{"hash":"243709373826249558","title":"Mitochondrial respiration and membrane protein targeting","description":"This cluster is dominated by GO terms for mitochondrial electron transport and aerobic respiration, indicating a core role in energy production. Additional terms point to membrane-associated protein trafficking and targeting (SRP-dependent cotranslational translocation, ER-to-cytosol transport), suggesting coordinated processes of proteins being directed to membranes, including mitochondria and the ER. The mix suggests a cluster of proteins involved in respiration with related membrane targeting and translocation functions, reflecting how energy production is coupled to co-translational trafficking.","confidence":"High","size":12,"edges":60,"triangles":165,"max_degree":11,"top_function":null,"members":[{"accession":"XP_015005532.1","go_terms":["GO:1902600","GO:0009060","GO:0006122","GO:0034551"]},{"accession":"NP_001253867.1","go_terms":["GO:0043547","GO:0000060","GO:0030970","GO:0006616","GO:0030433","GO:0031204"]},{"accession":"YP_026115.1","go_terms":[]},{"accession":"XP_014987599.1","go_terms":["GO:0042628","GO:0050729","GO:0006058","GO:0072378","GO:0043163","GO:0051260","GO:0060445","GO:0043123","GO:0010838","GO:0030216","GO:0048661","GO:0018153","GO:0043277","GO:0031069","GO:0060662","GO:0031424","GO:0007200","GO:0051482","GO:0001974","GO:0006517","GO:0032471"]},{"accession":"NP_001180745.1","go_terms":["GO:0019896","GO:0008090","GO:0097211","GO:0006626","GO:0071456","GO:0008089","GO:0010822","GO:1902510","GO:0071383"]},{"accession":"XP_028686374.1","go_terms":[]},{"accession":"XP_028709289.1","go_terms":["GO:0000002","GO:0030150","GO:0045039","GO:0032094","GO:0045037"]},{"accession":"NP_001244519.1","go_terms":["GO:0010259","GO:0043457","GO:0000422"]},{"accession":"XP_028700845.1","go_terms":[]},{"accession":"YP_026109.1","go_terms":["GO:0042777","GO:0099132"]},{"accession":"NP_001181159.1","go_terms":["GO:0046196","GO:0030836","GO:0006470","GO:0046050","GO:0032361","GO:0006114","GO:0071318","GO:0031247"]},{"accession":"XP_001114543.1","go_terms":["GO:0046944"]}],"graph":[["YP_026109.1","XP_001114543.1",0.988],["YP_026109.1","XP_014987599.1",0.979],["YP_026109.1","XP_015005532.1",0.947],["YP_026109.1","XP_028686374.1",0.93],["YP_026109.1","XP_028700845.1",0.967],["YP_026109.1","XP_028709289.1",0.943],["YP_026109.1","YP_026115.1",0.971],["YP_026109.1","NP_001180745.1",0.978],["YP_026109.1","NP_001181159.1",0.854],["YP_026109.1","NP_001244519.1",0.878],["YP_026109.1","NP_001253867.1",0.942],["XP_014987599.1","XP_015005532.1",0.937],["XP_014987599.1","XP_028686374.1",0.939],["XP_014987599.1","XP_028709289.1",0.937],["XP_014987599.1","YP_026115.1",0.889],["XP_014987599.1","NP_001180745.1",0.897],["XP_014987599.1","NP_001181159.1",0.638],["XP_014987599.1","NP_001244519.1",0.925],["XP_014987599.1","NP_001253867.1",0.981],["XP_014987599.1","XP_001114543.1",0.719],["NP_001180745.1","NP_001253867.1",0.976],["NP_001180745.1","NP_001244519.1",0.922],["NP_001180745.1","XP_001114543.1",0.917],["NP_001180745.1","XP_015005532.1",0.961],["NP_001180745.1","XP_028709289.1",0.984],["NP_001180745.1","YP_026115.1",0.883],["NP_001180745.1","XP_028700845.1",0.807],["NP_001180745.1","XP_028686374.1",0.954],["NP_001253867.1","NP_001181159.1",0.978],["NP_001253867.1","XP_001114543.1",0.846],["NP_001253867.1","XP_028686374.1",0.766],["NP_001253867.1","XP_028700845.1",0.93],["NP_001253867.1","XP_028709289.1",0.955],["NP_001253867.1","YP_026115.1",0.74],["NP_001244519.1","NP_001181159.1",0.957],["NP_001244519.1","XP_001114543.1",0.956],["NP_001244519.1","XP_015005532.1",0.943],["NP_001244519.1","XP_028709289.1",0.977],["NP_001244519.1","YP_026115.1",0.928],["NP_001244519.1","XP_028700845.1",0.681],["NP_001244519.1","XP_028686374.1",0.951],["XP_028709289.1","XP_001114543.1",0.978],["XP_028709289.1","XP_015005532.1",0.951],["XP_028709289.1","XP_028686374.1",0.964],["XP_028709289.1","XP_028700845.1",0.93],["XP_028709289.1","YP_026115.1",0.98],["XP_028709289.1","NP_001181159.1",0.978],["XP_028700845.1","XP_001114543.1",0.781],["XP_028700845.1","XP_015005532.1",0.726],["XP_028700845.1","XP_028686374.1",0.851],["XP_028700845.1","YP_026115.1",0.93],["NP_001181159.1","XP_015005532.1",0.754],["NP_001181159.1","YP_026115.1",0.973],["NP_001181159.1","XP_028686374.1",0.884],["XP_015005532.1","YP_026115.1",0.709],["XP_015005532.1","XP_028686374.1",0.628],["XP_015005532.1","XP_001114543.1",0.97],["XP_001114543.1","YP_026115.1",0.857],["XP_001114543.1","XP_028686374.1",0.964],["YP_026115.1","XP_028686374.1",0.937]],"all_go_terms":{"GO:0034551":1,"GO:0006122":1,"GO:1902600":1,"GO:0009060":1,"GO:0030433":1,"GO:0030970":1,"GO:0031204":1,"GO:0000060":1,"GO:0006616":1,"GO:0043547":1,"GO:0060662":1,"GO:0001974":1,"GO:0051260":1,"GO:0042628":1,"GO:0010838":1,"GO:0032471":1,"GO:0050729":1,"GO:0048661":1,"GO:0031069":1,"GO:0031424":1,"GO:0060445":1,"GO:0030216":1,"GO:0006517":1,"GO:0007200":1,"GO:0051482":1,"GO:0006058":1,"GO:0018153":1,"GO:0043277":1,"GO:0072378":1,"GO:0043123":1,"GO:0043163":1,"GO:0008089":1,"GO:1902510":1,"GO:0008090":1,"GO:0006626":1,"GO:0071456":1,"GO:0071383":1,"GO:0019896":1,"GO:0010822":1,"GO:0097211":1,"GO:0000002":1,"GO:0030150":1,"GO:0045037":1,"GO:0032094":1,"GO:0045039":1,"GO:0000422":1,"GO:0043457":1,"GO:0010259":1,"GO:0099132":1,"GO:0042777":1,"GO:0032361":1,"GO:0071318":1,"GO:0006470":1,"GO:0031247":1,"GO:0006114":1,"GO:0046050":1,"GO:0046196":1,"GO:0030836":1,"GO:0046944":1},"recipe_readded":[]}