{"hash":"386543985263794833","title":"Calcium signaling and mitochondrial calcium homeostasis","description":"The Top Terms strongly cluster around calcium handling and signaling, including calcium import/export across membranes and mitochondrial calcium transport plus mitochondrial calcium homeostasis. In addition, calcium-dependent signaling is supported by the protein kinase activation term, and synaptic plasticity terms (LTP/LTD) point to neuronal calcium signaling; the heart contraction term also fits calcium-dependent excitation-contraction coupling. A ribosome biogenesis term appears but is weaker in relation to the dominant calcium-centric theme, so the label emphasizes calcium signaling and calcium management in excitable tissues.","confidence":"High","size":6,"edges":5,"triangles":0,"max_degree":3,"top_function":null,"members":[{"accession":"XP_028918322.1","go_terms":["GO:0014819","GO:0098703","GO:0097369","GO:0006851","GO:0010163","GO:0060291","GO:0060292","GO:0098735","GO:1990034","GO:0007154","GO:0006828","GO:0048022","GO:0051560"]},{"accession":"XP_039770206.1","go_terms":[]},{"accession":"XP_028917782.1","go_terms":["GO:0032147","GO:0042254"]},{"accession":"XP_007653609.1","go_terms":[]},{"accession":"XP_028928732.1","go_terms":[]},{"accession":"XP_028915263.1","go_terms":["GO:0032147","GO:0042254"]}],"graph":[["XP_039770206.1","XP_007653609.1",0.549],["XP_028918322.1","XP_007653609.1",0.86],["XP_028918322.1","XP_028917782.1",0.721],["XP_028928732.1","XP_007653609.1",0.786],["XP_028928732.1","XP_028917782.1",0.886]],"all_go_terms":{"GO:0098703":1,"GO:0060292":1,"GO:0006851":1,"GO:0060291":1,"GO:1990034":1,"GO:0098735":1,"GO:0051560":1,"GO:0048022":1,"GO:0010163":1,"GO:0014819":1,"GO:0006828":1,"GO:0097369":1,"GO:0007154":1,"GO:0042254":2,"GO:0032147":2},"recipe_readded":[]}