{"hash":"2270989358818138340","title":"Mitochondrial stress and apoptosis signaling","description":"This cluster centers on mitochondrial involvement in cellular stress and apoptosis, as indicated by terms like protein insertion into the mitochondrial inner membrane, intrinsic and extrinsic apoptotic signaling, and ROS metabolic processes. The presence of NF-kappaB signaling and interferon-beta response terms suggests concurrent inflammatory/stress signaling, while retinoic acid response points to broader differentiation-related signaling that can intersect stress pathways. Together, these terms depict a cohesive theme of mitochondrial stress driving apoptotic and inflammatory signaling responses.","confidence":"Medium","size":3,"edges":3,"triangles":1,"max_degree":2,"top_function":null,"members":[{"accession":"XP_001120479.1","go_terms":[]},{"accession":"XP_006558285.1","go_terms":["GO:0035458","GO:0071300","GO:0045732","GO:0097191","GO:0072593","GO:0045039","GO:0043280","GO:2001243"]},{"accession":"XP_026301705.1","go_terms":["GO:0007166","GO:0034197","GO:0071726","GO:0043654","GO:0010899","GO:0043123","GO:0035073","GO:0007608","GO:0035071","GO:0007604","GO:0030299","GO:0050830","GO:0043534","GO:0042992","GO:1905123","GO:2000121","GO:0060907","GO:0050731","GO:0033552","GO:0010886","GO:0070508","GO:0071447","GO:0071444","GO:0032735","GO:0030194","GO:0034375","GO:0001954","GO:0019934","GO:0070328","GO:0032497","GO:0044130","GO:0050702","GO:0044539","GO:0032760","GO:2000379","GO:0006622","GO:0006955","GO:0002755","GO:0034383","GO:0034384","GO:0035634","GO:0043691","GO:0051000","GO:0038124","GO:0016063","GO:0000122","GO:1900227","GO:0043277","GO:0060100","GO:0070543","GO:0042953","GO:0071222","GO:0071223","GO:2000505","GO:0055096","GO:0010867","GO:0010744","GO:0006702","GO:2000334","GO:0006707","GO:0050911","GO:1990000","GO:0007263","GO:0035461","GO:0033344","GO:0032755","GO:0001935","GO:0046867"]}],"graph":[["XP_026301705.1","XP_001120479.1",0.957],["XP_026301705.1","XP_006558285.1",0.963],["XP_006558285.1","XP_001120479.1",0.956]],"all_go_terms":{"GO:0045039":1,"GO:0043280":1,"GO:0071300":1,"GO:0045732":1,"GO:2001243":1,"GO:0097191":1,"GO:0072593":1,"GO:0035458":1,"GO:0035073":1,"GO:0043123":1,"GO:2000121":1,"GO:0044130":1,"GO:0050830":1,"GO:0035071":1,"GO:0070508":1,"GO:0043654":1,"GO:1900227":1,"GO:0050731":1,"GO:0042953":1,"GO:0006955":1,"GO:0071222":1,"GO:0060100":1,"GO:0034384":1,"GO:0006707":1,"GO:0035461":1,"GO:0007166":1,"GO:0043534":1,"GO:0034197":1,"GO:0034375":1,"GO:0002755":1,"GO:0038124":1,"GO:0010867":1,"GO:0010899":1,"GO:0007604":1,"GO:0010886":1,"GO:0010744":1,"GO:2000505":1,"GO:0007263":1,"GO:0033552":1,"GO:0016063":1,"GO:0034383":1,"GO:0035634":1,"GO:0030194":1,"GO:0006702":1,"GO:0043691":1,"GO:0051000":1,"GO:0006622":1,"GO:0070543":1,"GO:0030299":1,"GO:1990000":1,"GO:0001954":1,"GO:0071444":1,"GO:1905123":1,"GO:0071223":1,"GO:0033344":1,"GO:0070328":1,"GO:0050702":1,"GO:0060907":1,"GO:0032755":1,"GO:0050911":1,"GO:0044539":1,"GO:0032497":1,"GO:0032760":1,"GO:0019934":1,"GO:0071447":1,"GO:0042992":1,"GO:0032735":1,"GO:0055096":1,"GO:0007608":1,"GO:0000122":1,"GO:0043277":1,"GO:2000334":1,"GO:0046867":1,"GO:2000379":1,"GO:0001935":1,"GO:0071726":1},"recipe_readded":[]}