{"hash":"128712110914670944","title":"Acetyl-CoA-driven central carbon metabolism","description":"This cluster is dominated by GO terms tied to acetyl-CoA production and core energy pathways: malonyl-CoA biosynthesis, pyruvate-to-acetyl-CoA formation, the TCA cycle, glycolysis, gluconeogenesis, and fatty acid biosynthesis, with several amino-acid catabolism routes funneling into acetyl-CoA. While a few terms touch on nucleotide metabolism or ion transport, the main signal is central carbon metabolism centered on acetyl-CoA flux.","confidence":"High","size":9,"edges":36,"triangles":84,"max_degree":8,"top_function":null,"members":[{"accession":"XP_067815158.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]},{"accession":"XP_067814925.1","go_terms":["GO:0033512","GO:0006814","GO:0006099","GO:2001295","GO:0042759","GO:0006096","GO:0006086","GO:0006552","GO:0006213","GO:0006094"]},{"accession":"XP_067815133.1","go_terms":["GO:0033512","GO:0006814","GO:0006099","GO:2001295","GO:0042759","GO:0006096","GO:0006086","GO:0006552","GO:0006213","GO:0006094"]},{"accession":"XP_067818338.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]},{"accession":"XP_067818999.1","go_terms":["GO:0009249","GO:0019464"]},{"accession":"XP_067823186.1","go_terms":["GO:0043617","GO:0006086","GO:0000002","GO:0006099","GO:0006103","GO:0033512","GO:0006096","GO:0006814","GO:2001295","GO:0042759","GO:0006552","GO:0006213","GO:0006094"]},{"accession":"XP_067815953.1","go_terms":["GO:0033512","GO:0006814","GO:0006099","GO:2001295","GO:0042759","GO:0006096","GO:0006086","GO:0006552","GO:0006213","GO:0006094"]},{"accession":"XP_067815018.1","go_terms":["GO:0033512","GO:0006814","GO:0006099","GO:2001295","GO:0042759","GO:0006096","GO:0006086","GO:0006552","GO:0006213","GO:0006094"]},{"accession":"XP_067821590.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]}],"graph":[["XP_067815018.1","XP_067818999.1",0.97],["XP_067815018.1","XP_067818338.1",0.984],["XP_067815018.1","XP_067815953.1",0.981],["XP_067815018.1","XP_067814925.1",0.989],["XP_067815018.1","XP_067815133.1",0.986],["XP_067815018.1","XP_067815158.1",0.988],["XP_067815018.1","XP_067823186.1",0.99],["XP_067815018.1","XP_067821590.1",0.986],["XP_067814925.1","XP_067818999.1",0.979],["XP_067814925.1","XP_067818338.1",0.982],["XP_067814925.1","XP_067815953.1",0.989],["XP_067814925.1","XP_067815133.1",0.99],["XP_067814925.1","XP_067815158.1",0.988],["XP_067814925.1","XP_067823186.1",0.988],["XP_067814925.1","XP_067821590.1",0.985],["XP_067818999.1","XP_067815133.1",0.966],["XP_067818999.1","XP_067815158.1",0.976],["XP_067818999.1","XP_067815953.1",0.976],["XP_067818999.1","XP_067818338.1",0.968],["XP_067818999.1","XP_067821590.1",0.975],["XP_067818999.1","XP_067823186.1",0.959],["XP_067823186.1","XP_067815133.1",0.991],["XP_067823186.1","XP_067815158.1",0.988],["XP_067823186.1","XP_067815953.1",0.992],["XP_067823186.1","XP_067818338.1",0.977],["XP_067823186.1","XP_067821590.1",0.986],["XP_067818338.1","XP_067815133.1",0.985],["XP_067818338.1","XP_067815158.1",0.988],["XP_067818338.1","XP_067815953.1",0.977],["XP_067818338.1","XP_067821590.1",0.987],["XP_067815133.1","XP_067815953.1",0.983],["XP_067815133.1","XP_067815158.1",0.984],["XP_067815133.1","XP_067821590.1",0.986],["XP_067815953.1","XP_067815158.1",0.985],["XP_067815953.1","XP_067821590.1",0.983],["XP_067815158.1","XP_067821590.1",0.988]],"all_go_terms":{"GO:0009234":3,"GO:0017000":3,"GO:0006635":3,"GO:0006574":3,"GO:0042372":3,"GO:0010124":3,"GO:2001295":5,"GO:0006086":5,"GO:0006099":5,"GO:0006213":5,"GO:0006814":5,"GO:0006096":5,"GO:0042759":5,"GO:0033512":5,"GO:0006552":5,"GO:0006094":5,"GO:0009249":1,"GO:0019464":1,"GO:0006103":1,"GO:0043617":1,"GO:0000002":1},"recipe_readded":[]}