO:1903595":1,"GO:0043308":1,"GO:0060291":1,"GO:0043134":1,"GO:0006888":1,"GO:1990668":1,"GO:0015031":1,"GO:0090161":1,"GO:0035493":1,"GO:0001921":1,"GO:0042147":1,"GO:0090316":1,"GO:0006890":1,"GO:0006903":1,"GO:0070254":1,"GO:0098967":1,"GO:0006891":1,"GO:1900483":1,"GO:0034197":1},"recipe_readded":[]}