{"hash":"353753130995806399","title":"Glycan Biosynthesis and Epithelial Polarity in Development","description":"This cluster is dominated by glycosylation-related GO terms: poly-N-acetyllactosamine biosynthesis, O-linked glycosylation via hydroxyproline, arabinogalactan protein metabolism, and Lewis a epitope biosynthesis, plus mucilage and cell-surface components. These glycan pathways are linked to developmental processes such as root hair cell development, seed coat mucilage, and maintenance of epithelial polarity/adhesion (as seen in follicular epithelium). The mix of plant-focused glycan biology (AGPs, root hairs, seed mucilage) with epithelial polarity and adhesion functions across species suggests a common theme of glycan-driven cell surface interactions shaping developmental cell connectivity. Overall, the cluster seems to represent glycan biosynthesis underlying epithelial development and cell adhesion.","confidence":"Medium","size":18,"edges":144,"triangles":688,"max_degree":17,"top_function":null,"members":[{"accession":"XP_007669377.1","go_terms":["GO:0075015","GO:0042248","GO:0010493","GO:0018258","GO:0080147","GO:0010405","GO:0030311","GO:0001744","GO:0007299","GO:0048354"]},{"accession":"XP_028902610.1","go_terms":["GO:0075015","GO:0005989","GO:0060054","GO:0060058","GO:0007341","GO:0006486","GO:0048147","GO:0018146","GO:0060055","GO:0030879","GO:0060046","GO:0007339","GO:0006688","GO:0045136","GO:0021680","GO:0008542","GO:0002526","GO:0006029"]},{"accession":"XP_028902611.1","go_terms":["GO:0075015","GO:0005989","GO:0060054","GO:0060058","GO:0007341","GO:0006486","GO:0048147","GO:0018146","GO:0060055","GO:0030879","GO:0060046","GO:0007339","GO:0006688","GO:0045136","GO:0021680","GO:0008542","GO:0002526","GO:0006029"]},{"accession":"XP_028909817.1","go_terms":["GO:0009247","GO:0009405","GO:0097502","GO:0008654","GO:0006490","GO:0033577","GO:0046488","GO:0010125","GO:0071793","GO:0009103","GO:1901133","GO:0007631","GO:0009413","GO:0009414","GO:0072708","GO:0009744","GO:0005978","GO:0005985","GO:0010555","GO:0006506","GO:0006006","GO:0019252"]},{"accession":"XP_028919240.1","go_terms":["GO:0007124","GO:0051123","GO:0043966","GO:0001403","GO:0009960","GO:0006366","GO:0016578"]},{"accession":"XP_028926545.1","go_terms":["GO:0075015","GO:0042248","GO:0010493","GO:0018258","GO:0080147","GO:0010405","GO:0030311","GO:0001744","GO:0007299","GO:0048354","GO:0055016","GO:0032092","GO:0001541","GO:0036011","GO:0045747","GO:0007386","GO:0060576","GO:0016267","GO:0002315","GO:1902367","GO:0007143"]},{"accession":"XP_028935554.1","go_terms":["GO:0035269","GO:0016266","GO:0010289","GO:0006012","GO:0005978","GO:0071555","GO:0010192","GO:0043403","GO:0010417","GO:0009834"]},{"accession":"XP_028935987.1","go_terms":["GO:0006777","GO:0009234","GO:0046677","GO:0042426","GO:0009107","GO:0009102","GO:0030488","GO:0006782","GO:0018339","GO:0070475","GO:0009249","GO:0009228","GO:0008616","GO:0018189","GO:0019475"]},{"accession":"XP_028937278.1","go_terms":["GO:0000055","GO:0032298","GO:0000398","GO:1903026","GO:0009691","GO:0034265","GO:0008033","GO:0061587"]},{"accession":"XP_028937280.1","go_terms":["GO:0009691","GO:0034265","GO:0008033","GO:0061587"]},{"accession":"XP_028908880.1","go_terms":["GO:0005975","GO:0006487"]},{"accession":"XP_007666228.2","go_terms":["GO:0032922","GO:2000323","GO:0071000","GO:2000850","GO:0019915","GO:0009650","GO:0045475","GO:1902448","GO:0009638","GO:0042332","GO:0050980","GO:0009584","GO:0050958","GO:0048574","GO:0009588","GO:0033762","GO:1902347","GO:0006975","GO:0000719","GO:0042754","GO:0018298","GO:0009785","GO:0009646","GO:0010117","GO:0010343","GO:1901371","GO:1901332","GO:0010617","GO:0010075","GO:1901672","GO:0010244","GO:0045187","GO:2000001","GO:0043153","GO:0010118"]},{"accession":"XP_028935073.1","go_terms":["GO:0032922","GO:2000323","GO:0071000","GO:2000850","GO:0019915","GO:0009650","GO:0045475","GO:1902448","GO:0009638","GO:0042332","GO:0050980","GO:0009584","GO:0050958","GO:0048574","GO:0009588","GO:0033762","GO:1902347","GO:0006975","GO:0000719","GO:0042754","GO:0018298","GO:0009785","GO:0009646","GO:0010117","GO:0010343","GO:1901371","GO:1901332","GO:0010617","GO:0010075","GO:1901672","GO:0010244","GO:0045187","GO:2000001","GO:0043153","GO:0010118"]},{"accession":"XP_028905494.1","go_terms":["GO:0075015","GO:0042248","GO:0010493","GO:0018258","GO:0080147","GO:0010405","GO:0030311","GO:0001744","GO:0007299","GO:0048354"]},{"accession":"XP_028913426.1","go_terms":["GO:0035269","GO:0016266","GO:0010289","GO:0006012","GO:0005978","GO:0071555","GO:0010192","GO:0043403","GO:0010417","GO:0009834"]},{"accession":"XP_007665392.1","go_terms":["GO:0075015","GO:0042248","GO:0010493","GO:0018258","GO:0080147","GO:0010405","GO:0030311","GO:0001744","GO:0007299","GO:0048354"]},{"accession":"XP_028935911.1","go_terms":["GO:0070592","GO:0071769","GO:0045227","GO:0052573","GO:0036108","GO:0016266","GO:0030244","GO:0019350","GO:0071555","GO:0006011","GO:0018242","GO:0018243","GO:0030213","GO:0002378"]},{"accession":"XP_028934611.1","go_terms":["GO:0001576","GO:0036210","GO:0051999"]}],"graph":[["XP_028926545.1","XP_007666228.2",0.609],["XP_028926545.1","XP_007669377.1",0.754],["XP_028926545.1","XP_028902610.1",0.7],["XP_028926545.1","XP_028902611.1",0.92],["XP_028926545.1","XP_028905494.1",0.843],["XP_028926545.1","XP_028908880.1",0.703],["XP_028926545.1","XP_028913426.1",0.783],["XP_028926545.1","XP_028934611.1",0.852],["XP_028926545.1","XP_028935554.1",0.626],["XP_028926545.1","XP_028935911.1",0.847],["XP_028926545.1","XP_028935987.1",0.847],["XP_028926545.1","XP_028937280.1",0.806],["XP_028937278.1","XP_007665392.1",0.971],["XP_028937278.1","XP_007666228.2",0.904],["XP_028937278.1","XP_007669377.1",0.644],["XP_028937278.1","XP_028902611.1",0.916],["XP_028937278.1","XP_028905494.1",0.731],["XP_028937278.1","XP_028908880.1",0.936],["XP_028937278.1","XP_028909817.1",0.603],["XP_0289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