{"hash":"1292240571991682404","title":"Kinase signaling and phosphorylation","description":"The top GO terms strongly point to phosphorylation-related processes, including protein autophosphorylation and peptidyl-histidine phosphorylation, which suggests kinase activity driving signaling. The oxidative stress term (cellular response to hydrogen peroxide) can be downstream of such signaling. Some terms like DNA replication and nucleotide biosynthesis are less tightly connected to signaling, but the phosphorylation-focused terms provide the clearest cohesive theme for this cluster.","confidence":"Medium","size":9,"edges":28,"triangles":40,"max_degree":8,"top_function":"DNA repair","members":[{"accession":"NP_001247759.1","go_terms":["GO:0042795","GO:0006367","GO:0001174","GO:0001111","GO:0080163","GO:0006370","GO:0006368","GO:0070940","GO:0050434","GO:0032968","GO:0043085","GO:0010467"]},{"accession":"XP_014980795.1","go_terms":["GO:0018106","GO:0045920","GO:0061508","GO:0002762","GO:0030819","GO:0006228","GO:0046777","GO:0048515","GO:0071333","GO:0045618","GO:0051259","GO:0071398","GO:0048550","GO:0070301","GO:0006241","GO:0050765","GO:0010976","GO:0006187","GO:0006186","GO:0006183","GO:0006897","GO:0007399","GO:0060416"]},{"accession":"XP_028696210.1","go_terms":["GO:0018106","GO:0045920","GO:0061508","GO:0002762","GO:0030819","GO:0006228","GO:0046777","GO:0048515","GO:0071333","GO:0045618","GO:0051259","GO:0071398","GO:0048550","GO:0070301","GO:0006241","GO:0050765","GO:0010976","GO:0006187","GO:0006186","GO:0006183","GO:0006897","GO:0007399","GO:0060416"]},{"accession":"XP_028696211.1","go_terms":["GO:0018106","GO:0045920","GO:0061508","GO:0002762","GO:0030819","GO:0006228","GO:0046777","GO:0048515","GO:0071333","GO:0045618","GO:0051259","GO:0071398","GO:0048550","GO:0070301","GO:0006241","GO:0050765","GO:0010976","GO:0006187","GO:0006186","GO:0006183","GO:0006897","GO:0007399","GO:0060416"]},{"accession":"XP_014977486.1","go_terms":["GO:0071494","GO:0006297","GO:0042276","GO:0070987","GO:0006261","GO:0002206","GO:0000448"]},{"accession":"XP_014991918.2","go_terms":["GO:0071494","GO:0006297","GO:0042276","GO:0070987","GO:0006261"]},{"accession":"XP_028688349.1","go_terms":["GO:0000738","GO:0000289","GO:0002107","GO:0010606","GO:0006281","GO:0006261","GO:0000467","GO:0008033","GO:0034415","GO:0031047"]},{"accession":"NP_001180742.1","go_terms":["GO:0000738","GO:0000289","GO:0002107","GO:0010606","GO:0006281","GO:0006261","GO:0000467","GO:0008033","GO:0034415","GO:0031047"]},{"accession":"NP_001253019.1","go_terms":["GO:0030466","GO:0006297","GO:0006296","GO:0034087","GO:0035753","GO:0000083","GO:1902990","GO:0070914","GO:0042769","GO:0007064","GO:0032355","GO:0006348","GO:1900264","GO:0042276","GO:0006266","GO:0006260","GO:0045740","GO:0030855","GO:0046686","GO:0031297","GO:1903364","GO:0070301","GO:0006283","GO:0000722","GO:0006273","GO:0071548","GO:0016925","GO:1902065","GO:0007507","GO:0097421","GO:1902394","GO:0070987","GO:0044849","GO:1903022","GO:0006977","GO:0006272","GO:0045739","GO:0000710","GO:0071479","GO:0051321","GO:0031573","GO:0006281","GO:1902231","GO:0051598","GO:0000076","GO:0000077","GO:0090305","GO:0021762","GO:0007131"]}],"graph":[["XP_014980795.1","XP_014977486.1",0.939],["XP_014980795.1","XP_014991918.2",0.8],["XP_014980795.1","XP_028688349.1",0.714],["XP_014980795.1","XP_028696210.1",0.978],["XP_014980795.1","XP_028696211.1",0.914],["XP_014980795.1","NP_001180742.1",0.957],["XP_028688349.1","XP_014977486.1",0.868],["XP_028688349.1","XP_014991918.2",0.794],["XP_028688349.1","XP_028696210.1",0.909],["XP_028688349.1","XP_028696211.1",0.905],["XP_028688349.1","NP_001180742.1",0.545],["XP_028688349.1","NP_001253019.1",0.535],["NP_001180742.1","XP_014977486.1",0.716],["NP_001180742.1","XP_014991918.2",0.558],["NP_001180742.1","XP_028696210.1",0.977],["NP_001180742.1","XP_028696211.1",0.751],["XP_014977486.1","XP_014991918.2",0.806],["XP_014977486.1","XP_028696210.1",0.967],["XP_014977486.1","XP_028696211.1",0.93],["XP_014977486.1","NP_001247759.1",0.913],["XP_014977486.1","NP_001253019.1",0.655],["XP_014991918.2","XP_028696210.1",0.953],["XP_014991918.2","XP_028696211.1",0.855],["XP_014991918.2","NP_001247759.1",0.919],["XP_014991918.2","NP_001253019.1",0.547],["XP_028696211.1","NP_001247759.1",0.963],["NP_001253019.1","NP_001247759.1",0.749],["XP_028696210.1","NP_001247759.1",0.963]],"all_go_terms":{"GO:0042795":1,"GO:0070940":1,"GO:0001111":1,"GO:0080163":1,"GO:0043085":1,"GO:0001174":1,"GO:0010467":1,"GO:0006367":1,"GO:0050434":1,"GO:0006370":1,"GO:0032968":1,"GO:0006368":1,"GO:0030819":3,"GO:0051259":3,"GO:0046777":3,"GO:0006228":3,"GO:0071333":3,"GO:0002762":3,"GO:0070301":4,"GO:0050765":3,"GO:0018106":3,"GO:0006897":3,"GO:0061508":3,"GO:0010976":3,"GO:0006183":3,"GO:0071398":3,"GO:0045920":3,"GO:0006186":3,"GO:0006187":3,"GO:0048515":3,"GO:0045618":3,"GO:0006241":3,"GO:0007399":3,"GO:0048550":3,"GO:0060416":3,"GO:0071494":2,"GO:0000448":1,"GO:0070987":3,"GO:0042276":3,"GO:0002206":1,"GO:0006261":4,"GO:0006297":3,"GO:0008033":2,"GO:0002107":2,"GO:0000738":2,"GO:0006281":3,"GO:0000289":2,"GO:0010606":2,"GO:0000467":2,"GO:0031047":2,"GO:0034415":2,"GO:0030855":1,"GO:0031297":1,"GO:0006348":1,"GO:0051598":1,"GO:0042769":1,"GO:0030466":1,"GO:0045739":1,"GO:0000722":1,"GO:0006273":1,"GO:1900264":1,"GO:0046686":1,"GO:0035753":1,"GO:1902394":1,"GO:0006977":1,"GO:0000076":1,"GO:0006266":1,"GO:0007507":1,"GO:0006296":1,"GO:0071479":1,"GO:0007064":1,"GO:0000083":1,"GO:0044849":1,"GO:0031573":1,"GO:1902990":1,"GO:0007131":1,"GO:1902065":1,"GO:0070914":1,"GO:0006272":1,"GO:0006260":1,"GO:1903022":1,"GO:0032355":1,"GO:0034087":1,"GO:0021762":1,"GO:0006283":1,"GO:1903364":1,"GO:0000710":1,"GO:1902231":1,"GO:0097421":1,"GO:0000077":1,"GO:0051321":1,"GO:0090305":1,"GO:0045740":1,"GO:0071548":1,"GO:0016925":1},"recipe_readded":[]}