{"hash":"663121778889446080","title":"Central metabolism and redox balance","description":"The proteins cluster around core energy production and redox regulation: glycolysis, the TCA cycle, 2-oxoglutarate and leucine catabolic pathways feed into energy metabolism; glutathione metabolism and protein glutathionylation indicate redox control, while accompanying processes like translation and vacuolar acidification suggest a housekeeping module coordinating metabolism and ion/protein homeostasis.","confidence":"Medium","size":17,"edges":136,"triangles":680,"max_degree":16,"top_function":null,"members":[{"accession":"NP_001156935.1","go_terms":[]},{"accession":"NP_008085.1","go_terms":[]},{"accession":"XP_623779.1","go_terms":[]},{"accession":"NP_001229585.1","go_terms":["GO:0007033","GO:0006878","GO:0015991","GO:0006626","GO:0007035","GO:0006623","GO:0042777","GO:0006814"]},{"accession":"XP_001121159.1","go_terms":["GO:0006259","GO:0090305","GO:0006412"]},{"accession":"XP_001122727.1","go_terms":[]},{"accession":"XP_003249139.1","go_terms":["GO:0070276","GO:0042391","GO:0000305","GO:0019383","GO:0043448","GO:0006550","GO:0009106","GO:0006212","GO:0048240","GO:0006096","GO:0051068","GO:0043046","GO:0007369","GO:0036245","GO:0006749","GO:0009228","GO:0019646","GO:0046653","GO:0045454","GO:0042128","GO:0007568","GO:0097054","GO:0006552","GO:0042208","GO:0006120","GO:0019430","GO:0050787","GO:0010731","GO:0006103","GO:0006214","GO:0019483"]},{"accession":"XP_006570132.1","go_terms":[]},{"accession":"XP_026298925.1","go_terms":["GO:0051726","GO:1902476","GO:0060315","GO:1902000","GO:0010880","GO:0051881","GO:0045669","GO:0070527","GO:0009072","GO:0019852","GO:0009407","GO:0042594","GO:0014810","GO:0060316","GO:0006289","GO:0098869","GO:0010731","GO:0006749","GO:0045454","GO:0071243","GO:0003147","GO:0009263","GO:0071473","GO:0030416","GO:0080058","GO:1903026","GO:2000651","GO:0034599","GO:0055114"]},{"accession":"XP_392023.1","go_terms":[]},{"accession":"XP_392654.2","go_terms":["GO:0031564","GO:0000462","GO:0006412"]},{"accession":"XP_392655.2","go_terms":["GO:0097428","GO:0006879","GO:0009399","GO:0016226"]},{"accession":"XP_392679.5","go_terms":["GO:0043617","GO:0006086","GO:0000002","GO:0006099","GO:0006103","GO:0033512","GO:0006096","GO:0006814","GO:2001295","GO:0042759","GO:0006552","GO:0006213","GO:0006094"]},{"accession":"XP_393876.1","go_terms":["GO:0008585","GO:0006099","GO:0006097","GO:0019878","GO:1903976","GO:0006749","GO:0071071","GO:0006740","GO:0009098","GO:1904465","GO:0060253","GO:0006979","GO:0006537","GO:0006741","GO:0006103","GO:0006102","GO:0060696","GO:0048545"]},{"accession":"XP_395548.2","go_terms":["GO:0036265","GO:0006718","GO:0035572","GO:0035573","GO:0001887","GO:0014075","GO:0002347","GO:0070555","GO:0036068","GO:0018012","GO:0018013","GO:0006972","GO:0042220","GO:0002098","GO:0019505","GO:0035902","GO:0006370","GO:0009877","GO:0046690","GO:1901052","GO:0009236","GO:0017000","GO:0035690","GO:0006656","GO:0019919","GO:0009102","GO:0030488","GO:0016049","GO:0006744","GO:0010189","GO:0016126","GO:0043985","GO:0070476","GO:0000056","GO:0001300","GO:0090398","GO:0030961","GO:0031167","GO:0018364","GO:0018026","GO:0018027","GO:0032259","GO:0042214","GO:0071768","GO:0006596","GO:0000154"]},{"accession":"XP_623181.2","go_terms":["GO:0019082","GO:0071169","GO:1904815","GO:0039548","GO:0039520","GO:0039648","GO:0033128","GO:0060701","GO:0039579","GO:0051572","GO:0034184","GO:0007549","GO:0051725","GO:1900231","GO:0039694","GO:0061086","GO:0045618","GO:0039595","GO:1901837"]},{"accession":"XP_624508.1","go_terms":["GO:1901006"]}],"graph":[["NP_001156935.1","NP_001229585.1",0.969],["NP_001156935.1","NP_008085.1",0.918],["NP_001156935.1","XP_001121159.1",0.961],["NP_001156935.1","XP_001122727.1",0.969],["NP_001156935.1","XP_003249139.1",0.983],["NP_001156935.1","XP_006570132.1",0.969],["NP_001156935.1","XP_026298925.1",0.988],["NP_001156935.1","XP_392023.1",0.983],["NP_001156935.1","XP_392654.2",0.973],["NP_001156935.1","XP_392655.2",0.923],["NP_001156935.1","XP_392679.5",0.981],["NP_001156935.1","XP_393876.1",0.989],["NP_001156935.1","XP_395548.2",0.986],["NP_001156935.1","XP_623181.2",0.986],["NP_001156935.1","XP_623779.1",0.967],["NP_001156935.1","XP_624508.1",0.986],["XP_624508.1","NP_001229585.1",0.956],["XP_624508.1","NP_008085.1",0.959],["XP_624508.1","XP_001121159.1",0.973],["XP_624508.1","XP_001122727.1",0.958],["XP_624508.1","XP_003249139.1",0.958],["XP_624508.1","XP_006570132.1",0.955],["XP_624508.1","XP_026298925.1",0.991],["XP_624508.1","XP_392023.1",0.989],["XP_624508.1","XP_392654.2",0.983],["XP_624508.1","XP_392655.2",0.966],["XP_624508.1","XP_392679.5",0.94],["XP_624508.1","XP_393876.1",0.957],["XP_624508.1","XP_395548.2",0.973],["XP_624508.1","XP_623181.2",0.989],["XP_624508.1","XP_623779.1",0.987],["XP_392023.1","NP_001229585.1",0.976],["XP_392023.1","NP_008085.1",0.974],["XP_392023.1","XP_001121159.1",0.987],["XP_392023.1","XP_001122727.1",0.963],["XP_392023.1","XP_003249139.1",0.99],["XP_392023.1","XP_006570132.1",0.975],["XP_392023.1","XP_026298925.1",0.99],["XP_392023.1","XP_623181.2",0.986],["XP_392023.1","XP_623779.1",0.984],["XP_392023.1","XP_395548.2",0.99],["XP_392023.1","XP_392654.2",0.976],["XP_392023.1","XP_392655.2",0.948],["XP_392023.1","XP_392679.5",0.988],["XP_392023.1","XP_393876.1",0.991],["NP_008085.1","NP_001229585.1",0.938],["NP_008085.1","XP_001121159.1",0.956],["NP_008085.1","XP_001122727.1",0.952],["NP_008085.1","XP_003249139.1",0.945],["NP_008085.1","XP_006570132.1",0.946],["NP_008085.1","XP_026298925.1",0.984],["NP_008085.1","XP_392654.2",0.933],["NP_008085.1","XP_392655.2",0.947],["NP_008085.1","XP_392679.5",0.978],["NP_008085.1","XP_393876.1",0.981],["NP_008085.1","XP_395548.2",0.982],["NP_008085.1","XP_623181.2",0.977],["NP_008085.1","XP_623779.1",0.888],["XP_026298925.1","NP_001229585.1",0.947],["XP_026298925.1","XP_001121159.1",0.986],["XP_026298925.1","XP_001122727.1",0.972],["XP_026298925.1","XP_003249139.1",0.907],["XP_026298925.1","XP_006570132.1",0.899],["XP_026298925.1","XP_623181.2",0.989],["XP_026298925.1","XP_623779.1",0.973],["XP_026298925.1","XP_395548.2",0.965],["XP_026298925.1","XP_393876.1",0.911],["XP_026298925.1","XP_392654.2",0.984],["XP_026298925.1","XP_392655.2",0.972],["XP_026298925.1","XP_392679.5",0.964],["NP_001229585.1","XP_001121159.1",0.985],["NP_001229585.1","XP_001122727.1",0.928],["NP_001229585.1","XP_003249139.1",0.985],["NP_001229585.1","XP_006570132.1",0.915],["NP_001229585.1","XP_392654.2",0.961],["NP_001229585.1","XP_392655.2",0.957],["NP_001229585.1","XP_392679.5",0.981],["NP_001229585.1","XP_393876.1",0.964],["NP_001229585.1","XP_395548.2",0.951],["NP_001229585.1","XP_623181.2",0.919],["NP_001229585.1","XP_623779.1",0.974],["XP_392654.2","XP_001121159.1",0.939],["XP_392654.2","XP_001122727.1",0.977],["XP_392654.2","XP_003249139.1",0.866],["XP_392654.2","XP_006570132.1",0.966],["XP_392654.2","XP_623181.2",0.988],["XP_392654.2","XP_623779.1",0.983],["XP_392654.2","XP_395548.2",0.949],["XP_392654.2","XP_392655.2",0.962],["XP_392654.2","XP_392679.5",0.928],["XP_392654.2","XP_393876.1",0.845],["XP_001121159.1","XP_006570132.1",0.976],["XP_001121159.1","XP_001122727.1",0.986],["XP_001121159.1","XP_003249139.1",0.982],["XP_001121159.1","XP_623181.2",0.977],["XP_001121159.1","XP_623779.1",0.955],["XP_001121159.1","XP_395548.2",0.987],["XP_001121159.1","XP_393876.1",0.987],["XP_001121159.1","XP_392655.2",0.974],["XP_001121159.1","XP_392679.5",0.988],["XP_006570132.1","XP_001122727.1",0.921],["XP_006570132.1","XP_003249139.1",0.949],["XP_006570132.1","XP_623181.2",0.859],["XP_006570132.1","XP_623779.1",0.97],["XP_006570132.1","XP_395548.2",0.976],["XP_006570132.1","XP_393876.1",0.98],["XP_006570132.1","XP_392655.2",0.928],["XP_006570132.1","XP_392679.5",0.979],["XP_623779.1","XP_001122727.1",0.977],["XP_623779.1","XP_003249139.1",0.976],["XP_623779.1","XP_392655.2",0.922],["XP_623779.1","XP_392679.5",0.984],["XP_623779.1","XP_393876.1",0.976],["XP_623779.1","XP_395548.2",0.985],["XP_623779.1","XP_623181.2",0.984],["XP_395548.2","XP_001122727.1",0.986],["XP_395548.2","XP_003249139.1",0.955],["XP_395548.2","XP_392655.2",0.981],["XP_395548.2","XP_392679.5",0.964],["XP_395548.2","XP_393876.1",0.894],["XP_395548.2","XP_623181.2",0.904],["XP_392679.5","XP_001122727.1",0.974],["XP_392679.5","XP_003249139.1",0.992],["XP_392679.5","XP_623181.2",0.978],["XP_392679.5","XP_392655.2",0.76],["XP_392679.5","XP_393876.1",0.806],["XP_392655.2","XP_001122727.1",0.976],["XP_392655.2","XP_003249139.1",0.933],["XP_392655.2","XP_623181.2",0.965],["XP_392655.2","XP_393876.1",0.937],["XP_393876.1","XP_001122727.1",0.978],["XP_393876.1","XP_003249139.1",0.973],["XP_393876.1","XP_623181.2",0.898],["XP_623181.2","XP_001122727.1",0.97],["XP_623181.2","XP_003249139.1",0.855],["XP_003249139.1","XP_001122727.1",0.985]],"all_go_terms":{"GO:0007035":1,"GO:0006623":1,"GO:0042777":1,"GO:0015991":1,"GO:0007033":1,"GO:0006814":2,"GO:0006878":1,"GO:0006626":1,"GO:0006412":2,"GO:0006259":1,"GO:0090305":1,"GO:0009106":1,"GO:0051068":1,"GO:0070276":1,"GO:0019646":1,"GO:0019483":1,"GO:0019383":1,"GO:0046653":1,"GO:0043448":1,"GO:0009228":1,"GO:0006212":1,"GO:0007568":1,"GO:0006103":3,"GO:0006749":3,"GO:0006120":1,"GO:0007369":1,"GO:0042208":1,"GO:0045454":2,"GO:0097054":1,"GO:0006096":2,"GO:0006552":2,"GO:0050787":1,"GO:0019430":1,"GO:0042391":1,"GO:0048240":1,"GO:0006214":1,"GO:0006550":1,"GO:0042128":1,"GO:0010731":2,"GO:0043046":1,"GO:0000305":1,"GO:0036245":1,"GO:0070527":1,"GO:2000651":1,"GO:0098869":1,"GO:0009407":1,"GO:0071473":1,"GO:0009072":1,"GO:0045669":1,"GO:1903026":1,"GO:0060315":1,"GO:0014810":1,"GO:0080058":1,"GO:0071243":1,"GO:0019852":1,"GO:0055114":1,"GO:0060316":1,"GO:0051881":1,"GO:0006289":1,"GO:0030416":1,"GO:0010880":1,"GO:0042594":1,"GO:0009263":1,"GO:0034599":1,"GO:1902000":1,"GO:0051726":1,"GO:0003147":1,"GO:1902476":1,"GO:0000462":1,"GO:0031564":1,"GO:0009399":1,"GO:0016226":1,"GO:0006879":1,"GO:0097428":1,"GO:0033512":1,"GO:0000002":1,"GO:0042759":1,"GO:0006094":1,"GO:0043617":1,"GO:0006099":2,"GO:0006086":1,"GO:2001295":1,"GO:0006213":1,"GO:0006537":1,"GO:0009098":1,"GO:0008585":1,"GO:0006102":1,"GO:0006097":1,"GO:1904465":1,"GO:0006979":1,"GO:0060253":1,"GO:0071071":1,"GO:0019878":1,"GO:0048545":1,"GO:0006741":1,"GO:0006740":1,"GO:0060696":1,"GO:1903976":1,"GO:0042220":1,"GO:0036265":1,"GO:0000056":1,"GO:0006656":1,"GO:0001300":1,"GO:0035573":1,"GO:0009236":1,"GO:0018013":1,"GO:0035690":1,"GO:0006718":1,"GO:0002098":1,"GO:0006744":1,"GO:0016049":1,"GO:0006596":1,"GO:0071768":1,"GO:0000154":1,"GO:0070476":1,"GO:0090398":1,"GO:0010189":1,"GO:0042214":1,"GO:0017000":1,"GO:0036068":1,"GO:0018027":1,"GO:0014075":1,"GO:0006972":1,"GO:0032259":1,"GO:0006370":1,"GO:0018012":1,"GO:0070555":1,"GO:0009102":1,"GO:0016126":1,"GO:0031167":1,"GO:0030961":1,"GO:0030488":1,"GO:0043985":1,"GO:0001887":1,"GO:0009877":1,"GO:0018026":1,"GO:0019505":1,"GO:0019919":1,"GO:0046690":1,"GO:0018364":1,"GO:0035572":1,"GO:1901052":1,"GO:0002347":1,"GO:0035902":1,"GO:1904815":1,"GO:0039579":1,"GO:0060701":1,"GO:0019082":1,"GO:0039694":1,"GO:0045618":1,"GO:0051572":1,"GO:0039520":1,"GO:0033128":1,"GO:1901837":1,"GO:0051725":1,"GO:0071169":1,"GO:0039595":1,"GO:0039548":1,"GO:0039648":1,"GO:0007549":1,"GO:0061086":1,"GO:1900231":1,"GO:0034184":1,"GO:1901006":1},"recipe_readded":[]}