{"hash":"663164903781035396","title":"Bacterial amino acid and cofactor biosynthesis","description":"This cluster centers on multiple biosynthetic processes in bacteria, including amino acids (serine, proline, lysine), cofactors (biotin), and heme precursors (protoporphyrinogen IX), with additional signals of antibiotic and lipopolysaccharide biosynthesis. The shared theme is diverse bacterial biosynthetic activities rather than a single defined pathway, supporting a general biosynthesis label.","confidence":"Medium","size":12,"edges":64,"triangles":200,"max_degree":11,"top_function":"carbohydrate metabolic process","members":[{"accession":"XP_001515596.2","go_terms":["GO:0019595","GO:0051160","GO:0003016","GO:0042572","GO:0032496","GO:0042573","GO:0009809","GO:0033859","GO:0000947","GO:0006116","GO:0046688","GO:1900116","GO:0033498","GO:0018119","GO:0046370","GO:0051409","GO:0019518","GO:0045777","GO:0043458","GO:0046294","GO:1901159","GO:0006062","GO:0010430","GO:0006068","GO:0006069","GO:0006633","GO:0006693","GO:0097327","GO:0055114"]},{"accession":"XP_028902313.1","go_terms":["GO:0006085","GO:0006099","GO:0006104","GO:0006351","GO:0045892","GO:0051775"]},{"accession":"XP_028916060.1","go_terms":["GO:0019491","GO:0048148","GO:0017000","GO:0009450","GO:0009413","GO:0055129","GO:0009102","GO:0019878","GO:0015995","GO:0006782","GO:0006593","GO:0010121","GO:0009447","GO:0019481","GO:0019483","GO:0042450","GO:0009089"]},{"accession":"XP_028917855.1","go_terms":["GO:0034276","GO:0033512","GO:0042218","GO:0032869","GO:0000105","GO:0009102","GO:0019878","GO:0007219","GO:0006783","GO:0009862","GO:0019550","GO:0009236","GO:0006686","GO:0033585","GO:0015908","GO:0019441","GO:0006533","GO:0055089","GO:0006571","GO:0009835","GO:0019518","GO:0042853","GO:0097053","GO:0006523","GO:0006107","GO:0019551","GO:0006351","GO:0006532","GO:0006782","GO:0046511","GO:0033362","GO:0009243","GO:0017000","GO:0009246","GO:0009245","GO:0071555","GO:0046677","GO:0009103"]},{"accession":"XP_028921608.1","go_terms":["GO:0033539","GO:0009437"]},{"accession":"XP_039767430.1","go_terms":["GO:0019491","GO:0048148","GO:0017000","GO:0009450","GO:0009413","GO:0055129","GO:0009102","GO:0019878","GO:0015995","GO:0006782","GO:0006593","GO:0010121","GO:0009447","GO:0019481","GO:0019483","GO:0042450","GO:0009089"]},{"accession":"XP_007654785.1","go_terms":["GO:1904482","GO:0034340","GO:0035999","GO:0009113","GO:0046655","GO:0006565","GO:0006564","GO:0006231","GO:0051289","GO:0019264","GO:0017148","GO:0032259"]},{"accession":"XP_001505830.1","go_terms":["GO:0030836","GO:0016311","GO:0032361","GO:0009244","GO:0071318","GO:0097171","GO:0031247","GO:0009103","GO:0033574","GO:0006564","GO:0097755","GO:0006874","GO:0070574","GO:0071577","GO:0006825","GO:0046839","GO:0019373","GO:0046272","GO:0046196","GO:0006470","GO:0046050","GO:0006114","GO:0046380","GO:0005975","GO:0046295","GO:0006045","GO:0019700"]},{"accession":"XP_028914477.1","go_terms":["GO:0030836","GO:0016311","GO:0032361","GO:0009244","GO:0071318","GO:0097171","GO:0031247","GO:0009103","GO:0033574","GO:0006564","GO:0097755","GO:0006874","GO:0070574","GO:0071577","GO:0006825","GO:0046839","GO:0019373","GO:0046272","GO:0046196","GO:0006470","GO:0046050","GO:0006114","GO:0046380","GO:0005975","GO:0046295","GO:0006045","GO:0019700"]},{"accession":"XP_028916712.1","go_terms":["GO:0007494","GO:0048566","GO:0031016","GO:0031076","GO:0009450","GO:0060324","GO:0021983","GO:0021915","GO:0042572","GO:0042574","GO:0048384","GO:0021768","GO:0035799","GO:0014032","GO:0050885","GO:0009258","GO:0001568","GO:0006540","GO:0042904","GO:0043584","GO:0019545","GO:0019544","GO:1901023","GO:0009954","GO:0019285","GO:0007584","GO:0060013","GO:0070384","GO:0060166","GO:0009447","GO:0003007","GO:0035115","GO:0051591","GO:0010133","GO:0006678","GO:0042472","GO:0009952","GO:0002072","GO:0019413","GO:0036293","GO:0055129","GO:0015976","GO:0032180","GO:0048738","GO:0071300","GO:0006537","GO:0030900","GO:0030902","GO:0009855","GO:0001936","GO:0006068","GO:0006069","GO:0044210","GO:0006526","GO:0046939","GO:0035975","GO:0009089","GO:0019877","GO:0019546","GO:0009090","GO:0009088"]},{"accession":"XP_028925844.1","go_terms":["GO:0019367","GO:0051790","GO:0017000","GO:0051792"]},{"accession":"XP_028917201.1","go_terms":["GO:0030836","GO:0016311","GO:0032361","GO:0009244","GO:0071318","GO:0097171","GO:0031247","GO:0009103","GO:0033574","GO:0006564","GO:0097755","GO:0006874","GO:0070574","GO:0071577","GO:0006825","GO:0046839","GO:0019373","GO:0046272","GO:0046196","GO:0006470","GO:0046050","GO:0006114","GO:0046380","GO:0005975","GO:0046295","GO:0006045","GO:0019700"]}],"graph":[["XP_001505830.1","XP_001515596.2",0.933],["XP_001505830.1","XP_007654785.1",0.757],["XP_001505830.1","XP_028902313.1",0.53],["XP_001505830.1","XP_028914477.1",0.594],["XP_001505830.1","XP_028916060.1",0.856],["XP_001505830.1","XP_028916712.1",0.91],["XP_001505830.1","XP_028917201.1",0.905],["XP_001505830.1","XP_028917855.1",0.797],["XP_001505830.1","XP_028921608.1",0.904],["XP_001505830.1","XP_028925844.1",0.909],["XP_001505830.1","XP_039767430.1",0.707],["XP_039767430.1","XP_001515596.2",0.591],["XP_039767430.1","XP_007654785.1",0.936],["XP_039767430.1","XP_028902313.1",0.808],["XP_039767430.1","XP_028914477.1",0.802],["XP_039767430.1","XP_028916060.1",0.702],["XP_039767430.1","XP_028916712.1",0.764],["XP_039767430.1","XP_028917201.1",0.837],["XP_039767430.1","XP_028917855.1",0.622],["XP_039767430.1","XP_028925844.1",0.887],["XP_028916060.1","XP_001515596.2",0.867],["XP_028916060.1","XP_007654785.1",0.928],["XP_028916060.1","XP_028902313.1",0.824],["XP_028916060.1","XP_028914477.1",0.923],["XP_028916060.1","XP_028916712.1",0.775],["XP_028916060.1","XP_028917201.1",0.852],["XP_028916060.1","XP_028917855.1",0.901],["XP_028916060.1","XP_028921608.1",0.743],["XP_028916060.1","XP_028925844.1",0.925],["XP_007654785.1","XP_001515596.2",0.783],["XP_007654785.1","XP_028902313.1",0.941],["XP_007654785.1","XP_028925844.1",0.966],["XP_007654785.1","XP_028921608.1",0.637],["XP_007654785.1","XP_028917855.1",0.965],["XP_007654785.1","XP_028916712.1",0.836],["XP_007654785.1","XP_028917201.1",0.72],["XP_007654785.1","XP_028914477.1",0.909],["XP_028902313.1","XP_001515596.2",0.702],["XP_028902313.1","XP_028925844.1",0.954],["XP_028902313.1","XP_028921608.1",0.594],["XP_028902313.1","XP_028917855.1",0.959],["XP_028902313.1","XP_028916712.1",0.893],["XP_028902313.1","XP_028917201.1",0.541],["XP_028914477.1","XP_001515596.2",0.876],["XP_028914477.1","XP_028925844.1",0.924],["XP_028914477.1","XP_028921608.1",0.948],["XP_028914477.1","XP_028917855.1",0.793],["XP_028914477.1","XP_028916712.1",0.942],["XP_028914477.1","XP_028917201.1",0.896],["XP_028917201.1","XP_001515596.2",0.921],["XP_028917201.1","XP_028916712.1",0.891],["XP_028917201.1","XP_028917855.1",0.766],["XP_028917201.1","XP_028921608.1",0.899],["XP_028917201.1","XP_028925844.1",0.859],["XP_028921608.1","XP_001515596.2",0.783],["XP_028921608.1","XP_028916712.1",0.775],["XP_028921608.1","XP_028917855.1",0.556],["XP_028921608.1","XP_028925844.1",0.812],["XP_001515596.2","XP_028916712.1",0.818],["XP_001515596.2","XP_028917855.1",0.559],["XP_001515596.2","XP_028925844.1",0.8],["XP_028925844.1","XP_028916712.1",0.801],["XP_028925844.1","XP_028917855.1",0.951],["XP_028917855.1","XP_028916712.1",0.763]],"all_go_terms":{"GO:0003016":1,"GO:0006062":1,"GO:0043458":1,"GO:0006069":2,"GO:0033859":1,"GO:0051160":1,"GO:0006693":1,"GO:0006633":1,"GO:1900116":1,"GO:0051409":1,"GO:0045777":1,"GO:0055114":1,"GO:1901159":1,"GO:0046688":1,"GO:0006068":2,"GO:0032496":1,"GO:0046294":1,"GO:0018119":1,"GO:0042572":2,"GO:0097327":1,"GO:0019518":2,"GO:0009809":1,"GO:0046370":1,"GO:0033498":1,"GO:0019595":1,"GO:0010430":1,"GO:0000947":1,"GO:0042573":1,"GO:0006116":1,"GO:0006351":2,"GO:0045892":1,"GO:0006104":1,"GO:0006099":1,"GO:0006085":1,"GO:0051775":1,"GO:0009102":3,"GO:0009447":3,"GO:0015995":2,"GO:0006782":3,"GO:0009089":3,"GO:0048148":2,"GO:0019878":3,"GO:0042450":2,"GO:0009413":2,"GO:0010121":2,"GO:0055129":3,"GO:0019481":2,"GO:0009450":3,"GO:0006593":2,"GO:0019483":2,"GO:0019491":2,"GO:0017000":4,"GO:0006532":1,"GO:0006686":1,"GO:0009835":1,"GO:0033362":1,"GO:0034276":1,"GO:0009103":4,"GO:0009236":1,"GO:0055089":1,"GO:0006571":1,"GO:0032869":1,"GO:0007219":1,"GO:0019551":1,"GO:0019441":1,"GO:0015908":1,"GO:0046677":1,"GO:0046511":1,"GO:0009246":1,"GO:0071555":1,"GO:0033585":1,"GO:0042218":1,"GO:0006107":1,"GO:0009243":1,"GO:0042853":1,"GO:0009245":1,"GO:0000105":1,"GO:0019550":1,"GO:0006523":1,"GO:0006783":1,"GO:0006533":1,"GO:0033512":1,"GO:0097053":1,"GO:0009862":1,"GO:0009437":1,"GO:0033539":1,"GO:1904482":1,"GO:0006231":1,"GO:0017148":1,"GO:0032259":1,"GO:0046655":1,"GO:0009113":1,"GO:0034340":1,"GO:0019264":1,"GO:0006565":1,"GO:0051289":1,"GO:0006564":4,"GO:0035999":1,"GO:0046839":3,"GO:0046196":3,"GO:0030836":3,"GO:0097171":3,"GO:0097755":3,"GO:0071318":3,"GO:0046272":3,"GO:0046050":3,"GO:0009244":3,"GO:0046295":3,"GO:0070574":3,"GO:0006825":3,"GO:0019700":3,"GO:0019373":3,"GO:0006114":3,"GO:0006470":3,"GO:0031247":3,"GO:0032361":3,"GO:0006045":3,"GO:0005975":3,"GO:0016311":3,"GO:0046380":3,"GO:0033574":3,"GO:0006874":3,"GO:0071577":3,"GO:0009855":1,"GO:0046939":1,"GO:0035115":1,"GO:0019546":1,"GO:0001568":1,"GO:0003007":1,"GO:0051591":1,"GO:0009954":1,"GO:0044210":1,"GO:0009090":1,"GO:0070384":1,"GO:0060166":1,"GO:0043584":1,"GO:0010133":1,"GO:0042904":1,"GO:0006537":1,"GO:0007494":1,"GO:0035975":1,"GO:0019545":1,"GO:0048384":1,"GO:0036293":1,"GO:0002072":1,"GO:0019285":1,"GO:0042574":1,"GO:0031016":1,"GO:0019413":1,"GO:0060013":1,"GO:0060324":1,"GO:0019877":1,"GO:0048566":1,"GO:0071300":1,"GO:0006526":1,"GO:0009088":1,"GO:1901023":1,"GO:0009258":1,"GO:0031076":1,"GO:0021983":1,"GO:0050885":1,"GO:0021915":1,"GO:0006540":1,"GO:0030900":1,"GO:0019544":1,"GO:0015976":1,"GO:0014032":1,"GO:0042472":1,"GO:0009952":1,"GO:0030902":1,"GO:0032180":1,"GO:0001936":1,"GO:0021768":1,"GO:0048738":1,"GO:0035799":1,"GO:0007584":1,"GO:0006678":1,"GO:0051790":1,"GO:0051792":1,"GO:0019367":1},"recipe_readded":[]}